Publications by authors named "Calum MacRae"

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Pragmatic Approaches to the Evaluation and Monitoring of Artificial Intelligence in Health Care: A Science Advisory From the American Heart Association.
Sneha S Jain, Shinichi Goto, Jennifer L Hall, Sadiya S Khan, Calum A MacRae

Circulation· December 2025

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Genetic testing in cardiology: insights into 'overlap' from atrial fibrillation.
Calum A MacRae

Eur Heart J· December 2025

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Convolutional Neural Network Models Leverage Morphological Rather Than Temporal Features to Detect Myocardial Diseases From 12-Lead Electrocardiograms.
Masamitsu Nakayama, Ryuichiro Yagi, Yoshinori Katsumata, Masayuki Oki, Rahul C Deo, Calum A MacRae

Circ Arrhythm Electrophysiol· December 2025

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Phenotypic screening for new heart failure therapeutics: scalable animal modeling in zebrafish.
Calum A MacRae

Expert Opin Drug Discov· October 2025

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Characterisation of an allosteric site in PLCγ enzymes and implications for development of their specific inhibitors.
Tom D Bunney, Hunter G Nyvall, Calum Macrae, Damjan Lalović, Ashley Gregory

Biochem J· October 2025

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The functional landscape of coding variation in the familial hypercholesterolemia gene .
Daniel R Tabet, Atina G Coté, Megan C Lancaster, Jochen Weile, Ashyad Rayhan, Calum A MacRae

Science· October 2025

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Precision cardiovascular medicine: shifting the innovation paradigm.
Masanori Aikawa, Abhijeet R Sonawane, Sarvesh Chelvanambi, Takaharu Asano, Arda Halu, Calum A MacRae

Front Sci· October 2025

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Creating an atlas of variant effects to resolve variants of uncertain significance and guide cardiovascular medicine.
Andrew M Glazer, Daniel R Tabet, Victoria N Parikh, Brett M Kroncke, Atina G Cote, Calum A Macrae

Nat Rev Cardiol· September 2025

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PIEZO1 Activation-Mediated Generation of Transgene-Free Long-Term Hematopoietic Stem Cells.
Giorgia Scapin, Jennifer L Cillis, Marie C Goulard, Taylor C Patch, Cintia E Gomez Limia, Calum A MacRae

Am J Hematol· June 2025

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Phosphoinositide-specific phospholipase C enzymes: Recent advances in a long journey.
Calum Macrae, Damjan Lalović, Tom D Bunney, Matilda Katan

Biochim Biophys Acta Mol Cell Biol Lipids· June 2025

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Scaled multidimensional assays of variant effect identify sequence-function relationships in hypertrophic cardiomyopathy.
Yuta Yamamoto, Kaiser Chua, Alexis Ferrasse, Anna Kirilova, Hannah N De Jong, Calum MacRae

bioRxiv· May 2025

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Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy.
Qinghong Li, Max Homilius, Erin Achilles, Laura K Massey, Victoria Convey, Calum A MacRae

ESC Heart Fail· April 2025

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Characterization and natural history of patients with LMNA-related dilated cardiomyopathy in the phase 3 REALM-DCM trial.
Pablo Garcia-Pavia, Neal K Lakdawala, Gianfranco Sinagra, Tomas Ripoll-Vera, Kia Afshar, Calum A MacRae

ESC Heart Fail· December 2024

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Safety and tolerability of the M2 muscarinic acetylcholine receptor modulator BAY 2413555 in heart failure with reduced ejection fraction in the REMOTE-HF study.
Marat Fudim, Muhammad Shahzeb Khan, Dominik Linz, JoAnn Lindenfeld, Calum MacRae

Sci Rep· December 2024

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Suppression of cyclooxygenase-2 predisposes to heart failure with preserved ejection fraction.
Emanuela Ricciotti, Philip G Haines, Manu Beerens, Uri Kartoun, Cecilia Castro, Calum A MacRae

bioRxiv· November 2024

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Standardizing CRISPR-Cas13 knockdown technique to investigate the role of cdh2 gene in pituitary development through growth hormone expression and transcription factors.
Bianca Helena Ventura Fernandes, Mara S Junqueira, Calum MacRae, Luciani R Silveira de Carvalho

Front Endocrinol (Lausanne)· October 2024

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Software-driven chronic disease management: Algorithm design and implementation in a community-based blood pressure control pilot.
Rahul C Deo, Rebecca Smith, Calum A MacRae, Esha Price, Horace Sheffield

SAGE Open Med· October 2024

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Understanding activity and physiology at scale: The Apple Heart & Movement Study.
James Truslow, Angela Spillane, Huiming Lin, Katherine Cyr, Adeeti Ullal, Calum A MacRae

NPJ Digit Med· September 2024

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REALM-DCM: A Phase 3, Multinational, Randomized, Placebo-Controlled Trial of ARRY-371797 in Patients With Symptomatic -Related Dilated Cardiomyopathy.
Pablo Garcia-Pavia, Jose Fernando Rodriguez Palomares, Gianfranco Sinagra, Roberto Barriales-Villa, Neal K Lakdawala, Calum A MacRae

Circ Heart Fail· July 2024

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Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease.
Suvi Linna-Kuosmanen, Eloi Schmauch, Kyriakitsa Galani, Johannes Ojanen, Carles A Boix, Calum A MacRae

Cell Rep Med· May 2024

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Personalized Intervention Based on Early Detection of Atherosclerosis: JACC State-of-the-Art Review.
Rikke V Nielsen, Valentin Fuster, Henning Bundgaard, Jose J Fuster, Amer M Johri, Calum MacRae

J Am Coll Cardiol· May 2024

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Artificial intelligence-enabled prediction of chemotherapy-induced cardiotoxicity from baseline electrocardiograms.
Ryuichiro Yagi, Shinichi Goto, Yukihiro Himeno, Yoshinori Katsumata, Masahiro Hashimoto, Calum A MacRae

Nat Commun· March 2024

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Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases.
Max Homilius, Wandi Zhu, Samuel S Eddy, Patrick C Thompson, Huahua Zheng, Calum A MacRae

Nat Genet· January 2024

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The Role of and Microtubules in Maintaining Normal Ventricular Conduction.
David Y Chiang, Arie O Verkerk, Rachelle Victorio, Boris I Shneyer, Babet van der Vaart, Calum A MacRae

Circ Res· January 2024

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Enhancing the sensitivity of atom-interferometric inertial sensors using robust control.
Jack C Saywell, Max S Carey, Philip S Light, Stuart S Szigeti, Alistair R Milne, Calum D Macrae

Nat Commun· November 2023

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