Publications by authors named "Camil Sayegh"

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Human in vitro neuromuscular junction model to functionally dissect the pathogenic mechanism of anti-AChR autoantibody-positive myasthenia gravis.
Baehyun Shin, Monica Wang, John Yim, Elisa Kwon, Margaret H Magdesian, Camil E Sayegh

BMC Pharmacol Toxicol· December 2025

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Phase II trials of zilucoplan in paroxysmal nocturnal hemoglobinuria.
Austin G Kulasekararaj, Anna-Elina Lehtinen, Cecily Forsyth, Shreyans Gandhi, Morag Griffin, Camil E Sayegh

Haematologica· March 2024

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Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation.
Guo-Qing Tang, Yalan Tang, Ketki Dhamnaskar, Michelle D Hoarty, Rohit Vyasamneni, Camil Sayegh

Front Immunol· September 2023

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Corrigendum: Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation.
Guo-Qing Tang, Yalan Tang, Ketki Dhamnaskar, Michelle D Hoarty, Rohit Vyasamneni, Camil Sayegh

Front Immunol· September 2023

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Zilucoplan in immune-mediated necrotising myopathy: a phase 2, randomised, double-blind, placebo-controlled, multicentre trial.
Andrew L Mammen, Anthony A Amato, Mazen M Dimachkie, Hector Chinoy, Yessar Hussain, Camil Sayegh

Lancet Rheumatol· February 2023

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Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model.
Sarah Julien, Douangsone Vadysirisack, Camil Sayegh, Sharan Ragunathan, Yalan Tang

Biomedicines· August 2022

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Human Neutrophils Respond to Complement Activation and Inhibition in Microfluidic Devices.
Sinan Muldur, Douangsone D Vadysirisack, Sharan Ragunathan, Yalan Tang, Alonso Ricardo, Camil Elie Sayegh

Front Immunol· February 2022

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The PAR2 inhibitor I-287 selectively targets Gα and Gα signaling and has anti-inflammatory effects.
Charlotte Avet, Claudio Sturino, Sébastien Grastilleur, Christian Le Gouill, Meriem Semache, Camil E Sayegh

Commun Biol· November 2020

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Molecular and genetic inflammation networks in major human diseases.
Yongzhong Zhao, Christian V Forst, Camil E Sayegh, I-Ming Wang, Xia Yang

Mol Biosyst· July 2016

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Assessing protein-RNA interactions using microfluidic capillary mobility shift assays.
Jimmy Fourtounis, Jean-Pierre Falgueyret, Camil Elie Sayegh

Anal Biochem· April 2011

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Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis.
Anne-Marie Pulichino, I-Ming Wang, Alexandre Caron, James Mortimer, Anick Auger, Camil E Sayegh

Am J Respir Cell Mol Biol· September 2008

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Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells.
Camil E Sayegh, Suchit Jhunjhunwala, Roy Riblet, Cornelis Murre

Genes Dev· February 2005

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E-proteins directly regulate expression of activation-induced deaminase in mature B cells.
Camil Elie Sayegh, Melanie W Quong, Yasutoshi Agata, Cornelis Murre

Nat Immunol· June 2003

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