Publications by authors named "Cammie F Lesser"

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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ.
Kevin D Eislmayr, Charlotte A Nichols, Fitty L Liu, Sudyut Yuvaraj, Janet Peace Babirye, Cammie F Lesser

Cell Host Microbe· September 2025

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The bacterial type three secretion system induces mechanoporation of vacuolar membranes.
Léa Swistak, Marvin Albert, Camila Valenzuela, Elif Begum Gokerkucuk, François Bontems, Cammie F Lesser

PLoS Biol· May 2025

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The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria.
Katherine Schubert, Jessica Zhang, Michele E Muscolo, Micah Braly, Joshua W McCausland, Cammie F Lesser

PLoS Pathog· May 2025

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OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.
Elizabeth A Turcotte, Kyungsub Kim, Kevin D Eislmayr, Lisa Goers, Patrick S Mitchell, Cammie F Lesser

bioRxiv· February 2025

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Macrophages orchestrate elimination of from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ.
Kevin D Eislmayr, Charlotte Langner, Fitty L Liu, Sudyut Yuvaraj, Janet Peace Babirye, Cammie F Lesser

bioRxiv· January 2025

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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
Yutao Wang, Yanbo Zhang, Kyungsub Kim, Jichang Han, Daniel Okin, Cammie F Lesser

Immunity· December 2024

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The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria.
Katherine Schubert, Micah Braly, Jessica Zhang, Michele E Muscolo, Hanh N Lam, Cammie F Lesser

bioRxiv· November 2024

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Living Engineered Bacterial Therapeutics: Emerging Affordable Precision Interventions.
Rajkamal Srivastava, Cammie F Lesser

Microb Biotechnol· November 2024

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Gut bacterial type III secretion systems aggravate colitis in mice and serve as biomarkers of Crohn's disease.
Jun Xu, Peijie Li, Zhenye Li, Sheng Liu, Huating Guo, Cammie F Lesser

EBioMedicine· September 2024

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deposition of nanobodies by an engineered commensal microbe promotes survival in a mouse model of enterohemorrhagic .
Rajkamal Srivastava, Coral González-Prieto, Jason P Lynch, Michele E Muscolo, Catherine Y Lin, Cammie F Lesser

PNAS Nexus· September 2024

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deposition of nanobodies by an engineered commensal microbe promotes survival in a mouse model of enterohemorrhagic .
Rajkamal Srivastava, Coral González-Prieto, Jason P Lynch, Michele Muscolo, Catherine Y Lin, Cammie F Lesser

bioRxiv· July 2024

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PROTEcT, engineered Escherichia coli for the targeted delivery of therapeutics.
Coral González-Prieto, Jason P Lynch, Cammie F Lesser

Trends Mol Med· November 2023

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Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.
Jason P Lynch, Coral González-Prieto, Analise Z Reeves, Sena Bae, Urmila Powale, Cammie F Lesser

Cell Host Microbe· April 2023

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IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation.
Lisa Goers, Kyungsub Kim, Teagan C Stedman, Patrick J Canning, Xiangyu Mou, Cammie F Lesser

Proc Natl Acad Sci U S A· April 2023

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LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro.
Mary S Dickinson, Miriam Kutsch, Linda Sistemich, Dulcemaria Hernandez, Anthony S Piro, Cammie F Lesser

Proc Natl Acad Sci U S A· April 2023

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Case Report and Clinical Reasoning: Fulminant Liver Failure and Invasive Aspergillosis Following Ocrelizumab Treatment in a 21 Year-Old Woman.
Caleb R S McEntire, Cammie F Lesser, Nagagopal Venna

Neurohospitalist· January 2023

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A hierarchy of cell death pathways confers layered resistance to shigellosis in mice.
Justin L Roncaioli, Janet Peace Babirye, Roberto A Chavez, Fitty L Liu, Elizabeth A Turcotte, Cammie F Lesser

Elife· January 2023

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Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics.
Jason P Lynch, Lisa Goers, Cammie F Lesser

Trends Pharmacol Sci· September 2022

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A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.
Noémie Alphonse, Joseph J Wanford, Andrew A Voak, Jack Gay, Shayla Venkhaya, Cammie F Lesser

Cell· June 2022

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The Spp. Type III Effector Protein OspB Is a Cysteine Protease.
Thomas E Wood, Kathleen A Westervelt, Jessica M Yoon, Heather D Eshleman, Roie Levy, Cammie F Lesser

mBio· June 2022

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Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Jennifer Cable, Joshua N Leonard, Timothy K Lu, Zhen Xie, Matthew Wook Chang, Cammie F Lesser

Ann N Y Acad Sci· December 2021

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The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.
Miriam Kutsch, Coral González-Prieto, Cammie F Lesser, Jörn Coers

Pathog Dis· April 2021

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A host metabolite promotes survival.
Jason P Lynch, Cammie F Lesser

Science· January 2021

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NAIP-NLRC4-deficient mice are susceptible to shigellosis.
Patrick S Mitchell, Justin L Roncaioli, Elizabeth A Turcotte, Lisa Goers, Roberto A Chavez, Cammie F Lesser

Elife· October 2020

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Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.
Miriam Kutsch, Linda Sistemich, Cammie F Lesser, Marcia B Goldberg, Christian Herrmann

EMBO J· July 2020

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