Publications by authors named "Candace Graff"

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An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
Michael J McPherson, Adrian D Hobson, Axel Hernandez, Christopher C Marvin, Wendy Waegell, Candace Graff

Sci Transl Med· March 2024

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Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712.
Eric Breinlinger, Stacy Van Epps, Michael Friedman, Maria Argiriadi, Ellen Chien, Candace Graff

J Med Chem· October 2023

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Correction to "Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate".
Adrian D Hobson, Michael J McPherson, Martin E Hayes, Christian Goess, Xiang Li, Candace Graff

J Med Chem· April 2023

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Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate.
Adrian D Hobson, Michael J McPherson, Martin E Hayes, Christian Goess, Xiang Li, Candace Graff

J Med Chem· December 2022

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Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits.
Charles Mattis, Natalie Bratcher, Monika Burns, Christopher Carosino, Christina de Zafra, Candace Graff

Int J Toxicol· August 2022

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In vitro and in vivo characterization of the JAK1 selectivity of upadacitinib (ABT-494).
Julie M Parmentier, Jeff Voss, Candace Graff, Annette Schwartz, Maria Argiriadi

BMC Rheumatol· August 2018

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Systemic administration of an Fcgamma-Fc(epsilon)-fusion protein in house dust mite sensitive nonhuman primates.
Michael R Van Scott, Elisabeth Mertsching, Ella Negrou, Jeremy Miles, Howard W Stallings, Candace Graff

Clin Immunol· September 2008

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Nasal drug administration: potential for targeted central nervous system delivery.
Candace L Graff, Gary M Pollack

J Pharm Sci· June 2005

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Pharmacokinetics of substrate uptake and distribution in murine brain after nasal instillation.
Candace L Graff, Rong Zhao, Gary M Pollack

Pharm Res· February 2005

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Functional evidence for P-glycoprotein at the nose-brain barrier.
Candace L Graff, Gary M Pollack

Pharm Res· January 2005

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Use of loperamide as a phenotypic probe of mdr1a status in CF-1 mice.
J Cory Kalvass, Candace L Graff, Gary M Pollack

Pharm Res· October 2004

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Drug transport at the blood-brain barrier and the choroid plexus.
Candace L Graff, Gary M Pollack

Curr Drug Metab· February 2004

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Variable modulation of opioid brain uptake by P-glycoprotein in mice.
Claude Dagenais, Candace L Graff, Gary M Pollack

Biochem Pharmacol· January 2004

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P-Glycoprotein attenuates brain uptake of substrates after nasal instillation.
Candace L Graff, Gary M Pollack

Pharm Res· August 2003

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