Publications by authors named "Carl Machutta"

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Acoustic Mist Ionization-Mass Spectrometry: A Comparison to Conventional High-Throughput Screening and Compound Profiling Platforms.
Arseniy M Belov, Joseph Kozole, Mark F Bean, Carl A Machutta, Guofeng Zhang

Anal Chem· October 2020

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Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan

Nat Commun· July 2018

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Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan

Nat Commun· July 2017

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Thiolactomycin-based β-ketoacyl-AcpM synthase A (KasA) inhibitors: fragment-based inhibitor discovery using transient one-dimensional nuclear overhauser effect NMR spectroscopy.
Kanishk Kapilashrami, Gopal R Bommineni, Carl A Machutta, Pilho Kim, Cheng-Tsung Lai

J Biol Chem· March 2013

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Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.
Elsie Diaz, Carl A Machutta, Stephanie Chen, Yong Jiang, Christopher Nixon

J Biomol Screen· December 2012

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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.
Sharad K Verma, Xinrong Tian, Louis V LaFrance, Céline Duquenne, Dominic P Suarez, Carl A Machutta

ACS Med Chem Lett· December 2012

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Substrate recognition by β-ketoacyl-ACP synthases.
Janine G Borgaro, Andrew Chang, Carl A Machutta, Xujie Zhang, Peter J Tonge

Biochemistry· December 2011

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Slow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin.
Carl A Machutta, Gopal R Bommineni, Sylvia R Luckner, Kanishk Kapilashrami, Bela Ruzsicska

J Biol Chem· February 2010

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Crystal structures of Mycobacterium tuberculosis KasA show mode of action within cell wall biosynthesis and its inhibition by thiolactomycin.
Sylvia R Luckner, Carl A Machutta, Peter J Tonge, Caroline Kisker

Structure· July 2009

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Substrate recognition by the human fatty-acid synthase.
Loretha Carlisle-Moore, Chris R Gordon, Carl A Machutta, W Todd Miller, Peter J Tonge

J Biol Chem· December 2005

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Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis.
James J Truglio, Karsten Theis, Yuguo Feng, Ramona Gajda, Carl Machutta

J Biol Chem· October 2003

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