Publications by authors named "Carl Mendel"

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Bedaquiline-Pretomanid-Linezolid Regimens for Drug-Resistant Tuberculosis.
Francesca Conradie, Tatevik R Bagdasaryan, Sergey Borisov, Pauline Howell, Lali Mikiashvili, Carl M Mendel

N Engl J Med· September 2022

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An Exposure-Response Perspective on the Clinical Dose of Pretomanid.
Jerry R Nedelman, David H Salinger, Vishak Subramoney, Rob Woolson, Karen Wade, Carl M Mendel

Antimicrob Agents Chemother· December 2020

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Reply to Kim et al., "Optimal Dose or Optimal Exposure? Consideration for Linezolid in Tuberculosis Treatment".
Andreas H Diacon, Veronique R De Jager, Rodney Dawson, Kim Narunsky, Naadira Vanker, Carl M Mendel

Antimicrob Agents Chemother· June 2020

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Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis.
Andreas H Diacon, Veronique R De Jager, Rodney Dawson, Kim Narunsky, Naadira Vanker, Carl M Mendel

Antimicrob Agents Chemother· March 2020

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Treatment of Highly Drug-Resistant Pulmonary Tuberculosis.
Francesca Conradie, Andreas H Diacon, Nosipho Ngubane, Pauline Howell, Daniel Everitt, Carl M Mendel

N Engl J Med· March 2020

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Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant pulmonary tuberculosis: a multicentre, open-label, partially randomised, phase 2b trial.
Conor D Tweed, Rodney Dawson, Divan A Burger, Almari Conradie, Angela M Crook, Carl M Mendel

Lancet Respir Med· December 2019

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Daily Dosing for Bedaquiline in Patients with Tuberculosis.
David H Salinger, Jerry R Nedelman, Carl Mendel, Melvin Spigelman, David J Hermann

Antimicrob Agents Chemother· November 2019

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Long-Term Effects on QT Prolongation of Pretomanid Alone and in Combinations in Patients with Tuberculosis.
Hanbin Li, David H Salinger, Daniel Everitt, Mengchun Li, Angelo Del Parigi, Carl Mendel

Antimicrob Agents Chemother· October 2019

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Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.
Conor D Tweed, Angela M Crook, Rodney Dawson, Andreas H Diacon, Timothy D McHugh, Carl M Mendel

BMC Pulm Med· August 2019

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Toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Conor D Tweed, Angela M Crook, Evans I Amukoye, Rodney Dawson, Andreas H Diacon, Carl M Mendel

BMC Infect Dis· July 2018

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Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Conor Duncan Tweed, Genevieve Helen Wills, Angela M Crook, Rodney Dawson, Andreas H Diacon, Carl Mendel

BMC Med· March 2018

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A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens.
Patrick P J Phillips, Carl M Mendel, Andrew J Nunn, Timothy D McHugh, Angela M Crook

BMC Med· November 2017

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Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis.
Michael E Murphy, Patrick P J Phillips, Carl M Mendel, Emily Bongard, Anna L C Bateson

BMC Med· October 2017

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Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
Patrick P J Phillips, Carl M Mendel, Divan A Burger, Angela M Crook, Andrew J Nunn

BMC Med· February 2016

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Erratum to: Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
Patrick P J Phillips, Carl M Mendel, Divan A Burger, Angela M Crook, Andrew J Nunn

BMC Med· February 2016

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Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis.
Rokeya Tasneen, Fabrice Betoudji, Sandeep Tyagi, Si-Yang Li, Kathy Williams, Carl M Mendel

Antimicrob Agents Chemother· January 2016

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Towards early inclusion of children in tuberculosis drugs trials: a consensus statement.
Sharon Nachman, Amina Ahmed, Farhana Amanullah, Mercedes C Becerra, Radu Botgros, Carl Mendel

Lancet Infect Dis· June 2015

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Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pulmonary tuberculosis.
Rodney Dawson, Andreas H Diacon, Daniel Everitt, Christo van Niekerk, Peter R Donald, Carl M Mendel

Lancet· May 2015

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Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline.
Andreas H Diacon, Rodney Dawson, Florian von Groote-Bidlingmaier, Gregory Symons, Amour Venter, Carl M Mendel

Am J Respir Crit Care Med· April 2015

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Shorter moxifloxacin-based regimens for drug-sensitive tuberculosis.
Stephen H Gillespie, Carl M Mendel,

N Engl J Med· February 2015

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Rapid sequencing of the Mycobacterium tuberculosis pncA gene for detection of pyrazinamide susceptibility.
Elizabeth M Streicher, Kashmeel Maharaj, Talita York, Carel Van Heerden, Marinus Barnard, Carl M Mendel

J Clin Microbiol· November 2014

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Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis.
Stephen H Gillespie, Angela M Crook, Timothy D McHugh, Carl M Mendel, Sarah K Meredith

N Engl J Med· October 2014

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Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis.
Andreas H Diacon, Rodney Dawson, Florian Von Groote-Bidlingmaier, Gregory Symons, Amour Venter, Carl M Mendel

Antimicrob Agents Chemother· May 2013

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Early bactericidal activity of new drug regimens for tuberculosis - Authors' reply.
Andreas H Diacon, Peter R Donald, Carl M Mendel

Lancet· January 2013

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14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trial.
Andreas H Diacon, Rodney Dawson, Florian von Groote-Bidlingmaier, Gregory Symons, Amour Venter, Carl M Mendel

Lancet· September 2012

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