Publications by authors named "Carlos de Castro"

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Patient-Reported Meaningful Change in Symptoms and Impacts of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Three Phase III Clinical Trials of Iptacopan.
Carlos DeCastro, Phillip Sheinberg, Bing Han, Susan Vallow, Georgina Bermann

Patient· November 2025

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Efficacy and Safety Maintained up to 3 Years in Adults with Paroxysmal Nocturnal Hemoglobinuria Receiving Pegcetacoplan.
Carlos de Castro, Richard J Kelly, Morag Griffin, Christopher J Patriquin, Brian Mulherin

Adv Ther· September 2025

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Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors.
Antonio M Risitano, Austin G Kulasekararaj, Phillip Scheinberg, Alexander Röth, Bing Han, Carlos M de Castro

Lancet Haematol· June 2025

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Patient-reported improvements in paroxysmal nocturnal hemoglobinuria treated with iptacopan from 2 phase 3 studies.
Antonio M Risitano, Carlos de Castro, Bing Han, Austin Kulasekararaj, Jaroslaw P Maciejewski

Blood Adv· April 2025

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Iptacopan for the treatment of paroxysmal nocturnal hemoglobinuria.
Carlos M de Castro, Bhumika J Patel

Expert Opin Pharmacother· December 2024

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Chrysin attenuates epithelial prostatic hyperplasia in the ventral prostate of spontaneously hypertensive rats.
Nathany R L Dos Santos, Gessica C de Sousa, Phâmella N Lima, Bárbara C M Medeiros, Luana A Manso, Carlos H de Castro

Cell Biol Int· October 2024

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Modified Delphi panel consensus recommendations for management of severe aplastic anemia.
Daria V Babushok, Amy E DeZern, Carlos M de Castro, Zora R Rogers, David Beenhouwer

Blood Adv· August 2024

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Hemolysis events in the phase 3 PEGASUS study of pegcetacoplan in patients with paroxysmal nocturnal hemoglobinuria.
Régis Peffault de Latour, Morag Griffin, Richard J Kelly, Jeff Szer, Carlos de Castro

Blood Adv· June 2024

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Early Methylglyoxal Exposure Leads to Worsened Cardiovascular Function in Young Rats.
Marcos Divino Ferreira-Junior, Keilah Valéria N Cavalcante, Jaqueline M Costa, Amanda S M Bessa, Andreia Amaro, Carlos Henrique de Castro

Nutrients· June 2024

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Sodium overload during postnatal phases impairs diastolic function and exacerbates reperfusion arrhythmias in adult rats.
Marina Conceição Dos Santos Moreira, Allancer Divino de Carvalho Nunes, Paulo Ricardo Lopes, Cintia do Carmo Silva, Stefanne Madalena Marques, Carlos Henrique de Castro

J Dev Orig Health Dis· May 2024

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Advancements in enzyme immobilization on magnetic nanomaterials: toward sustainable industrial applications.
Antônio Luthierre Gama Cavalcante, Dayana Nascimento Dari, Francisco Izaias da Silva Aires, Erico Carlos de Castro, Kaiany Moreira Dos Santos

RSC Adv· May 2024

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Management of acute breakthrough hemolysis with intensive pegcetacoplan dosing in patients with PNH.
Morag Griffin, Richard J Kelly, Jens Panse, Carlos de Castro, Jeff Szer

Blood Adv· April 2024

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Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria.
Régis Peffault de Latour, Alexander Röth, Austin G Kulasekararaj, Bing Han, Phillip Scheinberg, Carlos M de Castro

N Engl J Med· March 2024

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Protein coronas coating polymer-stabilized silver nanocolloids attenuate cytotoxicity with minor effects on antimicrobial performance.
Carin C S Batista, Karine Panico, Jiří Trousil, Olga Janoušková, Carlos Eduardo de Castro

Colloids Surf B Biointerfaces· October 2022

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Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial.
Régis Peffault de Latour, Jeff Szer, Ilene C Weitz, Alexander Röth, Britta Höchsmann, Carlos M de Castro

Lancet Haematol· September 2022

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Confirmation of Ectopic Pancreatic Tissue: A Novel Use for 18 F-Fluciclovine PET.
Eric J Keller, Carlos Manuel de Castro, Pejman Ghanouni, Jagruti Shah

Clin Nucl Med· August 2022

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C and N stocks in silvopastoral systems with high and low tree diversity: Evidence from a twenty-two year old field study.
Jorge Cá, José Ferreira Lustosa Filho, Neilson Rocha da Silva, Carlos Renato Tavares de Castro, Teogenes Senna de Oliveira

Sci Total Environ· August 2022

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Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe.
Francesca Giuffrida, Mathilde Fleith, Amélie Goyer, Tinu Mary Samuel, Isabelle Elmelegy-Masserey, Carlos Antonio De Castro

Eur J Nutr· June 2022

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Ready-to-use room temperature one-pot synthesis of surface-decorated gold nanoparticles with targeting attributes.
Caroline A S Ribeiro, Lindomar J C Albuquerque, Carlos E de Castro, Rodrigo M Pereira, Brunno L Albuquerque

J Colloid Interface Sci· May 2022

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Maternal postnatal early overfeeding induces sex-related cardiac dysfunction and alters sexually hormones levels in young offspring.
Lucas Araújo Ferreira, Marcos Divino Ferreira-Junior, Keytiane de Jesus Viana Amaral, Keilah Valéria Naves Cavalcante, Carolina Nobre Ribeiro Pontes, Carlos Henrique de Castro

J Nutr Biochem· May 2022

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Oral Treatment with Angiotensin-(1-7) Attenuates the Kidney Injury Induced by Gentamicin in Wistar Rats.
Lílian Fernanda Pacheco, Carlos Henrique de Castro, João Batista Rodrigues Dutra, Ruy de Souza Lino Junior, Patrícia Maria Ferreira

Protein Pept Lett· February 2022

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NCCN Guidelines® Insights: Myelodysplastic Syndromes, Version 3.2022.
Peter L Greenberg, Richard M Stone, Aref Al-Kali, John M Bennett, Uma Borate, Carlos M de Castro

J Natl Compr Canc Netw· February 2022

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Phase II Study of Single-Agent and Combination Everolimus and Panobinostat in Relapsed or Refractory Diffuse Large B-Cell Lymphoma.
Prioty Islam, David Rizzieri, Chenyu Lin, Carlos de Castro, Louis Diehl

Cancer Invest· November 2021

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Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.
Cindy M Pabon, Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L Neff

Blood Cancer J· May 2021

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Medullary Noradrenergic Neurons Mediate Hemodynamic Responses to Osmotic and Volume Challenges.
Stefanne Madalena Marques, Lara Marques Naves, Talita de Melo E Silva, Keilah Valéria Naves Cavalcante, Juliana Milan Alves, Carlos Henrique de Castro

Front Physiol· April 2021

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