Publications by authors named "Carson Reed"

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A human-compatible gradient coil for visualizing ultrasound propagation.
Paul-Emile Passe-Carlus, Davi Cavinatto, Nathan Thyberg, Carson Reed, Taylor D Webb

Magn Reson Imaging· October 2025

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Further Optimization of the mGlu PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685.
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, Trevor A Trombley, Paul K Spearing

ACS Chem Neurosci· February 2025

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Discovery of VU6024578/BI02982816: An mGlu Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models.
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, Trevor A Trombley, Anthony F Nastase

J Med Chem· December 2024

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Development and profiling of mGlu NAMs with a range of saturable inhibition of agonist responses in vitro.
Carson W Reed, Alice L Rodriguez, Jacob J Kalbfleisch, Mabel Seto, Matthew T Jenkins

Bioorg Med Chem Lett· October 2022

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Differential activity of mGlu allosteric modulators provides evidence for mGlu heterodimers at hippocampal Schaffer collateral-CA1 synapses.
Xin Lin, Nicole M Fisher, Shalini Dogra, Rebecca K Senter, Carson W Reed

J Biol Chem· October 2022

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Synthesis and SAR of a series of mGlu NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core.
Jacob J Kalbfleisch, Carson W Reed, Charlotte Park, Paul K Spearing, Marc C Quitalig

Bioorg Med Chem Lett· November 2020

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Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu Positive Allosteric Modulator Tool Compound.
Carson W Reed, Jacob J Kalbfleisch, Madison J Wong, Jordan P Washecheck, Ashton Hunter

ACS Med Chem Lett· September 2020

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Formal Total Synthesis of Pericoannosin A.
Mark G Fulton, Jeanette L Bertron, Carson W Reed, Craig W Lindsley

J Org Chem· September 2019

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Surveying heterocycles as amide bioisosteres within a series of mGlu NAMs: Discovery of VU6019278.
Carson W Reed, Jordan P Washecheck, Marc C Quitlag, Matthew T Jenkins, Alice L Rodriguez

Bioorg Med Chem Lett· May 2019

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Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1 H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962).
Carson W Reed, Samantha E Yohn, Jordan P Washecheck, Hanna F Roenfanz, Marc C Quitalig

J Med Chem· February 2019

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Use of chemical probes to explore the toxicological potential of the K/Cl cotransporter (KCC) as a novel insecticide target to control the primary vector of dengue and Zika virus, Aedes aegypti.
Francis J Prael, Rui Chen, Zhilin Li, Carson W Reed, Craig W Lindsley

Pestic Biochem Physiol· October 2018

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VU6010608, a Novel mGlu NAM from a Series of -(2-(1-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides.
Carson W Reed, Kevin M McGowan, Paul K Spearing, Branden J Stansley, Hanna F Roenfanz

ACS Med Chem Lett· December 2017

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Kemp Elimination in Cationic Micelles: Designed Enzyme-Like Rates Achieved through the Addition of Long-Chain Bases.
Enis Sanchez, Steven Lu, Carson Reed, Joshua Schmidt, Marcello Forconi

J Phys Org Chem· April 2016

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