Publications by authors named "Mabel Seto"

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Blood gene expression network expression strongly relates to brain amyloid burden.
Vaibhav A Janve, Mabel Seto, Reisa A Sperling, Paul S Aisen, Robert A Rissman

Alzheimers Dement· December 2025

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Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease.
Mabel Seto, Hannah M Klinger, Michelle Clifton, Vaibhav A Janve, Jane A Brown

bioRxiv· November 2025

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Sex-specific associations of gene expression with Alzheimer's disease neuropathology and ante-mortem cognitive performance.
Mabel Seto, Michelle Clifton, Melisa Lara Gomez, Gillian Coughlan, Katherine A Gifford

Nat Commun· October 2025

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Midlife Steroid-Binding Globulin Levels and In Vivo Neuroimaging Measures of Tau in Older Men and Women.
Rachel F Buckley, Matthew Scott, Emer R McGrath, Gillian Coughlan, Mabel Seto

Ann Neurol· September 2025

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BrainAge moderates associations between Alzheimer's disease biomarkers and cognitive decline: a meta-analysis across A4/LEARN, HABS and ADNI cohorts.
Jorge Garcia Condado, Hannah M Klinger, Colin Birkenbihl, Madison Cuppels, Annie Liu, Mabel Seto

medRxiv· July 2025

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Relationship between BrainAge Polygenetic Risk Score and plasma biomarkers in the A4/LEARN studies.
Jorge Garcia Condado, Mabel Seto, Madison Cuppels, Colin Birkenbihl, Hannah M Klinger

medRxiv· July 2025

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Resistance and resilience to Alzheimer's disease in Down syndrome.
Rory Boyle, Elouise A Koops, Beau Ances, Elizabeth J Andrews, Eider M Arenaza-Urquijo, Mabel Seto

Alzheimers Dement· April 2025

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Sex Differences in Longitudinal Tau-PET in Preclinical Alzheimer Disease: A Meta-Analysis.
Gillian T Coughlan, Hannah M Klinger, Rory Boyle, Tobey J Betthauser, Alexa Pichet Binette, Mabel Seto

JAMA Neurol· March 2025

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Associations between hormone therapy use and tau accumulation in brain regions vulnerable to Alzheimer's disease.
Gillian T Coughlan, Zoe Rubinstein, Hannah Klinger, Kelly A Lopez, Stephaine Hsieh, Mabel Seto

Sci Adv· March 2025

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Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.
Logan Dumitrescu, Mabel Seto, Michelle Clifton, Melisa Lara Gomez, Gillian Coughlan

Res Sq· March 2025

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Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.
Mabel Seto, Michelle Clifton, Melisa Lara Gomez, Gillian Coughlan, Katherine A Gifford

bioRxiv· January 2025

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Latent change-on-change between amyloid accumulation and cognitive decline.
Hannah M Klinger, Brian C Healy, Bernard J Hanseeuw, Rich N Jones, Rory Boyle, Mabel Seto

Alzheimers Dement· December 2024

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Pathologic and clinical correlates of region-specific brain GFAP in Alzheimer's disease.
Jared M Phillips, Rebecca L Winfree, Mabel Seto, Julie A Schneider, David A Bennett

Acta Neuropathol· November 2024

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How Is the X Chromosome Involved in Alzheimer Disease?
Rachel F Buckley, Mabel Seto

JAMA Neurol· October 2024

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Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer's disease predicts cognitive decline.
Rebecca L Winfree, Kevin Erreger, Jared Phillips, Mabel Seto, Yanling Wang

Neurobiol Aging· August 2024

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Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults.
Mabel Seto, Timothy J Hohman, Elizabeth C Mormino, Kathryn V Papp, Rebecca E Amariglio

JAMA Neurol· August 2024

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Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau, and neurodegeneration.
Rory Boyle, Diana L Townsend, Hannah M Klinger, Catherine E Scanlon, Ziwen Yuan, Mabel Seto

Alzheimers Res Ther· July 2024

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Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.
Rebecca L Winfree, Emma Nolan, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Mabel Seto

Mol Neurodegener· May 2024

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Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.
Mabel Seto, Logan Dumitrescu, Emily R Mahoney, Annah M Sclafani, Philip L De Jager

Neurobiol Aging· June 2023

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TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.
Rebecca L Winfree, Mabel Seto, Logan Dumitrescu, Vilas Menon, Philip De Jager

Acta Neuropathol· June 2023

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Whole blood transcript and protein abundance of the vascular endothelial growth factor family relate to cognitive performance.
Julia B Libby, Mabel Seto, Omair A Khan, Dandan Liu, Vlad Petyuk

Neurobiol Aging· April 2023

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RNASE6 is a novel modifier of APOE-ε4 effects on cognition.
Mabel Seto, Rebecca L Weiner, Logan Dumitrescu, Emily R Mahoney, Shania L Hansen

Neurobiol Aging· October 2022

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Development and profiling of mGlu NAMs with a range of saturable inhibition of agonist responses in vitro.
Carson W Reed, Alice L Rodriguez, Jacob J Kalbfleisch, Mabel Seto, Matthew T Jenkins

Bioorg Med Chem Lett· October 2022

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Exploring common genetic contributors to neuroprotection from amyloid pathology.
Mabel Seto, Emily R Mahoney, Logan Dumitrescu, Vijay K Ramanan, Corinne D Engelman

Brain Commun· March 2022

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Protective genes and pathways in Alzheimer's disease: moving towards precision interventions.
Mabel Seto, Rebecca L Weiner, Logan Dumitrescu, Timothy J Hohman

Mol Neurodegener· April 2021

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