Publications by authors named "Carsten Hopf"

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Local accumulation of very long-chain PUFA in plexiform layers associates with retinal dysfunction in a mouse model of peroxisomal ACBD5-deficiency.
Julia Merz, Elisabeth Müller, Warda Darwisch, Richard Fairless, Yixin Wang, Carsten Hopf

Cell Mol Life Sci· December 2025

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A sulfatide-centered ultra-high resolution magnetic resonance MALDI imaging benchmark dataset for MS1-based lipid annotation tools.
Lars Gruber, Stefan Schmidt, Thomas Enzlein, Carsten Hopf

Gigascience· December 2025

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From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Carsten Hopf

Adv Sci (Weinh)· December 2025

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Nanodroplet Array Platform for Integrated Synthesis and Screening of MEK Inhibitors: a Miniaturized Approach to Early Drug Discovery.
Maximilian Seifermann, Julius Höpfner, Liana Bauer, Divya Varadharajan, Stefan Schmidt, Carsten Hopf

Angew Chem Int Ed Engl· November 2025

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Spatial lipidomics reveals demyelination and remyelination dynamics in the mouse brain.
Mikolaj Opielka, Krzysztof Urbanowicz, Klaudia Konieczna-Wolska, Elisabeth Müller, Oliwier Krajewski, Carsten Hopf

J Lipid Res· November 2025

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The relationship between amyloid-β peptide spectrum and the spastic paraparesis phenotype in autosomal dominant Alzheimer's disease.
Katarzyna Marta Zoltowska, Julia Bandera, Mohamed Belal Hamed, Thomas Enzlein, Carsten Hopf

Alzheimers Res Ther· November 2025

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Microglia-neuron crosstalk through Hex-GM2-MGL2 maintains brain homeostasis.
Maximilian Frosch, Takashi Shimizu, Emile Wogram, Lukas Amann, Lars Gruber, Carsten Hopf

Nature· October 2025

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Reliable Identification of Alpha2u-Globulin and Lysozyme Accumulation in Rat Kidney by Label-Free MALDI Mass Spectrometry Imaging.
Stefania-Alexandra Iakab, Heike Antje Marxfeld, Florian M Richter, Alexander Geisel, Yasemin Ucal, Carsten Hopf

Toxicol Pathol· October 2025

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Novel Multimodal Imaging System for High-Resolution and High-Contrast Tissue Segmentation Based on Chemical Properties.
Björn van Marwick, Felix Lauer, Felix Wühler, Miriam Rittel, Carmen Wängler, Carsten Hopf

Sensors (Basel)· October 2025

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Improving MALDI Mass Spectrometry Imaging Performance: Low-Temperature Thermal Evaporation for Controlled Matrix Deposition and Improved Image Quality.
Toufik Mahamdi, Cristina Gomez Serna, Roger Giné, Jordi Rofes, Shad Arif Mohammed, Carsten Hopf

J Am Soc Mass Spectrom· May 2025

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Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy.
Lars Gruber, Stefan Schmidt, Thomas Enzlein, Huong Giang Vo, Tobias Bausbacher, Carsten Hopf

Nat Commun· May 2025

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Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity.
Marcin Mikołaj Grzybowski, Yasemin Uçal, Angelika Muchowicz, Tomasz Rejczak, Agnieszka Kikulska, Carsten Hopf

Sci Rep· May 2025

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Mass-Guided Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers.
James L Cairns, Johanna Huber, Andrea Lewen, Jessica Jung, Stefan J Maurer, Carsten Hopf

Adv Sci (Weinh)· February 2025

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Exploring the Aβ Plaque Microenvironment in Alzheimer's Disease Model Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer.
Elisabeth Müller, Thomas Enzlein, Dagmar Niemeyer, Livia von Ammon, Katherine Stumpo, Carsten Hopf

Pharmaceuticals (Basel)· February 2025

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TET3 regulates terminal cell differentiation at the metabolic level.
Isabel Mulet, Carmen Grueso-Cortina, Mireia Cortés-Cano, Daniela Gerovska, Guangming Wu, Carsten Hopf

Nat Commun· November 2024

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M2ara: unraveling metabolomic drug responses in whole-cell MALDI mass spectrometry bioassays.
Thomas Enzlein, Alexander Geisel, Carsten Hopf, Stefan Schmidt

Bioinformatics· November 2024

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Label-free assessment of complement-dependent cytotoxicity of therapeutic antibodies via a whole-cell MALDI mass spectrometry bioassay.
Stefan Schmidt, Alexander Geisel, Thomas Enzlein, Björn C Fröhlich, Louise Pritchett, Carsten Hopf

Sci Rep· September 2024

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Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Carsten Hopf

Elife· July 2024

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High-Throughput Miniaturized Synthesis of PROTAC-Like Molecules.
Ye Tian, Maximilian Seifermann, Liana Bauer, Charlotte Luchena, Janne J Wiedmann, Carsten Hopf

Small· June 2024

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Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain.
Thomas Enzlein, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Lucía Chávez-Gutiérrez

Anal Chem· June 2024

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Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.
Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Carsten Hopf

bioRxiv· April 2024

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pyM2aia: Python interface for mass spectrometry imaging with focus on deep learning.
Jonas Cordes, Thomas Enzlein, Carsten Hopf, Ivo Wolf

Bioinformatics· March 2024

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PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma.
Sophie Heuer, Ina Burghaus, Maria Gose, Tobias Kessler, Felix Sahm, Carsten Hopf

BMC Cancer· January 2024

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APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release.
Matthias Koch, Thomas Enzlein, Shu-Yu Chen, Dieter Petit, Sam Lismont, Carsten Hopf

EMBO J· December 2023

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Site-Specific Structural Changes in Long-Term-Stressed Monoclonal Antibody Revealed with DEPC Covalent-Labeling and Quantitative Mass Spectrometry.
Manasi Gaikwad, Florian Richter, Rabea Götz, Aline Dörrbaum, Lena Schumacher, Carsten Hopf

Pharmaceuticals (Basel)· October 2023

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