Publications by authors named "Catherine A Freije"

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The current and future landscape of RNA-based therapies and diagnostics.
Catherine A Freije, Virginia Arechavala-Gomeza

Commun Med (Lond)· November 2025

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Pan-viral ORFs discovery using massively parallel ribosome profiling.
Shira Weingarten-Gabbay, Matthew R Bauer, Alexandra C Stanton, Yingpu Yu, Catherine A Freije

Science· June 2025

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A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist.
Jérémie Le Pen, Gabrielle Paniccia, Volker Kinast, Marcela Moncada-Velez, Alison W Ashbrook, Catherine A Freije

PLoS Biol· September 2024

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Deep mutational scanning of hepatitis B virus reveals a mechanism for cis-preferential reverse transcription.
Yingpu Yu, Maximilian A Kass, Mengyin Zhang, Noor Youssef, Catherine A Freije

Cell· May 2024

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An RNA-based system to study hepatitis B virus replication and evaluate antivirals.
Yingpu Yu, William M Schneider, Maximilian A Kass, Eleftherios Michailidis, Ashley Acevedo, Catherine A Freije

Sci Adv· April 2023

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Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants.
Jon Arizti-Sanz, A'Doriann Bradley, Yibin B Zhang, Chloe K Boehm, Catherine A Freije

Nat Biomed Eng· August 2022

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Equipment-free detection of SARS-CoV-2 and Variants of Concern using Cas13.
Jon Arizti-Sanz, A'Doriann Bradley, Yibin B Zhang, Chloe K Boehm, Catherine A Freije

medRxiv· November 2021

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Detect and destroy: CRISPR-based technologies for the response against viruses.
Catherine A Freije, Pardis C Sabeti

Cell Host Microbe· May 2021

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Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2.
Jon Arizti-Sanz, Catherine A Freije, Alexandra C Stanton, Brittany A Petros, Chloe K Boehm

Nat Commun· November 2020

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Powassan Virus Neuropathology and Genomic Diversity in Patients With Fatal Encephalitis.
Erica Normandin, Isaac H Solomon, Siavash Zamirpour, Jacob Lemieux, Catherine A Freije

Open Forum Infect Dis· October 2020

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Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.
Kayla G Barnes, Anna E Lachenauer, Adam Nitido, Sameed Siddiqui, Robin Gross, Catherine A Freije

Nat Commun· August 2020

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Massively multiplexed nucleic acid detection with Cas13.
Cheri M Ackerman, Cameron Myhrvold, Sri Gowtham Thakku, Catherine A Freije, Hayden C Metsky

Nature· June 2020

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Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2.
Jon Arizti-Sanz, Catherine A Freije, Alexandra C Stanton, Chloe K Boehm, Brittany A Petros

bioRxiv· May 2020

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Programmable Inhibition and Detection of RNA Viruses Using Cas13.
Catherine A Freije, Cameron Myhrvold, Chloe K Boehm, Aaron E Lin, Nicole L Welch

Mol Cell· December 2019

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Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection.
Anne Piantadosi, Catherine A Freije, Christina Gosmann, Simon Ye, Daniel Park

J Virol· January 2019

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Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018.
Katherine J Siddle, Philomena Eromon, Kayla G Barnes, Samar Mehta, Judith U Oguzie, Catherine A Freije

N Engl J Med· November 2018

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Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance.
Brad R Rosenberg, Marion Depla, Catherine A Freije, Denis Gaucher, Sabrina Mazouz

PLoS Pathog· September 2018

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Field-deployable viral diagnostics using CRISPR-Cas13.
Cameron Myhrvold, Catherine A Freije, Jonathan S Gootenberg, Omar O Abudayyeh, Hayden C Metsky

Science· April 2018

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Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
Shen-Ying Zhang, Nathaniel E Clark, Catherine A Freije, Elodie Pauwels, Allison J Taggart

Cell· February 2018

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Genetic Variation at IFNL4 Influences Extrahepatic Interferon-Stimulated Gene Expression in Chronic HCV Patients.
Brad R Rosenberg, Catherine A Freije, Naoko Imanaka, Spencer T Chen, Jennifer L Eitson

J Infect Dis· January 2018

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Genomic epidemiology reveals multiple introductions of Zika virus into the United States.
Nathan D Grubaugh, Jason T Ladner, Moritz U G Kraemer, Gytis Dudas, Amanda L Tan, Catherine A Freije

Nature· June 2017

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Zika virus evolution and spread in the Americas.
Hayden C Metsky, Christian B Matranga, Shirlee Wohl, Stephen F Schaffner, Catherine A Freije

Nature· June 2017

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Nucleic acid detection with CRISPR-Cas13a/C2c2.
Jonathan S Gootenberg, Omar O Abudayyeh, Jeong Wook Lee, Patrick Essletzbichler, Aaron J Dy, Catherine A Freije

Science· April 2017

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Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.
Elana P Simon, Catherine A Freije, Benjamin A Farber, Gadi Lalazar, David G Darcy

Proc Natl Acad Sci U S A· November 2015

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