Publications by authors named "Cathy Paddock"

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Relieving platelet inhibition using a novel bispecific antibody: a novel approach for circumventing the platelet storage lesion.
Alyssa J Moroi, Cathy Paddock, Peter J Newman

J Thromb Haemost· September 2025

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The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function.
Panida Lertkiatmongkol, Cathy Paddock, Debra K Newman, Jieqing Zhu, Michael J Thomas

J Biol Chem· December 2016

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Structural basis for PECAM-1 homophilic binding.
Cathy Paddock, Dongwen Zhou, Panida Lertkiatmongkol, Peter J Newman, Jieqing Zhu

Blood· February 2016

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Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1).
Heng Mei, Jay M Campbell, Cathy M Paddock, Panida Lertkiatmongkol, Michael W Mosesson

J Biol Chem· July 2014

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Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.
Cathy Paddock, Betsy L Lytle, Francis C Peterson, Trudy Holyst, Peter J Newman

Blood· June 2011

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Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.
Jamie R Privratsky, Cathy M Paddock, Oliver Florey, Debra K Newman, William A Muller

J Cell Sci· May 2011

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An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling.
Carmen Bergom, Cathy Paddock, Cunji Gao, Trudy Holyst, Debra K Newman

J Cell Sci· April 2008

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The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).
Ulrich J H Sachs, Cornelia L Andrei-Selmer, Amudhan Maniar, Timo Weiss, Cathy Paddock

J Biol Chem· August 2007

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The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy.
Carmen Bergom, Reema Goel, Cathy Paddock, Cunji Gao, Debra K Newman

Cancer Biol Ther· December 2006

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Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotection.
Caroline T Sardjono, Stacey N Harbour, Jana C Yip, Cathy Paddock, Susheela Tridandapani

Thromb Haemost· December 2006

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Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface.
Brian Boylan, Hong Chen, Vipul Rathore, Cathy Paddock, Michael Salacz

Blood· September 2004

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Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding.
Matthias Maas, Ronggang Wang, Cathy Paddock, Srigiridhar Kotamraju, Balaraman Kalyanaraman

Am J Physiol Heart Circ Physiol· December 2003

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Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes.
Qi-Hong Sun, Chao-Yan Liu, Ronggang Wang, Cathy Paddock, Peter J Newman

Blood· September 2002

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