Publications by authors named "Cecile Beguin"

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Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters.
Thomas A Munro, Xi-Ping Huang, Carmela Inglese, Maria Grazia Perrone, Ashlee Van't Veer

PLoS One· April 2014

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Effects of the anticonvulsant lacosamide compared to valproate and lamotrigine on cocaine-enhanced reward in rats.
Cécile Béguin, David N Potter, William A Carlezon, Thomas Stöhr, Bruce M Cohen

Brain Res· October 2012

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Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity.
Thomas A Munro, Loren M Berry, Ashlee Van't Veer, Cécile Béguin, F Ivy Carroll

BMC Pharmacol· May 2012

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Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues.
Cécile Béguin, Justin Potuzak, Wei Xu, Lee-Yuan Liu-Chen, John M Streicher

Bioorg Med Chem Lett· January 2012

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Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation.
Erica J Melief, Mayumi Miyatake, F Ivy Carroll, Cécile Béguin, William A Carlezon

Mol Pharmacol· November 2011

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Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats.
Christina L Nemeth, Tracie A Paine, Joseph E Rittiner, Cécile Béguin, F Ivy Carroll

Psychopharmacology (Berl)· June 2010

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Kappa-opioid ligands in the study and treatment of mood disorders.
William A Carlezon, Cécile Béguin, Allison T Knoll, Bruce M Cohen

Pharmacol Ther· September 2009

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Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence.
Jacob M Hooker, Thomas A Munro, Cécile Béguin, David Alexoff, Colleen Shea

Neuropharmacology· September 2009

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Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor.
Cécile Béguin, Katharine K Duncan, Thomas A Munro, Douglas M Ho, Wei Xu

Bioorg Med Chem· February 2009

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Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers.
Thomas A Munro, Katharine K Duncan, Wei Xu, Yulin Wang, Lee-Yuan Liu-Chen

Bioorg Med Chem· February 2008

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N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy.
Cécile Béguin, David N Potter, Jennifer A Dinieri, Thomas A Munro, Michele R Richards

J Pharmacol Exp Ther· January 2008

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8-epi-Salvinorin B: crystal structure and affinity at the kappa opioid receptor.
Thomas A Munro, Katharine K Duncan, Richard J Staples, Wei Xu, Lee-Yuan Liu-Chen

Beilstein J Org Chem· January 2007

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Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18).
Cécile Béguin, Michele R Richards, Jian-Guo Li, Yulin Wang, Wei Xu

Bioorg Med Chem Lett· September 2006

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Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats.
William A Carlezon, Cécile Béguin, Jennifer A DiNieri, Michael H Baumann, Michele R Richards

J Pharmacol Exp Ther· January 2006

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Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues.
David Y W Lee, Minsheng He, Leelakrishna Kondaveti, Lee-Yuan Liu-Chen, Zhongze Ma, Cecile Beguin

Bioorg Med Chem Lett· October 2005

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Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues.
David Y W Lee, Vishnu V R Karnati, Minsheng He, Lee-Yuan Liu-Chen, Leelakrishna Kondaveti, Cecile Beguin

Bioorg Med Chem Lett· August 2005

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Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2).
Cécile Béguin, Michele R Richards, Yulin Wang, Yong Chen, Lee-Yuan Liu-Chen

Bioorg Med Chem Lett· June 2005

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N-Substituted amino acid N'-benzylamides: synthesis, anticonvulsant, and metabolic activities.
Cécile Béguin, Arnaud LeTiran, James P Stables, Robert D Voyksner, Harold Kohn

Bioorg Med Chem· June 2004

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Application of predictive QSAR models to database mining: identification and experimental validation of novel anticonvulsant compounds.
Min Shen, Cécile Béguin, Alexander Golbraikh, James P Stables, Harold Kohn

J Med Chem· April 2004

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Functionalized amido ketones: new anticonvulsant agents.
Cécile Béguin, Shridhar V Andurkar, Albert Y Jin, James P Stables, Donald F Weaver

Bioorg Med Chem· September 2003

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