Publications by authors named "Cees Haringa"

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A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies.
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn

Biotechnol Bioeng· December 2025

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Physiological Response of Penicillium chrysogenum to Mimicked Local and Global Perturbations of Substrate and Dissolved Oxygen Gradients at Industrial-Scale.
Yining Chen, Cees Haringa, Zejian Wang, Yingping Zhuang, Guan Wang

Biotechnol Bioeng· June 2025

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An industrial perspective on metabolic responses of Penicillium chrysogenum to periodic dissolved oxygen feast-famine cycles in a scale-down system.
Xueting Wang, Qi Yang, Cees Haringa, Zejian Wang, Ju Chu

Biotechnol Bioeng· October 2024

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Downscaling Industrial-Scale Syngas Fermentation to Simulate Frequent and Irregular Dissolved Gas Concentration Shocks.
Lars Puiman, Eduardo Almeida Benalcázar, Cristian Picioreanu, Henk J Noorman, Cees Haringa

Bioengineering (Basel)· April 2023

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An analysis of organism lifelines in an industrial bioreactor using Lattice-Boltzmann CFD.
Cees Haringa

Eng Life Sci· January 2023

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Microbial lifelines in bioprocesses: From concept to application.
Luisa Blöbaum, Cees Haringa, Alexander Grünberger

Biotechnol Adv· December 2022

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Stochastic parcel tracking in an Euler-Lagrange compartment model for fast simulation of fermentation processes.
Cees Haringa, Wenjun Tang, Henk J Noorman

Biotechnol Bioeng· July 2022

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Developing a Computational Framework To Advance Bioprocess Scale-Up.
Guan Wang, Cees Haringa, Henk Noorman, Ju Chu, Yingping Zhuang

Trends Biotechnol· August 2020

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Coupled metabolic-hydrodynamic modeling enabling rational scale-up of industrial bioprocesses.
Guan Wang, Cees Haringa, Wenjun Tang, Henk Noorman, Ju Chu

Biotechnol Bioeng· March 2020

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Comparative performance of different scale-down simulators of substrate gradients in Penicillium chrysogenum cultures: the need of a biological systems response analysis.
Guan Wang, Junfei Zhao, Cees Haringa, Wenjun Tang, Jianye Xia

Microb Biotechnol· May 2018

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Power input effects on degeneration in prolonged penicillin chemostat cultures: A systems analysis at flux, residual glucose, metabolite, and transcript levels.
Guan Wang, Baofeng Wu, Junfei Zhao, Cees Haringa, Jianye Xia

Biotechnol Bioeng· January 2018

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A 9-pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum.
Wenjun Tang, Amit T Deshmukh, Cees Haringa, Guan Wang, Walter van Gulik

Biotechnol Bioeng· August 2017

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Euler-Lagrange computational fluid dynamics for (bio)reactor scale down: An analysis of organism lifelines.
Cees Haringa, Wenjun Tang, Amit T Deshmukh, Jianye Xia, Matthias Reuss

Eng Life Sci· October 2016

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