Publications by authors named "Celine Cougoule"

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Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy.
Claire Delehouzé, Melodie Mallais, Arnaud Comte, Romain Lucas, Blandine Baratte, Céline Cougoule

Cell Death Discov· November 2025

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Lung organoids as a human system for Mycobacteria infection modeling and drug testing.
Stephen Adonai Leon-Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule

FEBS J· September 2025

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Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis.
Stephen A Leon-Icaza, Maxence Frétaud, Sarahdja Cornélie, Charlotte Bureau, Laure Yatime, Céline Cougoule

Biomed Pharmacother· May 2025

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Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation.
Léana Gorse, Loïc Plessis, Stephen Wearne, Margaux Paradis, Miriam Pinilla, Céline Cougoule

EMBO Mol Med· March 2025

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Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment.
Jin Yan, Jean Monlong, Céline Cougoule, Sonia Lacroix-Lamandé, Agnès Wiedemann

Vet Res· June 2024

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Fluoxetine and Sertraline Potently Neutralize the Replication of Distinct SARS-CoV-2 Variants.
Laura Thümmler, Nadine Beckmann, Carolin Sehl, Matthias Soddemann, Peer Braß, Céline Cougoule

Viruses· March 2024

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EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption.
Miriam Pinilla, Raoul Mazars, Romain Vergé, Leana Gorse, Margaux Paradis, Céline Cougoule

J Exp Med· October 2023

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Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
Stephen Adonai Leon-Icaza, Salimata Bagayoko, Romain Vergé, Nino Iakobachvili, Chloé Ferrand, Céline Cougoule

PLoS Pathog· August 2023

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Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study.
Nicolas Hoertel, Katayoun Rezaei, Marina Sánchez-Rico, Alfonso Delgado-Álvarez, Johannes Kornhuber, Céline Cougoule

Pharmaceuticals (Basel)· August 2023

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A druggable copper-signalling pathway that drives inflammation.
Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, Antoine Versini, Arnaud Mansart, Céline Cougoule

Nature· May 2023

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Establishing 20S Proteasome Genetic, Translational and Post-Translational Status from Precious Biological and Patient Samples with Top-Down MS.
Angelique Sanchez Dafun, Dušan Živković, Stephen Adonai Leon-Icaza, Sophie Möller, Carine Froment, Céline Cougoule

Cells· March 2023

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Risk of Death in Individuals Hospitalized for COVID-19 With and Without Psychiatric Disorders: An Observational Multicenter Study in France.
Nicolas Hoertel, Marina Sánchez-Rico, Pedro de la Muela, Miriam Abellán, Carlos Blanco, Céline Cougoule

Biol Psychiatry Glob Open Sci· January 2023

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Drug repurposing: From the discovery of a useful pharmacological effect to making the treatment available to the patient.
Dominique Deplanque, Christine Fetro, Antoine Ferry, Philippe Lechat, Terence Beghyn, Céline Cougoule

Therapie· January 2023

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[Not Available].
Dominique Deplanque, Christine Fetro, Antoine Ferry, Philippe Lechat, Terence Beghyn, Céline Cougoule

Therapie· January 2023

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Oral supplementation with yeast -glucans improves the resolution of -associated inflammatory responses independently of monocyte/macrophage immune training.
Sarah Walachowski, Koen Breyne, Thomas Secher, Céline Cougoule, Laurence Guzylack-Piriou

Front Immunol· January 2023

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Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model.
David Péricat, Stephen Adonai Leon-Icaza, Marina Sanchez Rico, Christiane Mühle, Iulia Zoicas, Céline Cougoule

Int J Mol Sci· November 2022

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Efficacy and Mode of Action of a Direct Inhibitor of InhA.
Matthéo Alcaraz, Françoise Roquet-Banères, Stephen Adonai Leon-Icaza, Jan Abendroth, Yves-Marie Boudehen, Céline Cougoule

ACS Infect Dis· October 2022

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Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2: Support for the FIASMA Model against COVID-19.
Nicolas Hoertel, Marina Sánchez-Rico, Johannes Kornhuber, Erich Gulbins, Angela M Reiersen, Céline Cougoule

J Clin Med· October 2022

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Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
Rémi Planès, Miriam Pinilla, Karin Santoni, Audrey Hessel, Charlotte Passemar, Céline Cougoule

Mol Cell· July 2022

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Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa.
Karin Santoni, David Pericat, Leana Gorse, Julien Buyck, Miriam Pinilla, Céline Cougoule

PLoS Pathog· July 2022

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Mycobacteria-host interactions in human bronchiolar airway organoids.
Nino Iakobachvili, Stephen Adonai Leon-Icaza, Kèvin Knoops, Norman Sachs, Serge Mazères, Céline Cougoule

Mol Microbiol· March 2022

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Comorbid medical conditions are a key factor to understand the relationship between psychiatric disorders and COVID-19-related mortality: Results from 49,089 COVID-19 inpatients.
Nicolas Hoertel, Marina Sánchez-Rico, Juan José Herrera-Morueco, Pedro de la Muela, Erich Gulbins, Céline Cougoule

Mol Psychiatry· March 2022

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Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19: an observational multicenter study.
Nicolas Hoertel, Marina Sánchez-Rico, Erich Gulbins, Johannes Kornhuber, Alexander Carpinteiro, Céline Cougoule

Transl Psychiatry· March 2022

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Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death.
Claire Delehouzé, Arnaud Comte, Stephen Adonai Leon-Icaza, Céline Cougoule, Marcelle Hauteville

Sci Rep· March 2022

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Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
Salimata Bagayoko, Stephen Adonai Leon-Icaza, Miriam Pinilla, Audrey Hessel, Karin Santoni, Céline Cougoule

PLoS Pathog· September 2021

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