Publications by authors named "Koen Breyne"

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AstroGreen transgenic mouse illuminates the trafficking of astrocyte-derived extracellular vesicles.
Lisa Nieland, Edwina Abou Haidar, David Rufino-Ramos, Shilpa Prabhakar, Youssef Samaha, Koen Breyne

Mol Cell Neurosci· December 2025

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Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunity.
Taral R Lunavat, Lisa Nieland, Sanne M van de Looij, Alexandra J E M de Reus, Charles P Couturier, Koen Breyne

Mol Ther· November 2025

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AAV hamartin gene therapy in a stochastic, cerebral mouse model of tuberous sclerosis type 1.
Edwina Abou Haidar, Shilpa Prabhakar, Alexandra L Geffrey, Mohammed Mahamdeh, Tomeh Tomeh, Koen Breyne

Mol Ther Methods Clin Dev· September 2025

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Engineering of CD63 Enables Selective Extracellular Vesicle Cargo Loading and Enhanced Payload Delivery.
Wataru Obuchi, Ayrton Zargani-Piccardi, Kevin Leandro, David Rufino-Ramos, Emilio Di Lanni, Koen Breyne

J Extracell Vesicles· June 2025

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Extracellular vesicles for the delivery of gene therapy.
Emilio Di Ianni, Wataru Obuchi, Koen Breyne, Xandra O Breakefield

Nat Rev Bioeng· May 2025

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Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of DYT1 allele in a xenograft mouse model.
Katia E Maalouf, Dawn Madison Frederick, Nutan Sharma, Edwina Abou Haidar, Tianhe Xiao, Koen Breyne

Mol Ther Nucleic Acids· March 2025

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Arming AAV9 with a Single-Chain Fragment Variable Antibody Against PD-1 for Systemic Glioblastoma Therapy.
Semer Maksoud, Markus W Schweiger, Elie I Tabet, Tianhe Xiao, Joelle El Hokayem, Koen Breyne

Mol Neurobiol· February 2025

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Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer.
Vamsi Mangena, Rony Chanoch-Myers, Rafaela Sartore, Bruna Paulsen, Simon Gritsch, Koen Breyne

Cancer Discov· February 2025

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Intratumoral gene delivery of 4-1BBL boosts IL-12-triggered anti-glioblastoma immunity.
Taral R Lunavat, Lisa Nieland, Sanne M van de Looij, Alexandra J E M de Reus, Charles P Couturier, Koen Breyne

bioRxiv· February 2025

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CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice.
Lisa Nieland, Anne B Vrijmoet, Isabelle W Jetten, David Rufino-Ramos, Alexandra J E M de Reus, Koen Breyne

Mol Ther· January 2025

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Enhanced mRNA delivery using ultrasound-delivered click reactive anchors.
Emilio Di Ianni, Jueun Jeon, Huiyu Hu, Jeremy M Quintana, Chanseo Lee, Koen Breyne

bioRxiv· January 2025

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Exploring the potential of cell-derived vesicles for transient delivery of gene editing payloads.
Kevin Leandro, David Rufino-Ramos, Koen Breyne, Emilio Di Ianni, Sara M Lopes

Adv Drug Deliv Rev· August 2024

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Glioblastoma extracellular vesicles modulate immune PD-L1 expression in accessory macrophages upon radiotherapy.
Markus W Schweiger, Zohreh Amoozgar, Pierre Repiton, Robert Morris, Semer Maksoud, Koen Breyne

iScience· February 2024

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Roles of extracellular vesicles in glioblastoma: foes, friends and informers.
Taral R Lunavat, Lisa Nieland, Anne B Vrijmoet, Ayrton Zargani-Piccardi, Youssef Samaha, Koen Breyne

Front Oncol· November 2023

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Extracellular communication between brain cells through functional transfer of Cre mRNA mediated by extracellular vesicles.
David Rufino-Ramos, Kevin Leandro, Pedro R L Perdigão, Killian O'Brien, Maria Manuel Pinto, Koen Breyne

Mol Ther· July 2023

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Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged, EV-associated biomarkers.
Katia E Maalouf, Christine A Vaine, Dawn M Frederick, Akiko Yoshinaga, Wataru Obuchi, Koen Breyne

Mol Ther· July 2023

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Engineered EVs designed to target diseases of the CNS.
Lisa Nieland, Shadi Mahjoum, Emily Grandell, Koen Breyne, Xandra O Breakefield

J Control Release· April 2023

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Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis: a proof-of-concept study.
Niels Vander Elst, Julie Bellemans, Jonas Steenbrugge, Chloë Geeroms, Koen Breyne

Vet Res· March 2023

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Oral supplementation with yeast -glucans improves the resolution of -associated inflammatory responses independently of monocyte/macrophage immune training.
Sarah Walachowski, Koen Breyne, Thomas Secher, Céline Cougoule, Laurence Guzylack-Piriou

Front Immunol· January 2023

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Extracellular communication between brain cells through functional transfer of Cre mRNA.
David Rufino-Ramos, Kevin Leandro, Pedro R L Perdigão, Killian O'Brien, Maria Manuel Pinto, Koen Breyne

bioRxiv· January 2023

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Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme.
Asraa Faris Aldoghachi, Ahmed Faris Aldoghachi, Koen Breyne, King-Hwa Ling, Pike-See Cheah

Neuroscience· May 2022

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Exogenous loading of extracellular vesicles, virus-like particles, and lentiviral vectors with supercharged proteins.
Koen Breyne, Stefano Ughetto, David Rufino-Ramos, Shadi Mahjoum, Emily A Grandell

Commun Biol· May 2022

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Using genetically modified extracellular vesicles as a non-invasive strategy to evaluate brain-specific cargo.
David Rufino-Ramos, Sevda Lule, Shadi Mahjoum, Stefano Ughetto, D Cristopher Bragg, Koen Breyne

Biomaterials· February 2022

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The International Society of RNA Nanotechnology and Nanomedicine (ISRNN): The Present and Future of the Burgeoning Field.
Morgan Chandler, Brittany Johnson, Emil Khisamutdinov, Marina A Dobrovolskaia, Joanna Sztuba-Solinska, Koen Breyne

ACS Nano· November 2021

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Enterobactin Deficiency in a Coliform Mastitis Isolate Decreases Its Fitness in a Murine Model: A Preliminary Host-Pathogen Interaction Study.
Niels Vander Elst, Koen Breyne, Jonas Steenbrugge, Amanda Jane Gibson, David George Emslie Smith

Front Vet Sci· November 2020

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