Publications by authors named "Celine Merg"

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Toxicoproteomics reveals an effect of clozapine on autophagy in human liver spheroids.
Catherine Nury, Celine Merg, Yvan Eb-Levadoux, David Bovard, Matthieu Porchet

Toxicol Mech Methods· June 2023

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Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5-week study in A/J mice.
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, Chin Suan Chua, David Sciuscio, Celine Merg

J Appl Toxicol· October 2022

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Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System.
Gabriele Specioso, David Bovard, Filippo Zanetti, Fabio Maranzano, Céline Merg

Bioengineering (Basel)· September 2022

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Assessment of in vitro kinetics and biological impact of nebulized trehalose on human bronchial epithelium.
Anita R Iskandar, Aditya Reddy Kolli, Albert Giralt, Laurent Neau, Maria Fatarova, Celine Merg

Food Chem Toxicol· November 2021

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Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.
Carine Poussin, Marco van der Toorn, Sophie Scheuner, Romain Piault, Athanasios Kondylis, Celine Merg

Arch Toxicol· October 2021

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A 6-month inhalation toxicology study in Apoe mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Ee Tsin Wong, Justyna Szostak, Bjoern Titz, Tom Lee, Sin Kei Wong, Celine Merg

Arch Toxicol· May 2021

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Comparison of the biological impact of aerosol of e-vapor device with MESH® technology and cigarette smoke on human bronchial and alveolar cultures.
Albert Giralt, Anita R Iskandar, Florian Martin, Elisa Moschini, Tomasso Serchi, Celine Merg

Toxicol Lett· February 2021

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Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.
Pedro A Ruiz Castro, Ulrike Kogel, Giuseppe Lo Sasso, Blaine W Phillips, Alain Sewer, Celine Merg

J Inflamm (Lond)· August 2020

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The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.
Giuseppe Lo Sasso, Blaine W Phillips, Alain Sewer, James N D Battey, Athanasios Kondylis, Celine Merg

Sci Rep· March 2020

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Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.
Anita R Iskandar, Filippo Zanetti, Diego Marescotti, Bjorn Titz, Alain Sewer, Celine Merg

Arch Toxicol· November 2019

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A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.
Anita R Iskandar, Filippo Zanetti, Athanasios Kondylis, Florian Martin, Patrice Leroy, Celine Merg

Intern Emerg Med· September 2019

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Corrigendum to "The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product" published in Toxicology in Vitro, Volume 50, August 2018, Pages 95-108.
Marco van der Toorn, Alain Sewer, Diego Marescotti, Stephanie Johne, Karin Baumer, Celine Merg

Toxicol In Vitro· April 2019

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The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.
Marco van der Toorn, Alain Sewer, Diego Marescotti, Stephanie Johne, Karin Baumer, Celine Merg

Toxicol In Vitro· August 2018

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A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.
Blaine W Phillips, Walter K Schlage, Bjoern Titz, Ulrike Kogel, Davide Sciuscio, Celine Merg

Food Chem Toxicol· June 2018

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Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.
Anita R Iskandar, Yannick Martinez, Florian Martin, Walter K Schlage, Patrice Leroy, Celine Merg

Toxicol Res (Camb)· November 2017

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A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.
Anita R Iskandar, Carole Mathis, Walter K Schlage, Stefan Frentzel, Patrice Leroy, Celine Merg

Toxicol In Vitro· March 2017

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3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product.
Anita R Iskandar, Carole Mathis, Florian Martin, Patrice Leroy, Alain Sewer, Celine Merg

ALTEX· February 2017

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Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice.
Ashraf Elamin, Bjoern Titz, Sophie Dijon, Celine Merg, Marcel Geertz

J Proteomics· August 2016

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Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.
Filippo Zanetti, Alain Sewer, Carole Mathis, Anita R Iskandar, Radina Kostadinova, Céline Merg

Chem Res Toxicol· August 2016

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Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.
Sam Ansari, Karine Baumer, Stéphanie Boué, Sophie Dijon, Remi Dulize, Celine Merg

Sci Data· January 2016

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The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.
Marja Talikka, Radina Kostadinova, Yang Xiang, Carole Mathis, Alain Sewer, Celine Merg

Int J Toxicol· September 2015

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Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Maciej Cabanski, Brett Fields, Stephanie Boue, Natalia Boukharov, Hector DeLeon, Celine Merg

Inflamm Res· July 2015

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