Publications by authors named "Chad Groer"

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Intralesional injection of CpG ODNs complexed with glatiramer acetate mitigates systemic cytokine toxicities and synergistically advances checkpoint blockade efficacy.
Huan Gong, J Daniel Griffin, Chad E Groer, Xiaoqing Wu, Mengyue Li

Drug Deliv Transl Res· January 2025

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Glatiramer Acetate Complexes CpG Oligodeoxynucleotides into Nanoparticles and Boosts Their TLR9-Driven Immunity.
Huan Gong, J Daniel Griffin, Chad E Groer, Sa Wu, Grant M Downes

Mol Pharm· December 2024

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Design of a Tumor Binding GMCSF as Intratumoral Immunotherapy of Solid Tumors.
Aparna Raghavachar Chakravarti, Chad E Groer, Huan Gong, Vivian Yudistyra, Marcus Laird Forrest

Mol Pharm· April 2023

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Glatiramer Acetate Complexed with CpG as Intratumoral Immunotherapy in Combination with Anti-PD-1.
Aric Huang, Chad Groer, Ruolin Lu, M Laird Forrest, J Daniel Griffin

Mol Pharm· November 2022

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Glatiramer acetate enhances tumor retention and innate activation of immunostimulants.
Melissa M Pressnall, Aric Huang, Chad E Groer, Sebastian G Huayamares, M Laird Forrest

Int J Pharm· August 2021

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Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors.
Sebastian G Huayamares, Jimmy Y Song, Aric Huang, Samuel R Crowl, Chad E Groer

Macromol Biosci· December 2020

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Intratumoral Cancer Chemotherapy with a Carrier-Based Immunogenic Cell-Death Eliciting Platinum (IV) Agent.
Chad Groer, Ti Zhang, Ruolin Lu, Shuang Cai, Derek Mull

Mol Pharm· November 2020

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Human intratumoral therapy: Linking drug properties and tumor transport of drugs in clinical trials.
Aric Huang, Melissa M Pressnall, Ruolin Lu, Sebastian G Huayamares, J Daniel Griffin, Chad Groer

J Control Release· October 2020

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Formulation and preclinical evaluation of a toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator.
Ruolin Lu, Chad Groer, Peter A Kleindl, K Ryan Moulder, Aric Huang

J Control Release· July 2019

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Injectable Chemotherapy Downstaged Oral Squamous Cell Carcinoma from Nonresectable to Resectable in a Rescue Dog: Diagnosis, Treatment, and Outcome.
Shuang Cai, Ti Zhang, Chad Groer, Melanie Forrest, Daniel Aires

Case Rep Vet Med· October 2018

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Formation of platinum (II) as a six member ring for sustained polymeric delivery.
Sanjeewa N Senadheera, Ti Zhang, Chad E Groer, M Laird Forrest

Eur J Med Chem· August 2017

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Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability.
Rachel Saylor Crowley, Andrew P Riley, Alexander M Sherwood, Chad E Groer, Nirajmohan Shivaperumal

J Med Chem· December 2016

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Phase I-II clinical trial of hyaluronan-cisplatin nanoconjugate in dogs with naturally occurring malignant tumors.
Shuang Cai, Ti Zhang, W C Forrest, Qiuhong Yang, Chad Groer

Am J Vet Res· September 2016

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Hyaluronan-Lysine Cisplatin Drug Carrier for Treatment of Localized Cancers: Pharmacokinetics, Tolerability, and Efficacy in Rodents and Canines.
Ti Zhang, Shuang Cai, Chad Groer, Wai Chee Forrest, Qiuhong Yang

J Pharm Sci· June 2016

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Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues.
Andrew P Riley, Chad E Groer, David Young, Amy W Ewald, Bronwyn M Kivell

J Med Chem· December 2014

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Studies toward the Development of Antiproliferative Neoclerodanes from Salvinorin A.
Tamara Vasiljevik, Chad E Groer, Kurt Lehner, Hernan Navarro, Thomas E Prisinzano

J Nat Prod· August 2014

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Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.
Cullen L Schmid, John M Streicher, Chad E Groer, Thomas A Munro, Lei Zhou

J Biol Chem· August 2013

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Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues.
Cécile Béguin, Justin Potuzak, Wei Xu, Lee-Yuan Liu-Chen, John M Streicher, Chad E Groer

Bioorg Med Chem Lett· January 2012

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Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.
Kirsten M Raehal, Cullen L Schmid, Chad E Groer, Laura M Bohn

Pharmacol Rev· December 2011

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Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.
Chad E Groer, Cullen L Schmid, Alex M Jaeger, Laura M Bohn

J Biol Chem· September 2011

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Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.
Michael A Tarselli, Kirsten M Raehal, Alex K Brasher, John M Streicher, Chad E Groer

Nat Chem· June 2011

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Herkinorin analogues with differential beta-arrestin-2 interactions.
Kevin Tidgewell, Chad E Groer, Wayne W Harding, Anthony Lozama, Matthew Schmidt

J Med Chem· April 2008

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