Publications by authors named "Chad Swanson"

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KHNYN is a manganese-dependent endoribonuclease required for ZAP-mediated antiviral restriction.
Rebecca L Youle, Maria Jose Lista, Emma L Brudenell, Bradley Thompson, Clement Bouton, Chad M Swanson

Nucleic Acids Res· November 2025

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Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN.
Rebecca L Youle, María José Lista, Clement Bouton, Simone Kunzelmann, Harry Wilson, Chad M Swanson

J Biol Chem· April 2025

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Syn-CpG-Spacer: A Panel web app for synonymous recoding of viral genomes with CpG dinucleotides.
Aleksander Sulkowski, Clément Bouton, Chad Swanson

J Open Source Softw· April 2024

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Using Systems Thinking and Complexity Theory to understand and improve Emergency Medicine: Lessons from COVID-19 in a safety net health system.
Evan Rusoja, R Chad Swanson, Mini Swift

J Eval Clin Pract· March 2024

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Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors.
Shabab Chowdhury, Katie A Latham, Andy C Tran, Christopher J Carroll, Richard J Stanton, Chad M Swanson

J Gen Virol· December 2023

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The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.
Michael S Rafii, Reisa A Sperling, Michael C Donohue, Jin Zhou, Claire Roberts, Chad J Swanson

Alzheimers Dement· April 2023

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A combined physiologically-based pharmacokinetic and quantitative systems pharmacology model for modeling amyloid aggregation in Alzheimer's disease.
Hugo Geerts, Mike Walker, Rachel Rose, Silke Bergeler, Piet H van der Graaf, Chad Swanson

CPT Pharmacometrics Syst Pharmacol· April 2023

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Lecanemab for Patients With Early Alzheimer Disease: Bayesian Analysis of a Phase 2b Dose-Finding Randomized Clinical Trial.
Donald A Berry, Shobha Dhadda, Michio Kanekiyo, David Li, Chad J Swanson

JAMA Netw Open· April 2023

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Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins.
Maria Jose Lista, Adam A Witney, Jenna Nichols, Andrew J Davison, Harry Wilson, Chad M Swanson

J Virol· March 2023

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ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease.
Lawrence S Honig, Jerome Barakos, Shobha Dhadda, Michio Kanekiyo, Larisa Reyderman, Chad J Swanson

Alzheimers Dement (N Y)· March 2023

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An assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data.
Harry Bowles, Renata Kabiljo, Ahmad Al Khleifat, Ashley Jones, John P Quinn, Chad M Swanson

Front Bioinform· February 2023

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A Nuclear Export Signal in KHNYN Required for Its Antiviral Activity Evolved as ZAP Emerged in Tetrapods.
Maria J Lista, Mattia Ficarelli, Harry Wilson, Dorota Kmiec, Rebecca L Youle, Chad M Swanson

J Virol· January 2023

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Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease.
Seiichi Hayato, Osamu Takenaka, Sree Harsha Sreerama Reddy, Ishani Landry, Larisa Reyderman, Chad Swanson

CPT Pharmacometrics Syst Pharmacol· December 2022

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The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance.
Maria Jose Lista, Helena Winstone, Harry D Wilson, Adam Dyer, Suzanne Pickering, Chad Swanson

J Virol· December 2022

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Consistency of efficacy results across various clinical measures and statistical methods in the lecanemab phase 2 trial of early Alzheimer's disease.
Shobha Dhadda, Michio Kanekiyo, David Li, Chad J Swanson, Michael Irizarry

Alzheimers Res Ther· December 2022

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Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study.
Eric McDade, Jeffrey L Cummings, Shobha Dhadda, Chad J Swanson, Larisa Reyderman

Alzheimers Res Ther· December 2022

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RetroSnake: A modular pipeline to detect human endogenous retroviruses in genome sequencing data.
Renata Kabiljo, Harry Bowles, Heather Marriott, Ashley R Jones, Clement R Bouton, Chad M Swanson

iScience· November 2022

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Cellular and molecular mechanisms of IMMunE dysfunction and Recovery from SEpsis-related critical illness in adults: An observational cohort study (IMMERSE) protocol paper.
Matthew Fish, Kate Arkless, Aislinn Jennings, Julie Wilson, Michael J Carter, Chad M Swanson

J Intensive Care Soc· August 2022

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TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction.
Rui Pedro Galão, Harry Wilson, Kristina L Schierhorn, Franka Debeljak, Bianca S Bodmer, Chad M Swanson

PLoS Pathog· May 2022

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Correction to: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
Chad J Swanson, Yong Zhang, Shobha Dhadda, Jinping Wang, June Kaplow

Alzheimers Res Ther· May 2022

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Minimal impact of ZAP on lentiviral vector production and transduction efficiency.
Helin Sertkaya, Laura Hidalgo, Mattia Ficarelli, Dorota Kmiec, Adrian W Signell, Chad M Swanson

Mol Ther Methods Clin Dev· December 2021

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S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies.
Dorota Kmiec, María José Lista, Mattia Ficarelli, Chad M Swanson, Stuart J D Neil

PLoS Pathog· October 2021

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Targeted Restriction of Viral Gene Expression and Replication by the ZAP Antiviral System.
Mattia Ficarelli, Stuart J D Neil, Chad M Swanson

Annu Rev Virol· September 2021

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HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4 T Cells Early Postinfection.
Hélène Bauby, Christopher C Ward, Rupert Hugh-White, Chad M Swanson, Reiner Schulz

mBio· June 2021

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