Publications by authors named "Chaim Gilon"

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RETRACTED: Naamneh et al. Structure-Activity Relationship of Synthetic Linear KTS-Peptides Containing Meta-Aminobenzoic Acid as Antagonists of α1β1 Integrin with Anti-Angiogenic and Melanoma Anti-Tumor Activities. 2024, , 549.
Majdi Saleem Naamneh, Tatjana Momic, Michal Klazas, Julius Grosche, Johannes A Eble, Chaim Gilon

Pharmaceuticals (Basel)· September 2025

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Application of Lipophilic Prodrug Charge Masking Strategy to Obtain Novel, Potential Oxytocin Prodrugs.
Agata Gitlin-Domagalska, Anna Olejnik, Jarosław Ruczyński, Dominika Starego, Natalia Ptaszyńska, Chaim Gilon

Int J Mol Sci· May 2025

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Anti-Inflammatory Effects of Clarstatin, a Shared-Epitope-Antagonistic Cyclic Peptide, on Experimental Autoimmune Uveitis in Mice.
Shira Merzbach, Adi Schumacher-Klinger, Michal Klazas, Amnon Hoffman, Philip Lazarovici, Chaim Gilon

Invest Ophthalmol Vis Sci· January 2025

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Treatment with αvβ3-integrin-specific 29P attenuates pressure-overload induced cardiac remodelling after transverse aortic constriction in mice.
Alexandra Njegić, Lina Laid, Min Zi, Eleni Maniati, Jun Wang, Chaim Gilon

J Mol Cell Cardiol Plus· June 2024

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Development of Clarstatin, a Novel Drug Lead for the Therapy of Autoimmune Uveitis.
Shira Merzbach, Amnon Hoffman, Philip Lazarovici, Chaim Gilon, Radgonde Amer

Pharmaceutics· May 2024

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PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs.
Jeetendra Kumar Nag, Amnon Hoffman, Chaim Gilon, Beatrice Uziely, Rachel Bar-Shavit

Oncoscience· April 2024

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RETRACTED: Structure-Activity Relationship of Synthetic Linear KTS-Peptides Containing Meta-Aminobenzoic Acid as Antagonists of α1β1 Integrin with Anti-Angiogenic and Melanoma Anti-Tumor Activities.
Majdi Saleem Naamneh, Tatjana Momic, Michal Klazas, Julius Grosche, Johannes A Eble, Chaim Gilon

Pharmaceuticals (Basel)· April 2024

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Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis.
Mladena Glavaš, Agata Gitlin-Domagalska, Natalia Ptaszyńska, Dominika Starego, Sylwia Freza, Chaim Gilon

Molecules· November 2023

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PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design.
Jeetendra Kumar Nag, Hodaya Malka, Shoshana Sedley, Priyanga Appasamy, Tatyana Rudina, Chaim Gilon

Mol Cancer Ther· September 2022

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Synthesis and Pharmacological Characterization of Visabron, a Backbone Cyclic Peptide Dual Antagonist of α4β1 (VLA-4)/α9β1 Integrin for Therapy of Multiple Sclerosis.
Chaim Gilon, Michal Klazas, Adi Lahiani, Adi Schumacher-Klinger, Shira Merzbach

JACS Au· December 2021

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Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults.
Chaim Gilon, Agata Gitlin-Domagalska, Adi Lahiani, Shiran Yehoshua-Alshanski, Adi Shumacher-Klinger, Dan Gilon

Peptides· December 2020

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Cyclizing Painkillers: Development of Backbone-Cyclic TAPS Analogs.
Alaa Talhami, Avi Swed, Shmuel Hess, Oded Ovadia, Sarit Greenberg, Chaim Gilon

Front Chem· November 2020

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Deciphering Direct and Indirect Effects of Neurokinin B and GnRH in the Brain-Pituitary Axis of Tilapia.
Naama Mizrahi, Chaim Gilon, Ishwar Atre, Satoshi Ogawa, Ishwar S Parhar

Front Endocrinol (Lausanne)· July 2019

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The tripartite mechanism as the basis for a biochemical memory engram.
Gerard Marx, Chaim Gilon

J Integr Neurosci· June 2019

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Myristoylation Confers Oral Bioavailability and Improves the Bioactivity of c(MyD 4-4), a Cyclic Peptide Inhibitor of MyD88.
Shira Dishon, Adi Schumacher-Klinger, Chaim Gilon, Amnon Hoffman, Gabriel Nussbaum

Mol Pharm· April 2019

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Orally Active Peptides: Is There a Magic Bullet?
Andreas F B Räder, Michael Weinmüller, Florian Reichart, Adi Schumacher-Klinger, Shira Merzbach, Chaim Gilon

Angew Chem Int Ed Engl· October 2018

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Conversion of Protein Active Regions into Peptidomimetic Therapeutic Leads Using Backbone Cyclization and Cycloscan - How to Do it Yourself!
Samuel J S Rubin, Yftah Tal-Gan, Chaim Gilon, Nir Qvit

Curr Top Med Chem· August 2018

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Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Adi Schumacher-Klinger, Joseph Fanous, Shira Merzbach, Michael Weinmüller, Florian Reichart, Chaim Gilon

Mol Pharm· August 2018

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Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88.
Shira Dishon, Adi Schumacher, Joseph Fanous, Alaa Talhami, Ibrahim Kassis, Chaim Gilon

Sci Rep· June 2018

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Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3.
Michael Weinmüller, Florian Rechenmacher, Udaya Kiran Marelli, Florian Reichart, Tobias G Kapp, Chaim Gilon

Angew Chem Int Ed Engl· December 2017

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Oxytocin-Monolayer-Based Impedimetric Biosensor for Zinc and Copper Ions.
Kiran Kumar Tadi, Israel Alshanski, Evgeniy Mervinetsky, Gerard Marx, Panayiota Petrou, Chaim Gilon

ACS Omega· December 2017

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DMAP-assisted sulfonylation as an efficient step for the methylation of primary amine motifs on solid support.
Johnny N Naoum, Koushik Chandra, Dorit Shemesh, R Benny Gerber, Chaim Gilon

Beilstein J Org Chem· May 2017

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Superiority of the S,S conformation in diverse pharmacological processes: Intestinal transport and entry inhibition activity of novel anti-HIV drug lead.
Joseph Fanous, Avi Swed, Salim Joubran, Mattan Hurevich, Elena Britan-Rosich, Chaim Gilon

Int J Pharm· November 2015

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cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .
Udaya Kiran Marelli, Oded Ovadia, Andreas Oliver Frank, Jayanta Chatterjee, Chaim Gilon

Chemistry· October 2015

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Shared epitope-antagonistic ligands: a new therapeutic strategy in mice with erosive arthritis.
Song Ling, Ying Liu, Jiaqi Fu, Alessandro Colletta, Chaim Gilon

Arthritis Rheumatol· May 2015

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