Publications by authors named "Gabriel Nussbaum"

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Therapeutic potential of garlic, aged garlic extract and garlic‑derived compounds on pancreatic cancer (Review).
Hiromichi Kawasaki, Gabriel Nussbaum

Biomed Rep· March 2025

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Anti-Inflammatory Effects of Clarstatin, a Shared-Epitope-Antagonistic Cyclic Peptide, on Experimental Autoimmune Uveitis in Mice.
Shira Merzbach, Adi Schumacher-Klinger, Michal Klazas, Amnon Hoffman, Philip Lazarovici, Gabriel Nussbaum

Invest Ophthalmol Vis Sci· January 2025

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CD47 and thrombospondin-1 contribute to immune evasion by .
Sarah Angabo, Karthikeyan Pandi, Keren David, Orit Steinmetz, Hasnaa Makkawi, Gabriel Nussbaum

Proc Natl Acad Sci U S A· November 2024

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Oral bacteria accelerate pancreatic cancer development in mice.
Elias Saba, Maria Farhat, Alaa Daoud, Arin Khashan, Esther Forkush, Gabriel Nussbaum

Gut· April 2024

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Porphyromonas gingivalis induction of TLR2 association with Vinculin enables PI3K activation and immune evasion.
Karthikeyan Pandi, Sarah Angabo, Jeba Gnanasekaran, Hasnaa Makkawi, Luba Eli-Berchoer, Gabriel Nussbaum

PLoS Pathog· April 2023

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TNFα expression by Porphyromonas gingivalis-stimulated macrophages relies on Sirt1 cleavage.
Sai R K Meka, Tahsin Younis, Eli Reich, Jinan Elayyan, Ashok Kumar, Gabriel Nussbaum

J Periodontal Res· June 2021

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The cationic liposome CCS/C adjuvant induces immunity to influenza independently of the adaptor protein MyD88.
Orli Even-Or, Shani Avniel-Polak, Yechezkel Barenholz, Gabriel Nussbaum

Hum Vaccin Immunother· December 2020

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Intracellular Promotes the Tumorigenic Behavior of Pancreatic Carcinoma Cells.
JebaMercy Gnanasekaran, Adi Binder Gallimidi, Elias Saba, Karthikeyan Pandi, Luba Eli Berchoer, Gabriel Nussbaum

Cancers (Basel)· August 2020

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Myd88 plays a major role in the keratinocyte response to infection with Porphyromonas gingivalis.
David Polak, Asaf Zigron, Luba Eli-Berchoer, Lior Shapira, Gabriel Nussbaum

J Periodontal Res· August 2019

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Myristoylation Confers Oral Bioavailability and Improves the Bioactivity of c(MyD 4-4), a Cyclic Peptide Inhibitor of MyD88.
Shira Dishon, Adi Schumacher-Klinger, Chaim Gilon, Amnon Hoffman, Gabriel Nussbaum

Mol Pharm· April 2019

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Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88.
Shira Dishon, Adi Schumacher, Joseph Fanous, Alaa Talhami, Ibrahim Kassis, Gabriel Nussbaum

Sci Rep· June 2018

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Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88.
Hasnaa Makkawi, Shifra Hoch, Elia Burns, Kavita Hosur, George Hajishengallis, Gabriel Nussbaum

Front Cell Infect Microbiol· April 2018

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Syndecan-1 deficiency promotes tumor growth in a murine model of colitis-induced colon carcinoma.
Adi Binder Gallimidi, Gabriel Nussbaum, Esther Hermano, Barak Weizman, Amichay Meirovitz

PLoS One· September 2017

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Oral fibroblasts modulate the macrophage response to bacterial challenge.
Rinat Tzach-Nahman, Rizan Nashef, Omer Fleissig, Aharon Palmon, Lior Shapira, Gabriel Nussbaum

Sci Rep· September 2017

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Oral infection with Porphyromonas gingivalis induces peri-implantitis in a murine model: Evaluation of bone loss and the local inflammatory response.
Rinat Tzach-Nahman, Gabriel Mizraji, Lior Shapira, Gabriel Nussbaum, Asaf Wilensky

J Clin Periodontol· July 2017

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Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway.
Yael Litvak, Shir Sharon, Meirav Hyams, Li Zhang, Simi Kobi, Gabriel Nussbaum

PLoS Pathog· July 2017

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Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice.
Shira Dishon, Shmuel J Cohen, Irun R Cohen, Gabriel Nussbaum

Front Immunol· May 2017

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GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa.
Maria Nassar, Yaara Tabib, Tal Capucha, Gabriel Mizraji, Tsipora Nir, Gabriel Nussbaum

Proc Natl Acad Sci U S A· January 2017

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Porphyromonas gingivalis Promotes Unrestrained Type I Interferon Production by Dysregulating TAM Signaling via MYD88 Degradation.
Gabriel Mizraji, Maria Nassar, Hadas Segev, Hafiz Sharawi, Luba Eli-Berchoer, Gabriel Nussbaum

Cell Rep· January 2017

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CX3CR1hi Monocyte/Macrophages Support Bacterial Survival and Experimental Infection-Driven Bone Resorption.
Orit Steinmetz, Shifra Hoch, Shani Avniel-Polak, Keren Gavish, Luba Eli-Berchoer, Gabriel Nussbaum

J Infect Dis· May 2016

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From bedside to the bench: uncovering the role of a T-cell protein in protecting CTLA-4.
Gabriel Nussbaum

Oral Dis· May 2016

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Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading to macrophage hyporesponsiveness to bacterial infection.
Asaf Wilensky, Rinat Tzach-Nahman, Jan Potempa, Lior Shapira, Gabriel Nussbaum

J Innate Immun· December 2015

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Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model.
Adi Binder Gallimidi, Stuart Fischman, Brurya Revach, Raanan Bulvik, Alina Maliutina, Gabriel Nussbaum

Oncotarget· September 2015

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Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme.
Esther Hermano, Amichay Meirovitz, Karen Meir, Gabriel Nussbaum, Limor Appelbaum

J Natl Cancer Inst· December 2014

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Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis.
Tomoki Maekawa, Jennifer L Krauss, Toshiharu Abe, Ravi Jotwani, Martha Triantafilou, Gabriel Nussbaum

Cell Host Microbe· June 2014

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