Publications by authors named "Chaim O Jacob"

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Lupus-prone NZM2328 mice exhibit enhanced UV-induced myeloid cell recruitment and activation in a type I interferon dependent manner.
Mitra P Maz, Alayka L Reddy, Celine C Berthier, Lam C Tsoi, Deborah J Colesa, Chaim O Jacob

J Autoimmun· December 2024

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Context-dependent induction of autoimmunity by TNF signaling deficiency.
Tam D Quach, Weiqing Huang, Ranjit Sahu, Catherine Mm Diadhiou, Chirag Raparia, Chaim O Jacob

JCI Insight· March 2022

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New Endothelial Mechanisms in Glomerular (Patho)biology and Proteinuria Development Captured by Intravital Multiphoton Imaging.
Georgina Gyarmati, Chaim O Jacob, János Peti-Peterdi

Front Med (Lausanne)· October 2021

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Inhibition of B cell activation following co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice.
Seung Y Chu, Erik Pong, Christine Bonzon, Ning Yu, Chaim O Jacob

J Transl Autoimmun· December 2020

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On the genetics and immunopathogenesis of COVID-19.
Chaim Oscar Jacob

Clin Immunol· November 2020

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Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis.
Hiroyuki Kadoya, Ning Yu, Ina Maria Schiessl, Anne Riquier-Brison, Georgina Gyarmati, Chaim O Jacob

JCI Insight· October 2020

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Development of Murine Systemic Lupus Erythematosus in the Absence of BAFF.
William Stohl, Ning Yu, Samantha Chalmers, Chaim Putterman, Chaim O Jacob

Arthritis Rheumatol· February 2020

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Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells.
Sonya J Wolf, Shannon N Estadt, Jonathan Theros, Tyson Moore, Jason Ellis, Chaim O Jacob

J Autoimmun· September 2019

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Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice.
William Stohl, Ning Yu, Samantha A Chalmers, Chaim Putterman, Chaim O Jacob

Lupus Sci Med· February 2019

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Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
Ken B Hanscombe, David L Morris, Janelle A Noble, Alexander T Dilthey, Philip Tombleson, Chaim O Jacob

Hum Mol Genet· November 2018

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TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.
Sonya J Wolf, Jonathan Theros, Tammi J Reed, Jianhua Liu, Irina L Grigorova, Chaim O Jacob

J Immunol· July 2018

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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
Zubin H Patel, Xiaoming Lu, Daniel Miller, Carmy R Forney, Joshua Lee, Chaim O Jacob

Hum Mol Genet· July 2018

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Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice.
Chaim O Jacob, Ning Yu, Dae-Goon Yoo, Lizet J Perez-Zapata, Emilia Alina Barbu

Arthritis Rheumatol· August 2017

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Transancestral mapping and genetic load in systemic lupus erythematosus.
Carl D Langefeld, Hannah C Ainsworth, Deborah S Cunninghame Graham, Jennifer A Kelly, Mary E Comeau, Chaim O Jacob

Nat Commun· July 2017

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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Yun Deng, Jian Zhao, Daisuke Sakurai, Andrea L Sestak, Vadim Osadchiy, Chaim O Jacob

Ann Rheum Dis· November 2016

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Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Christopher J Lessard, Satria Sajuthi, Jian Zhao, Kwangwoo Kim, John A Ice, Chaim O Jacob

Arthritis Rheumatol· May 2016

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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Marta E Alarcón-Riquelme, Julie T Ziegler, Julio Molineros, Timothy D Howard, Andrés Moreno-Estrada, Chaim O Jacob

Arthritis Rheumatol· April 2016

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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Chaim O Jacob

Elife· February 2016

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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
Jian Zhao, Hui Wu, Carl D Langefeld, Kenneth M Kaufman, Jennifer A Kelly, Chaim O Jacob

Clin Immunol· December 2015

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Erratum: IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.
Richard T Strait, Monica T Posgai, Ashley Mahler, Nathaniel Barasa, Chaim O Jacob

Nature· October 2015

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Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors.
Chaim O Jacob, Ning Yu, Vishal Sindhava, Michael P Cancro, Rahul D Pawar

Arthritis Rheumatol· September 2015

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Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation affects the structure of NADPH oxidase complex.
Don L Armstrong, Miriam Eisenstein, Raphael Zidovetzki, Chaim O Jacob

J Biol Chem· May 2015

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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Xiaoming Lu, Erin E Zoller, Matthew T Weirauch, Zhiguo Wu, Bahram Namjou, Chaim O Jacob

Am J Hum Genet· May 2015

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Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR.
Hiromi Kubagawa, Michael C Carroll, Chaim O Jacob, Karl S Lang, Kyeong-Hee Lee

J Immunol· May 2015

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Lupus risk variants in the PXK locus alter B-cell receptor internalization.
Samuel E Vaughn, Corinne Foley, Xiaoming Lu, Zubin H Patel, Erin E Zoller, Chaim O Jacob

Front Genet· January 2015

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