Publications by authors named "Chandran Anandhakumar"

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Systems Biology and Functional Assessments of Human iPSC-Cardiomyocyte Models of Insulin Resistance Capture Key Hallmarks of Diabetic Cardiomyopathy.
Ryan D Carter, Ujang Purnama, Marcos Castro-Guarda, Claudia N Montes-Aparicio, Anandhakumar Chandran

Diabetes· November 2025

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MLX plays a key role in lipid and glucose metabolism in humans: Evidence from in vitro and in vivo studies.
Shilpa R Nagarajan, Eilidh J Livingstone, Thomas Monfeuga, Lara C Lewis, Shahul Hameed Liyakath Ali, Anandhakumar Chandran

Metabolism· July 2023

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Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice.
Mauricio D Dorfman, Thomas Monfeuga, Susan J Melhorn, Jenny E Kanter, Jeremy M Frey, Anandhakumar Chandran

Am J Physiol Endocrinol Metab· May 2023

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Hepatocyte mARC1 promotes fatty liver disease.
Lara C Lewis, Lingyan Chen, L Shahul Hameed, Robert R Kitchen, Cyrielle Maroteau, Anandhakumar Chandran

JHEP Rep· May 2023

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RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons.
Sefan Asamitsu, Yasushi Yabuki, Kazuya Matsuo, Moe Kawasaki, Yuki Hirose, Anandhakumar Chandran

Sci Adv· February 2023

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Decitabine increases neoantigen and cancer testis antigen expression to enhance T-cell-mediated toxicity against glioblastoma.
Ruichong Ma, Margarida Rei, Isaac Woodhouse, Katherine Ferris, Sophie Kirschner, Anandhakumar Chandran

Neuro Oncol· December 2022

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NMDA Receptor Antagonists Increase the Release of GLP-1 From Gut Endocrine Cells.
Malgorzata Cyranka, Thomas Monfeuga, Natascia Vedovato, Chelsea M Larabee, Anandhakumar Chandran

Front Pharmacol· April 2022

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Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection.
Jingfei Cheng, Paulina Siejka-Zielińska, Yibin Liu, Anandhakumar Chandran, Skirmantas Kriaucionis

Nucleic Acids Res· July 2021

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Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome.
Jason Lin, Kiriko Hiraoka, Takayoshi Watanabe, Tony Kuo, Yoshinao Shinozaki, Anandhakumar Chandran

PLoS One· June 2017

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Targeting 24 bp within Telomere Repeat Sequences with Tandem Tetramer Pyrrole-Imidazole Polyamide Probes.
Yusuke Kawamoto, Asuka Sasaki, Anandhakumar Chandran, Kaori Hashiya, Satoru Ide

J Am Chem Soc· October 2016

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Genome-Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High-Throughput Sequencing.
Anandhakumar Chandran, Junetha Syed, Yue Li, Shinsuke Sato, Toshikazu Bando

Chembiochem· October 2016

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Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.
Gengo Kashiwazaki, Anandhakumar Chandran, Sefan Asamitsu, Takashi Kawase, Yusuke Kawamoto

Chembiochem· September 2016

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Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit.
Yoshito Sawatani, Gengo Kashiwazaki, Anandhakumar Chandran, Sefan Asamitsu, Chuanxin Guo

Bioorg Med Chem· August 2016

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Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing.
Anandhakumar Chandran, Junetha Syed, Rhys D Taylor, Gengo Kashiwazaki, Shinsuke Sato

Nucleic Acids Res· May 2016

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Identification of Sequence Specificity of 5-Methylcytosine Oxidation by Tet1 Protein with High-Throughput Sequencing.
Seiichiro Kizaki, Anandhakumar Chandran, Hiroshi Sugiyama

Chembiochem· March 2016

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Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates.
Rhys D Taylor, Anandhakumar Chandran, Gengo Kashiwazaki, Kaori Hashiya, Toshikazu Bando

Chemistry· October 2015

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A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts.
Junetha Syed, Anandhakumar Chandran, Ganesh N Pandian, Junichi Taniguchi, Shinsuke Sato

Chembiochem· July 2015

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A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network.
Le Han, Ganesh N Pandian, Anandhakumar Chandran, Shinsuke Sato, Junichi Taniguchi

Angew Chem Int Ed Engl· July 2015

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Advancing small-molecule-based chemical biology with next-generation sequencing technologies.
Chandran Anandhakumar, Seiichiro Kizaki, Toshikazu Bando, Ganesh N Pandian, Hiroshi Sugiyama

Chembiochem· January 2015

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Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts.
Ganesh N Pandian, Shinsuke Sato, Chandran Anandhakumar, Junichi Taniguchi, Kazuhiro Takashima

ACS Chem Biol· December 2014

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Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine.
Chandran Anandhakumar, Yue Li, Seiichiro Kizaki, Ganesh N Pandian, Kaori Hashiya

Chembiochem· December 2014

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Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide.
Junetha Syed, Ganesh N Pandian, Shinsuke Sato, Junichi Taniguchi, Anandhakumar Chandran

Chem Biol· October 2014

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Alteration of epigenetic program to recover memory and alleviate neurodegeneration: prospects of multi-target molecules.
Ganesh N Pandian, Rhys D Taylor, Syed Junetha, Abhijit Saha, Chandran Anandhakumar

Biomater Sci· August 2014

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Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts.
Ganesh N Pandian, Junichi Taniguchi, Syed Junetha, Shinsuke Sato, Le Han, Chandran AnandhaKumar

Sci Rep· January 2014

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A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell.
Le Han, Ganesh N Pandian, Syed Junetha, Shinsuke Sato, Chandran Anandhakumar

Angew Chem Int Ed Engl· December 2013

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