Publications by authors named "Charles Awortwe"

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CRISPR/Cas9-induced knockout reveals the role of ABCB1 in the response to temozolomide, carmustine and lomustine in glioblastoma multiforme.
Lena Radtke, Aleksandra Majchrzak-Celińska, Charles Awortwe, Inga Vater, Inga Nagel

Pharmacol Res· November 2022

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Aspalathin-rich green rooibos tea in combination with glyburide and atorvastatin enhances lipid metabolism in a mouse model.
Oelfah Patel, Christo J F Muller, Elizabeth Joubert, Bernd Rosenkranz, Johan Louw, Charles Awortwe

Front Clin Diabetes Healthc· October 2022

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Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice.
Oelfah Patel, Christo J F Muller, Elizabeth Joubert, Bernd Rosenkranz, Johan Louw, Charles Awortwe

PLoS One· October 2021

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Interaction of Phytocompounds of with ABCB1 and ABCG2 Efflux Transporters.
Charles Awortwe, Henrike Bruckmueller, Meike Kaehler, Ingolf Cascorbi

Mol Pharm· April 2021

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Turning Up the Volume for Precision Herbal Medicine in Africa in an Era of COVID-19 and Planetary Biodiversity Loss.
Nicholas Ekow Thomford, Ewura Seidu Yahaya, Martins Ekor, Charles Awortwe

OMICS· December 2020

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Meta-analysis on outcome-worsening comorbidities of COVID-19 and related potential drug-drug interactions.
Charles Awortwe, Ingolf Cascorbi

Pharmacol Res· November 2020

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Herbal supplements interactions with oral oestrogen-based contraceptive metabolism and transport.
Nokulunga Hlengwa, Christo J F Muller, Albertus K Basson, Sandra Bowles, Johan Louw, Charles Awortwe

Phytother Res· July 2020

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Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats.
Oelfah Patel, Christo J F Muller, Elizabeth Joubert, Bernd Rosenkranz, Malcolm J C Taylor, Charles Awortwe

Front Pharmacol· October 2019

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Interaction of herbal products with prescribed medications: A systematic review and meta-analysis.
Charles Awortwe, Henrike Bruckmueller, Ingolf Cascorbi

Pharmacol Res· March 2019

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MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2.
Charles Awortwe, Meike Kaehler, Bernd Rosenkranz, Ingolf Cascorbi, Henrike Bruckmueller

Xenobiotica· October 2018

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Critical evaluation of causality assessment of herb-drug interactions in patients.
Charles Awortwe, Memela Makiwane, Helmuth Reuter, Christo Muller, Johan Louw

Br J Clin Pharmacol· April 2018

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Inhibitory Interactions of Aspalathus linearis (Rooibos) Extracts and Compounds, Aspalathin and Z-2-(β-d-Glucopyranosyloxy)-3-phenylpropenoic Acid, on Cytochromes Metabolizing Hypoglycemic and Hypolipidemic Drugs.
Oelfah Patel, Christo Muller, Elizabeth Joubert, Johan Louw, Bernd Rosenkranz, Charles Awortwe

Molecules· November 2016

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In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities.
Charles Awortwe, Vamshi K Manda, Cristina Avonto, Shabana I Khan, Ikhlas A Khan

Drug Metab Lett· April 2016

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Inhibition of CYP2B6 by Medicinal Plant Extracts: Implication for Use of Efavirenz and Nevirapine-Based Highly Active Anti-Retroviral Therapy (HAART) in Resource-Limited Settings.
Nicholas E Thomford, Charles Awortwe, Kevin Dzobo, Faustina Adu, Denis Chopera

Molecules· February 2016

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Toxicological assessment of polyhexamethylene biguanide for water treatment.
Isaac J Asiedu-Gyekye, Abdulai Seidu Mahmood, Charles Awortwe, Alexander K Nyarko

Interdiscip Toxicol· December 2015

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A preliminary safety evaluation of polyhexamethylene guanidine hydrochloride.
Isaac Julius Asiedu-Gyekye, Seidu Abdulai Mahmood, Charles Awortwe, Alexander Kwadwo Nyarko

Int J Toxicol· September 2015

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Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway.
Charles Awortwe, Vamshi K Manda, Cristina Avonto, Shabana I Khan, Ikhlas A Khan

Xenobiotica· March 2015

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Application of Caco-2 cell line in herb-drug interaction studies: current approaches and challenges.
Charles Awortwe, P S Fasinu, B Rosenkranz

J Pharm Pharm Sci· December 2014

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Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents.
Vamshi K Manda, Olivia R Dale, Charles Awortwe, Zulfiqar Ali, Ikhlas A Khan

Front Pharmacol· August 2014

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Inhibition of major drug metabolizing CYPs by common herbal medicines used by HIV/AIDS patients in Africa-- implications for herb-drug interactions.
Charles Awortwe, Patrick J Bouic, Collen M Masimirembwa, Bernd Rosenkranz

Drug Metab Lett· July 2014

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Short-term administration of an aqueous extract of kalanchoe integra var. crenata (Andr.) Cuf leaves produces no major organ damage in Sprague-Dawley rats.
Isaac J Asiedu-Gyekye, Daniel A Antwi, Charles Awortwe, Benoit Banga N'guessan, Alexander K Nyarko

J Ethnopharmacol· February 2014

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