Publications by authors named "Charles Cohen"

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Metabolic and Redox Pathway Dysregulation in HIV-Associated Coronary Endothelial Dysfunction: Insights into Early-Phase HIV Vascular Dysfunction.
Kshipra S Keole, Syed Bukhari, Anum Minhas, Charles D Cohen, Amelia Wallace

bioRxiv· December 2025

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Characterising online gamblers exceeding financial risk thresholds in the UK: A retrospective analysis using open banking data.
Kasra Ghaharian, Mana Azizsoltani, Charles Cohen, Piyush Puranik, Bernardo Chagas

Public Health· December 2025

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GSNOR deletion differentially alters age-related cardiac function in a sex-dependent manner.
Obialunanma V Ebenebe, Raihan Kabir, Allison Booher, Haley Garbus, Charles D Cohen

Am J Physiol Heart Circ Physiol· December 2025

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Maternal dietary fibre intake results in sex-specific single-cell molecular changes in the heart of the offspring.
Chaoran Yang, Hamdi A Jama, Malathi S I Dona, Gabriella E Farrugia, Crisdion Krstevski, Charles D Cohen

Clin Sci (Lond)· November 2025

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CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.
Marcelo M Rodriguez, Debashree Chatterjee, Johanna Guerry, Anne-Marie Patenaude, Charles C H Cohen

Proc Natl Acad Sci U S A· June 2025

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The venom of spider contains a natural huwentoxin-IV analogue with unexpected improved analgesic potential.
Aurélie Antunes, Jérôme Montnach, Kuldip Khakh, Ludivine Lopez, Baptiste Thomas, Charles J Cohen

Front Pharmacol· April 2025

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Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na1.7.
Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, Abid Hasan, Michael S Wilson, Charles J Cohen

Bioorg Med Chem Lett· February 2025

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The contribution of Na1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na1.6 gain-of-function (GOF) mouse seizure control.
James P Johnson, Thilo Focken, Parisa Karimi Tari, Celine Dube, Samuel J Goodchild, Charles J Cohen

Br J Pharmacol· October 2024

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Maternal Diet and Gut Microbiota Influence Predisposition to Cardiovascular Disease in Offspring.
Hamdi A Jama, Malathi S I Dona, Evany Dinakis, Michael Nakai, Madeleine R Paterson, Charles D Cohen

Circ Res· August 2024

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B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure.
Jana P Lovell, Carolina Duque, Sylvie Rousseau, Aashik Bhalodia, Kevin Bermea, Charles D Cohen

bioRxiv· June 2024

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B cell-mediated antigen presentation promotes adverse cardiac remodeling in chronic heart failure.
Jana P Lovell, Carolina Duque, Sylvie Rousseau, Aashik Bhalodia, Kevin Bermea, Charles D Cohen

Res Sq· June 2024

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Myocardial B cells have specific gene expression and predicted interactions in dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy.
Kevin C Bermea, Carolina Duque, Charles D Cohen, Aashik Bhalodia, Sylvie Rousseau

Front Immunol· May 2024

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Molecular Pharmacology of Selective Na1.6 and Dual Na1.6/Na1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo.
Samuel J Goodchild, Noah Gregory Shuart, Aaron D Williams, Wenlei Ye, R Ryley Parrish, Charles J Cohen

ACS Chem Neurosci· March 2024

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Myocardial B cells have specific gene expression and predicted interactions in Dilated Cardiomyopathy and Arrhythmogenic Right Ventricular Cardiomyopathy.
Kevin C Bermea, Carolina Duque, Charles D Cohen, Aashik Bhalodia, Sylvie Rousseau

bioRxiv· January 2024

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Mapping the cellular and molecular landscape of cardiac non-myocytes in murine diabetic cardiomyopathy.
Charles D Cohen, Miles J De Blasio, Gabriella E Farrugia, Malathi S I Dona, Ian Hsu

iScience· October 2023

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Structure-function relationship of new peptides activating human Na1.1.
Ludivine Lopez, Stephan De Waard, Hervé Meudal, Cécile Caumes, Kuldip Khakh, Charles Cohen

Biomed Pharmacother· September 2023

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Serum Proteomic Analysis of Peripartum Cardiomyopathy Reveals Distinctive Dysregulation of Inflammatory and Cholesterol Metabolism Pathways.
Jana P Lovell, Kevin Bermea, Jinsheng Yu, Sylvie Rousseau, Charles D Cohen

JACC Heart Fail· September 2023

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Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.
Alison Cutts, Sultan Chowdhury, Laszlo G Ratkay, Maryanne Eyers, Clint Young, Charles J Cohen

J Pharmacol Exp Ther· July 2023

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Myocardial Immune Cells: The Basis of Cardiac Immunology.
Charles D Cohen, Sylvie T Rousseau, Kevin C Bermea, Aashik Bhalodia, Jana P Lovell

J Immunol· May 2023

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NBI-921352, a first-in-class, Na1.6 selective, sodium channel inhibitor that prevents seizures in gain-of-function mice, and wild-type mice and rats.
J P Johnson, Thilo Focken, Kuldip Khakh, Parisa Karimi Tari, Celine Dube, Charles J Cohen

Elife· March 2022

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A protocol for rapid and parallel isolation of myocytes and non-myocytes from multiple mouse hearts.
Gabriella E Farrugia, Micheal A McLellan, Kate L Weeks, Aya Matsumoto, Charles D Cohen

STAR Protoc· December 2021

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Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human Na1.7/Na1.6 Selectivity Ratios.
Ludivine Lopez, Jérôme Montnach, Barbara Oliveira-Mendes, Kuldip Khakh, Baptiste Thomas, Charles Cohen

Front Cell Dev Biol· December 2021

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Corrigendum: Characterising an Alternative Murine Model of Diabetic Cardiomyopathy.
Mitchel Tate, Darnel Prakoso, Andrew M Willis, Cheng Peng, Minh Deo, Charles D Cohen

Front Physiol· August 2021

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Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition.
Charles D Cohen, Miles J De Blasio, Man K S Lee, Gabriella E Farrugia, Darnel Prakoso

Cardiovasc Diabetol· June 2021

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