Publications by authors named "Charles D Imbusch"

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DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts.
Niklas Beumer, Charles D Imbusch, Tamara Kaufmann, Lisa Schmidleithner, Kathrin Gütter

Nat Immunol· August 2025

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Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation.
Hans Felix Staehle, Christoph Koellerer, Anne Marie Staehle, Jana Schulze, Philipp Eble, Charles D Imbusch

Cell Death Dis· August 2025

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Identifying similar populations across independent single cell studies without data integration.
Oscar González-Velasco, Malte Simon, Rüstem Yilmaz, Rosanna Parlato, Jochen Weishaupt, Charles D Imbusch

NAR Genom Bioinform· June 2025

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Bemcentinib as monotherapy and in combination with low-dose cytarabine in acute myeloid leukemia patients unfit for intensive chemotherapy: a phase 1b/2a trial.
Sonja Loges, Michael Heuser, Jörg Chromik, Grerk Sutamtewagul, Silke Kapp-Schwoerer, Charles D Imbusch

Nat Commun· March 2025

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SOX10 mediates glioblastoma cell-state plasticity.
Ka-Hou Man, Yonghe Wu, Zhenjiang Gao, Anna-Sophie Spreng, Johanna Keding, Charles D Imbusch

EMBO Rep· November 2024

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Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy.
Raphael Lutz, Florian Grünschläger, Malte Simon, Mohamed H S Awwad, Marcus Bauer, Charles D Imbusch

Nat Commun· November 2024

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Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells.
Malte Simon, Philipp Stüve, Lisa Schmidleithner, Sebastian Bittner, Niklas Beumer, Charles D Imbusch

Immunity· August 2024

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Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells.
Lisa-Marie Rieckmann, Michael Spohn, Lisa Ruff, David Agorku, Lisa Becker, Charles D Imbusch

Mol Cancer· May 2024

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The effector program of human CD8 T cells supports tissue remodeling.
Michael Delacher, Lisa Schmidleithner, Malte Simon, Philipp Stüve, Lieke Sanderink, Charles D Imbusch

J Exp Med· February 2024

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Chronic chromosome instability induced by Plk1 results in immune suppression in breast cancer.
Sridhar Kandala, Maria Ramos, Lena Voith von Voithenberg, Alberto Diaz-Jimenez, Sara Chocarro, Charles D Imbusch

Cell Rep· December 2023

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Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer.
Suhail Yousuf, Mengjie Qiu, Lena Voith von Voithenberg, Johannes Hulkkonen, Igor Macinkovic, Charles D Imbusch

Gastroenterology· October 2023

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High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD.
Uwe Schwartz, Maria Llamazares Prada, Stephanie T Pohl, Mandy Richter, Raluca Tamas, Charles D Imbusch

EMBO J· June 2023

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Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8 T cells.
Dania Riegel, Elena Romero-Fernández, Malte Simon, Akinbami Raphael Adenugba, Katrin Singer, Charles D Imbusch

Mol Cell· February 2023

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Correction to: Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.
Malte Simon, Sadaf S Mughal, Peter Horak, Sebastian Uhrig, Jonas Buchloh, Charles D Imbusch

J Transl Med· April 2022

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Pathologic responses in oligometastatic NSCLC patients treated with neoadjuvant immune checkpoint blockade with and without chemotherapy followed by surgery.
Tobias Boch, Nikolaj Frost, Linna Sommer, Tobias R Overbeck, Christoph T Michaeli, Charles D Imbusch

Lung Cancer· February 2022

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Lorlatinib Induces Durable Disease Stabilization in a Pancreatic Cancer Patient with a ROS1 p.L1950F Mutation: Case Report.
Janna-Lisa Velthaus, Peter Iglauer, Ronald Simon, Carsten Bokemeyer, Peter Bannas, Charles D Imbusch

Oncol Res Treat· October 2021

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AXL Inhibition Represents a Novel Therapeutic Approach in Negative Myeloproliferative Neoplasms.
Antonia Beitzen-Heineke, Nikolaus Berenbrok, Jonas Waizenegger, Sarina Paesler, Victoria Gensch, Charles D Imbusch

Hemasphere· September 2021

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Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.
Malte Simon, Sadaf S Mughal, Peter Horak, Sebastian Uhrig, Jonas Buchloh, Charles D Imbusch

J Transl Med· May 2021

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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells.
Michael Delacher, Malte Simon, Lieke Sanderink, Agnes Hotz-Wagenblatt, Marina Wuttke, Charles D Imbusch

Immunity· April 2021

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Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.
Elisa Espinet, Zuguang Gu, Charles D Imbusch, Nathalia A Giese, Magdalena Büscher

Cancer Discov· March 2021

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Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells.
Michael Delacher, Melanie M Barra, Yonatan Herzig, Katrin Eichelbaum, Mahmoud-Reza Rafiee, Charles D Imbusch

iScience· May 2020

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Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF.
Michael Delacher, Charles D Imbusch, Agnes Hotz-Wagenblatt, Jan-Philipp Mallm, Katharina Bauer

Immunity· February 2020

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Generation of Whole Genome Bisulfite Sequencing Libraries from Very Low DNA Input.
Dieter Weichenhan, Charles D Imbusch, Qi Wang, Benedikt Brors, Christoph Plass

Methods Mol Biol· July 2019

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Rbpj expression in regulatory T cells is critical for restraining T2 responses.
Michael Delacher, Christian Schmidl, Yonatan Herzig, Minka Breloer, Wiebke Hartmann, Charles D Imbusch

Nat Commun· April 2019

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Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters.
Fatemeh Behjati Ardakani, Kathrin Kattler, Karl Nordström, Nina Gasparoni, Gilles Gasparoni, Charles D Imbusch

Epigenetics Chromatin· November 2018

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