Publications by authors named "Charles Mein"

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Stress, epigenetic remodeling and FKBP51: Pathways to chronic pain vulnerability.
Oakley B Morgan, Samuel Singleton, Roxana Florea, Sara Hestehave, Tim Sarter, Charles A Mein

Brain Behav Immun· November 2025

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Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy.
Thomas O Millner, Pratistha Panday, Yunchen Xiao, James G Nicholson, James R Boot, Charles Mein

Brain· September 2025

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Molecular Imaging Versus Adrenal Vein Sampling for the Detection of Surgically Curable Primary Aldosteronism : A Prospective Within-Patient Trial.
Emily Goodchild, Xilin Wu, Russell Senanayake, James MacFarlane, Giulia Argentesi, Charles A Mein

Ann Intern Med· March 2025

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Engineered human myogenic cells in hydrogels generate innervated vascularized myofibers within dystrophic mouse muscle on long-term engraftment.
Anna Kowala, James Boot, Jinhong Meng, Charles A Mein, Olivier Pourquié

Cell Rep Med· March 2025

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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets.
Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein

BMC Biol· February 2025

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Transcriptomic profiling reveals a pronociceptive role for angiotensin II in inflammatory bowel disease.
James P Higham, Charity N Bhebhe, Rohit A Gupta, Michael M Tranter, Farah M Barakat, Charles A Mein

Pain· July 2024

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Multiparameter phenotyping of platelets and characterization of the effects of agonists using machine learning.
Ami Vadgama, James Boot, Nicola Dark, Harriet E Allan, Charles A Mein

Res Pract Thromb Haemost· July 2024

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Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
David T Humphreys, Amy Lewis, Belen Pan-Castillo, Giulio Berti, Charles Mein

J Cell Mol Med· May 2024

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A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.
Maria Maiarù, Richard J Acton, Eva L Woźniak, Charles A Mein, Christopher G Bell

Clin Epigenetics· September 2023

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Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
Xilin Wu, Elena A B Azizan, Emily Goodchild, Sumedha Garg, Man Hagiyama, Charles A Mein

Nat Genet· June 2023

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Deep palmar phenotyping in atopic eczema: patterns associated with filaggrin variants, disease severity and barrier function in a South Asian population.
Bjorn R Thomas, Xiang Li Tan, Stefan Van Duijvenboden, Sarah C Hogan, Aaron J Hughes, Charles A Mein

Br J Dermatol· May 2023

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ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK.
Benjamin M Jacobs, Luisa Schalk, Angie Dunne, Antonio Scalfari, Ashwini Nandoskar, Charles A Mein

BMJ Open· May 2023

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[C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial.
Xilin Wu, Russell Senanayake, Emily Goodchild, Waiel A Bashari, Jackie Salsbury, Charles A Mein

Nat Med· January 2023

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Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome.
Robin Mesnage, Simona Panzacchi, Emma Bourne, Charles A Mein, Melissa J Perry

Front Microbiol· October 2022

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Comparative Toxicogenomics of Glyphosate and Roundup Herbicides by Mammalian Stem Cell-Based Genotoxicity Assays and Molecular Profiling in Sprague-Dawley Rats.
Robin Mesnage, Mariam Ibragim, Daniele Mandrioli, Laura Falcioni, Eva Tibaldi, Charles A Mein

Toxicol Sci· February 2022

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Alterations in small RNA profiles in liver following a subchronic exposure to a low-dose pesticide mixture in Sprague-Dawley rats.
Robin Mesnage, Nadiya Mahmud, Charles A Mein, Michael N Antoniou

Toxicol Lett· December 2021

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Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause.
Junhua Zhou, Elena A B Azizan, Claudia P Cabrera, Fabio L Fernandes-Rosa, Sheerazed Boulkroun, Charles A Mein

Nat Genet· September 2021

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Neuronal let-7b-5p acts through the Hippo-YAP pathway in neonatal encephalopathy.
Vennila Ponnusamy, Richard T H Ip, Moumin A E K Mohamed, Paul Clarke, Eva Wozniak, Charles Mein

Commun Biol· September 2021

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Areca catechu-(Betel-nut)-induced whole transcriptome changes in a human monocyte cell line that may have relevance to diabetes and obesity; a pilot study.
Shirleny R Cardosa, B William Ogunkolade, Rob Lowe, Emanuel Savage, Charles A Mein

BMC Endocr Disord· August 2021

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The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation.
Richard J Acton, Wei Yuan, Fei Gao, Yudong Xia, Emma Bourne, Charles A Mein

Nat Commun· May 2021

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Multi-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in rats.
Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Mariam Ibragim, Charles A Mein

Commun Biol· April 2021

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Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin.
Marilena Crescente, Paul C Armstrong, Nicholas S Kirkby, Matthew L Edin, Melissa V Chan, Charles A Mein

FASEB J· August 2020

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Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan.
Nasira M Lone, Saba Riaz, Amna Z Eusaph, Charles A Mein, Eva L Wozniak

Sci Rep· February 2020

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Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes.
Martina Biserni, Robin Mesnage, Raquel Ferro, Eva Wozniak, Theodoros Xenakis, Charles A Mein

Toxicol Sci· August 2019

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Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages.
Alison M Thomas, Claudia P Cabrera, Malcolm Finlay, Kulvinder Lall, Muriel Nobles, Charles A Mein

Physiol Genomics· August 2019

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