Publications by authors named "Charles Patek"

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K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.
Feijun Luo, Hongtao Ye, Rifat Hamoudi, Gehong Dong, Wenyan Zhang, Charles E Patek

J Pathol· April 2010

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Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.
Feijun Luo, David G Brooks, Hongtao Ye, Rifat Hamoudi, George Poulogiannis, Charles E Patek

Int J Exp Pathol· October 2009

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Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396).
Charles E Patek, David G Brownstein, Stewart Fleming, Caroline Wroe, Lorraine Rose

Transgenic Res· June 2008

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The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.
Charles E Patek, Mark J Arends, Lorraine Rose, Feijun Luo, Marion Walker

BMC Gastroenterol· June 2008

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Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
Charles E Patek, Mark J Arends, William A H Wallace, Feijun Luo, Suzanne Hagan

Exp Cell Res· March 2008

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Stem cell gene expression changes induced specifically by mutated K-ras.
Feijun Luo, Rifat Hamoudi, David G Brooks, Charles E Patek, Mark J Arends

Gene Expr· March 2008

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The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.
Sarah J Plowman, Mark J Arends, David G Brownstein, Feijun Luo, Paul S Devenney, Charles E Patek

Exp Cell Res· January 2006

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Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors.
Saeid Amini Nik, Peter Hohenstein, Ali Jadidizadeh, Kim Van Dam, Adriana Bastidas, Charles E Patek

Int J Cancer· March 2005

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While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.
Sarah J Plowman, D James Williamson, Maureen J O'Sullivan, Jennifer Doig, Ann-Marie Ritchie, Charles E Patek

Mol Cell Biol· December 2003

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Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.
Charles E Patek, Stewart Fleming, Colin G Miles, Christopher O Bellamy, Michael Ladomery

Hum Mol Genet· September 2003

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K-ras proto-oncogene exhibits tumor suppressor activity as its absence promotes tumorigenesis in murine teratomas.
Roberta M James, Mark J Arends, Sarah J Plowman, David G Brooks, Colin G Miles, Charles E Patek

Mol Cancer Res· September 2003

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The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis.
Aswin L Menke, Annemieke IJpenberg, Stewart Fleming, Allyson Ross, Claire N Medine, Charles E Patek

J Pathol· August 2003

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Polyploid cells in the mouse ovary.
Margaret A Keighren, Leah P Macfadyen, Alan S Hill, Charles E Patek, Evelyn E Telfer

J Anat· June 2003

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Mice lacking the 68-amino-acid, mammal-specific N-terminal extension of WT1 develop normally and are fertile.
Colin G Miles, Joan Slight, Lee Spraggon, Maureen O'Sullivan, Charles Patek

Mol Cell Biol· April 2003

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Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes.
Jan Cullingworth, Martin L Hooper, David J Harrison, John O Mason, Christian Sirard, Charles E Patek

Oncogene· July 2002

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