Publications by authors named "Lee Spraggon"

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Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination.
Rahul K Suryawanshi, Taha Y Taha, Maria McCavitt-Malvido, Ines Silva, Mir M Khalid, Lee Spraggon

Emerg Microbes Infect· December 2023

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Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.
Abdullah M Syed, Alison Ciling, Taha Y Taha, Irene P Chen, Mir M Khalid, Lee Spraggon

Proc Natl Acad Sci U S A· August 2022

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Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.
Rahul K Suryawanshi, Irene P Chen, Tongcui Ma, Abdullah M Syed, Noah Brazer, Lee Spraggon

Nature· July 2022

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Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor.
Alifiani Bonita Hartono, Hong-Jun Kang, Lawrence Shi, Whitney Phipps, Nathan Ungerleider, Lee Spraggon

Oncogenesis· April 2022

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Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination.
Rahul K Suryawanshi, Irene P Chen, Tongcui Ma, Abdullah M Syed, Noah Brazer, Lee Spraggon

medRxiv· February 2022

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Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling.
Roger S Smith, Igor Odintsov, Zebing Liu, Allan Jo-Weng Lui, Takuo Hayashi, Lee Spraggon

Dis Model Mech· January 2022

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Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.
Abdullah M Syed, Alison Ciling, Mir M Khalid, Bharath Sreekumar, Pei-Yi Chen, Lee Spraggon

medRxiv· January 2022

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Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell Tumor.
Koichi Ogura, Romel Somwar, Julija Hmeljak, Heather Magnan, Ryma Benayed, Lee Spraggon

Clin Cancer Res· February 2021

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Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel Fusion-Driven Cancer.
Emily K Slotkin, Daniel Diolaiti, Neerav N Shukla, Filemon S Dela Cruz, Jennifer J Clark, Lee Spraggon

Cancer Discov· May 2019

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amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
Pang-Dian Fan, Giuseppe Narzisi, Anitha D Jayaprakash, Elisa Venturini, Nicolas Robine, Lee Spraggon

Proc Natl Acad Sci U S A· June 2018

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Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.
Lee Spraggon, Luciano G Martelotto, Julija Hmeljak, Tyler D Hitchman, Jiang Wang

J Pathol· May 2017

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Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples.
Luciano G Martelotto, Timour Baslan, Jude Kendall, Felipe C Geyer, Kathleen A Burke, Lee Spraggon

Nat Med· March 2017

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In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA.
Gaspare La Rocca, Scott H Olejniczak, Alvaro J González, Daniel Briskin, Joana A Vidigal, Lee Spraggon

Proc Natl Acad Sci U S A· January 2015

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Stromal protein Ecm1 regulates ureteric bud patterning and branching.
Suneeta S Paroly, Fengwei Wang, Lee Spraggon, Joseph Merregaert, Ekatherina Batourina

PLoS One· September 2014

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U1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer.
Lee Spraggon, Luca Cartegni

Int J Cell Biol· November 2013

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Antisense Modulation of RNA Processing as a Therapeutic Approach in Cancer Therapy.
Lee Spraggon, Luca Cartegni

Drug Discov Today Ther Strateg· January 2013

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Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC.
Virginia Castilla-Llorente, Lee Spraggon, Miwako Okamura, Saif Naseeruddin, Matthew Adamow

J Cell Biol· August 2012

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A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression.
Abdelkader Essafi, Anna Webb, Rachel L Berry, Joan Slight, Sally F Burn, Lee Spraggon

Dev Cell· September 2011

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Non-cell-autonomous retinoid signaling is crucial for renal development.
Carolina Rosselot, Lee Spraggon, Ian Chia, Ekatherina Batourina, Paul Riccio

Development· January 2010

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Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.
Jamie A Davies, Michael Ladomery, Peter Hohenstein, Lydia Michael, Anna Shafe, Lee Spraggon

Hum Mol Genet· January 2004

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Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.
Charles E Patek, Stewart Fleming, Colin G Miles, Christopher O Bellamy, Michael Ladomery, Lee Spraggon

Hum Mol Genet· September 2003

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The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis.
Aswin L Menke, Annemieke IJpenberg, Stewart Fleming, Allyson Ross, Claire N Medine, Lee Spraggon

J Pathol· August 2003

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Mice lacking the 68-amino-acid, mammal-specific N-terminal extension of WT1 develop normally and are fertile.
Colin G Miles, Joan Slight, Lee Spraggon, Maureen O'Sullivan, Charles Patek

Mol Cell Biol· April 2003

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Genetic interactions between the Wilms' tumor 1 gene and the p53 gene.
Aswin L Menke, Alan R Clarke, Andrea Leitch, Annemieke Ijpenberg, Kathy A Williamson, Lee Spraggon

Cancer Res· November 2002

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