Publications by authors named "Charles Rundle"

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Assessment of Feasibility of the M2 Macrophage-Based Adoptive Gene Transfer Strategy for Osteoarthritis with a Mouse Model.
Matilda H-C Sheng, David J Baylink, Charles H Rundle, Kin-Hing William Lau

Cells· July 2025

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Overexpression of miR17 ~ 92 in Myeloid Cells in Mice Increased Bone Mass Through Reduced Bone Resorption and Increased Bone Formation in Sex-Dependent Manner.
Matilda H-C Sheng, Virginia M Stiffel, Jordan Taipia, Charles H Rundle, Kin-Hing William Lau

Calcif Tissue Int· January 2025

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Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner.
Matilda H-C Sheng, Charles H Rundle, David J Baylink, Kin-Hing William Lau

Calcif Tissue Int· January 2025

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Microvesicles Released by Osteoclastic Cells Exhibited Chondrogenic, Osteogenic, and Anti-Inflammatory Activities: An Evaluation of the Feasibility of Their Use for Treatment of Osteoarthritis in a Mouse Model.
Matilda H-C Sheng, Charles H Rundle, Kin-Hing William Lau

Cells· January 2025

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Sequential application of small molecule therapy enhances chondrogenesis and angiogenesis in murine segmental defect bone repair.
Charles H Rundle, Gustavo A Gomez, Sheila Pourteymoor, Subburaman Mohan

J Orthop Res· July 2023

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Defective bone repletion in aged Balb/cBy mice was caused by impaired osteoblastic differentiation.
Matilda H-C Sheng, Kin-Hing William Lau, Charles H Rundle, Anar Alsunna, Sean M Wilson

J Bone Miner Metab· November 2022

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Contrasting effects of , an obesity gene, on trabecular bone volume and bone marrow adiposity.
Gustavo A Gomez, Charles H Rundle, Weirong Xing, Chandrasekhar Kesavan, Sheila Pourteymoor

Elife· November 2022

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A Novel EphA4 Signaling-Based Therapeutic Strategy for Osteoarthritis in Mice.
Virginia M Stiffel, Charles H Rundle, Matilda H-C Sheng, Subhashri Das, Kin-Hing William Lau

J Bone Miner Res· April 2022

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Repeated mild traumatic brain injury impairs fracture healing in male mice.
Chandrasekhar Kesavan, Charles Rundle, Subburaman Mohan

BMC Res Notes· January 2022

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The EphA4 Signaling is Anti-catabolic in Synoviocytes but Pro-anabolic in Articular Chondrocytes.
Virginia M Stiffel, Alexander Thomas, Charles H Rundle, Matilda H-C Sheng, Kin-Hing William Lau

Calcif Tissue Int· December 2020

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Unique anabolic action of stem cell gene therapy overexpressing PDGFB-DSS6 fusion protein in OVX osteoporosis mouse model.
Wanqiu Chen, Samiksha Wasnik, Yawen Fu, Leslie Aranda, Charles H Rundle

Bone Rep· June 2020

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A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing.
Amandeep Kaur, Subburaman Mohan, Charles H Rundle

Animal Model Exp Med· June 2020

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A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis.
Virginia Stiffel, Charles H Rundle, Matilda H-C Sheng, Subhashri Das, Kin-Hing William Lau

Calcif Tissue Int· February 2020

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Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90 skeletal stem cells in fracture sites.
Samiksha Wasnik, Ram Lakhan, David J Baylink, Charles H Rundle, Yi Xu

Sci Adv· July 2019

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Changes in ephrin gene expression during bone healing identify a restricted repertoire of ephrins mediating fracture repair.
Amandeep Kaur, Weirong Xing, Subburaman Mohan, Charles H Rundle

Histochem Cell Biol· January 2019

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1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
Samiksha Wasnik, Charles H Rundle, David J Baylink, Mohammad Safaie Yazdi, Edmundo E Carreon

JCI Insight· September 2018

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Role of IGF1 and EFN-EPH signaling in skeletal metabolism.
Richard C Lindsey, Charles H Rundle, Subburaman Mohan

J Mol Endocrinol· July 2018

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Conditional Disruption of in Osteoclasts Led to Activation of Osteoclasts and Loss of Trabecular Bone In Part Through Suppression of the miR17-Mediated Downregulation of Protein-Tyrosine Phosphatase-oc in Mice.
Kin-Hing William Lau, Virginia M Stiffel, Charles H Rundle, Mehran Amoui, Jordan Tapia

JBMR Plus· October 2017

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Unique Regenerative Mechanism to Replace Bone Lost During Dietary Bone Depletion in Weanling Mice.
Matilda H-C Sheng, Kin-Hing William Lau, Ram Lakhan, Abu Shufian Ishtiaq Ahmed, Charles H Rundle

Endocrinology· April 2017

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Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice.
Kin-Hing W Lau, Charles H Rundle, Xiao-Dong Zhou, David J Baylink, Matilda H-C Sheng

Bone· November 2016

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Bidirectional ephrin signaling in bone.
Charles H Rundle, Weirong Xing, Kin-Hing William Lau, Subburaman Mohan

Osteoporos Sarcopenia· June 2016

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Reduced bone mass accrual in mouse model of repetitive mild traumatic brain injury.
Hongrun Yu, Jon E Wergedal, Charles H Rundle, Subburaman Mohan

J Rehabil Res Dev· November 2015

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PDGFB-based stem cell gene therapy increases bone strength in the mouse.
Wanqiu Chen, David J Baylink, Justin Brier-Jones, Amanda Neises, Jason B Kiroyan, Charles H Rundle

Proc Natl Acad Sci U S A· July 2015

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Direct lentiviral-cyclooxygenase 2 application to the tendon-bone interface promotes osteointegration and enhances return of the pull-out tensile strength of the tendon graft in a rat model of biceps tenodesis.
Charles H Rundle, Shin-Tai Chen, Michael J Coen, Jon E Wergedal, Virginia Stiffel

PLoS One· January 2015

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Microarray Analysis of Gene Expression Reveals that Cyclo-oxygenase-2 Gene Therapy Up-regulates Hematopoiesis and Down-regulates Inflammation During Endochondral Bone Fracture Healing.
K-H William Lau, Nicoleta L Popa, Charles H Rundle

J Bone Metab· August 2014

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