Publications by authors named "Charlotte Edling"

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Transcriptomic Remodeling of Pulmonary Vein Sleeves Suggests a Role in Atrial Arrhythmogenesis in Thoroughbred Horses.
Magdalena Arevalo-Turrubiarte, Charlotte E Edling, Carla Moller-Levet, Bronte Forbes, Victoria Kemp

Ann N Y Acad Sci· December 2025

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In situ exogenous alpha-synuclein aggregates inhibit murine ventricular voltage-gated inward sodium and outward potassium currents.
Bonn Lee, Shiraz Ahmad, Charlotte E Edling, Hugh R Matthews, Christopher L-H Huang

J Parkinsons Dis· November 2025

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Intact microdissection of stellate ganglia in a Parkinson's disease model reveals aggregation of mutant human α-synuclein in their cell bodies.
Bonn Lee, Shiraz Ahmad, Charlotte E Edling, Fiona E N LeBeau, Kamalan Jeevaratnam

Exp Physiol· June 2025

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Gene expression patterns of the four cardiac chambers in the Thoroughbred horse.
Charlotte E Edling, Magdalena Arevalo-Turrubiarte, Antoine Premont, Marcos Castellanos Uribe, Bronte Forbes

J Equine Vet Sci· June 2025

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Mass spectrometry reveals age-dependent collagen decline in murine atria.
Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre-Barreiro, Kamalan Jeevaratnam

Ann N Y Acad Sci· June 2025

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Age-dependent reduction in voltage-gated inward sodium current and Scn8a gene expression in murine stellate ganglia.
Bonn Lee, Shiraz Ahmad, Charlotte E Edling, Christopher L-H Huang, Fiona E N LeBeau

Ann N Y Acad Sci· March 2025

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Clinical and Non-Clinical Cardiovascular Disease Associated Pathologies in Parkinson's Disease.
Bonn Lee, Charlotte Edling, Shiraz Ahmad, Fiona E N LeBeau, Gary Tse

Int J Mol Sci· August 2023

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Framing Heartaches: The Cardiac ECM and the Effects of Age.
Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Kamalan Jeevaratnam

Int J Mol Sci· March 2023

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Anti-malarial drugs: Mechanisms underlying their proarrhythmic effects.
Khalil Saadeh, Nakulan Nantha Kumar, Ibrahim Talal Fazmin, Charlotte E Edling, Kamalan Jeevaratnam

Br J Pharmacol· December 2022

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Cardiac ion channel expression in the equine model - In-silico prediction utilising RNA sequencing data from mixed tissue samples.
Antoine Premont, Khalil Saadeh, Charlotte Edling, Rebecca Lewis, Celia M Marr

Physiol Rep· July 2022

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Transcriptional profiles of genes related to electrophysiological function in Scn5a murine hearts.
Michael Takla, Charlotte E Edling, Kevin Zhang, Khalil Saadeh, Gary Tse

Physiol Rep· October 2021

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Molecular basis of ventricular arrhythmogenicity in a Pgc-1α deficient murine model.
Khalil Saadeh, Karan R Chadda, Shiraz Ahmad, Haseeb Valli, Nakulan Nanthakumar, Charlotte E Edling

Mol Genet Metab Rep· June 2021

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Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.
Khalil Saadeh, Zakaria Achercouk, Ibrahim T Fazmin, Nakulan Nantha Kumar, Samantha C Salvage, Charlotte E Edling

Ann N Y Acad Sci· October 2020

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Circulating microRNA as a Biomarker for Coronary Artery Disease.
Ibrahim T Fazmin, Zakaria Achercouk, Charlotte E Edling, Asri Said, Kamalan Jeevaratnam

Biomolecules· September 2020

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Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction.
Charlotte E Edling, Ibrahim T Fazmin, Khalil Saadeh, Karan R Chadda, Shiraz Ahmad

Biosci Rep· December 2019

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Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer.
Aikaterini Emmanouilidi, Chanse A Fyffe, Riccardo Ferro, Charlotte E Edling, Emily Capone

J Exp Clin Cancer Res· May 2019

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Ageing in mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology.
Charlotte E Edling, Ibrahim T Fazmin, Karan R Chadda, Shiraz Ahmad, Haseeb Valli

Biosci Rep· April 2019

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Atrial Transcriptional Profiles of Molecular Targets Mediating Electrophysiological Function in Aging and β Deficient Murine Hearts.
Charlotte E Edling, Ibrahim T Fazmin, Karan R Chadda, Shiraz Ahmad, Haseeb Valli

Front Physiol· April 2019

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Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Deficient Murine Atria.
Karan R Chadda, Charlotte E Edling, Haseeb Valli, Shiraz Ahmad, Christopher L-H Huang

Int J Mol Sci· November 2018

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Arrhythmogenic mechanisms of obstructive sleep apnea in heart failure patients.
Karan R Chadda, Ibrahim T Fazmin, Shiraz Ahmad, Haseeb Valli, Charlotte E Edling

Sleep· September 2018

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Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β hearts.
Shiraz Ahmad, Haseeb Valli, Charlotte E Edling, Andrew A Grace, Kamalan Jeevaratnam

Pflugers Arch· December 2017

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Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.
Claire L Ryall, Katrina Viloria, Fadel Lhaf, Anthony J Walker, Aileen King, Charlotte Edling

J Biol Chem· October 2014

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Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.
Charlotte E Edling, Federico Selvaggi, Ragheda Ghonaim, Tania Maffucci, Marco Falasca

Cancer Biol Ther· May 2014

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PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma.
Francesco Dituri, Antonio Mazzocca, Luigi Lupo, Charlotte E Edling, Amalia Azzariti

Int J Cancer· June 2012

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Targeting phosphoinositide 3-kinase pathways in pancreatic cancer--from molecular signalling to clinical trials.
Marco Falasca, Federico Selvaggi, Richard Buus, Sara Sulpizio, Charlotte E Edling

Anticancer Agents Med Chem· June 2011

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