Publications by authors named "Cheng-Yu Fang"

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Enhancing cognitive memory function using polysaccharides modulating autophagy and reshaping the gut microbiota.
Jia-De Chen, Sheng-Yi Chen, Chia-Chien Liao, Cheng-Yu Fang, Gow-Chin Yen

Food Funct· October 2025

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Fagopyrum esculentum polysaccharides mitigate obesity by reshaping gut microbiota and enhancing lipid metabolism in high-fat diet-fed mice.
Cheng-Yu Fang, Sheng-Yi Chen, Chia-Chien Liao, Jia-De Chen, Gow-Chin Yen

Int J Biol Macromol· September 2025

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Natural and artificial siderophores: Iron-based applications and beyond.
Zih-Jheng Lin, Cheng-Yu Fang, Tsung-Shing Andrew Wang

Curr Opin Chem Biol· August 2025

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Comparison of multiple linear regression and machine learning methods in predicting cognitive function in older Chinese type 2 diabetes patients.
Chi-Hao Liu, Chung-Hsin Peng, Li-Ying Huang, Fang-Yu Chen, Chun-Heng Kuo, Yu-Fang Cheng

BMC Neurol· January 2024

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Photoreceptor changes in Leber hereditary optic neuropathy with m.G11778A mutation.
Qing-Mei Miao, Yu-Fang Cheng, Hong-Mei Zheng, Jia-Jia Yuan, Chang-Zheng Chen

Int J Ophthalmol· June 2023

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Comparing Multiple Linear Regression and Machine Learning in Predicting Diabetic Urine Albumin-Creatinine Ratio in a 4-Year Follow-Up Study.
Li-Ying Huang, Fang-Yu Chen, Mao-Jhen Jhou, Chun-Heng Kuo, Chung-Ze Wu, Yu-Fang Cheng

J Clin Med· June 2022

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Night shift work and the risk of metabolic syndrome: Findings from an 8-year hospital cohort.
Wan-Ju Cheng, Chiu-Shong Liu, Kai-Chieh Hu, Yu-Fang Cheng, Kati Karhula

PLoS One· January 2022

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Association Between Emotional Disorders and Speech and Language Impairments: A National Population-Based Study.
Yi-Chen Lee, Vincent Chin-Hung Chen, Yao-Hsu Yang, Ting-Yu Kuo, Tai-Hsin Hung, Yu-Fang Cheng

Child Psychiatry Hum Dev· June 2020

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Risk of schizophrenia among people with obsessive-compulsive disorder: A nationwide population-based cohort study.
Yu-Fang Cheng, Vincent Chin-Hung Chen, Yao-Hsu Yang, Ko-Jung Chen, Yi-Chen Lee

Schizophr Res· July 2019

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Strong association between metabolically-abnormal obesity and gallstone disease in adults under 50 years.
Pei-Yuan Su, Yu-Chun Hsu, Yu-Fang Cheng, Chew-Teng Kor, Wei-Wen Su

BMC Gastroenterol· July 2019

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Correction to Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.
Zhong-Zhen Zhou, Yu-Fang Cheng, Zheng-Qiang Zou, Bing-Chen Ge, Hui Yu

ACS Chem Neurosci· July 2018

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Design, synthesis and biological evaluation of substituted aminopyridazin-3(2H)-ones as G0/G1-phase arresting agents with apoptosis-inducing activities.
Bing-Chen Ge, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Bao-Ming Xi

Eur J Med Chem· December 2017

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Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.
Zhong-Zhen Zhou, Xiu-Dong Shi, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang

Eur J Med Chem· September 2017

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Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-B Inhibition.
Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang

J Pharmacol Exp Ther· July 2017

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Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.
Zhong-Zhen Zhou, Yu-Fang Cheng, Zheng-Qiang Zou, Bing-Chen Ge, Hui Yu

ACS Chem Neurosci· January 2017

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Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings.
Zhong-Zhen Zhou, Bing-Chen Ge, Qiu-Ping Zhong, Chang Huang, Yu-Fang Cheng

Eur J Med Chem· November 2016

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Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer.
Xiao-Feng Wang, Xiao-Wei Zhang, Rui-Xi Hua, Yi-Qun Du, Ming-Zhu Huang, Yu Fang Cheng

Oncotarget· September 2016

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Involvement of norepinephrine and serotonin system in antidepressant-like effects of hederagenin in the rat model of unpredictable chronic mild stress-induced depression.
Bao-Fang Liang, Fang Huang, Hai-Tao Wang, Guo-Hua Wang, Xin Yuan, Yu-Fang Cheng

Pharm Biol· March 2015

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Chlorbipram: a novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer.
Ming-Zi Zhang, Zhong-Zhen Zhou, Xin Yuan, Yu-Fang Cheng, Bing-Tian Bi, Mei-Fang Gong

Eur J Pharmacol· December 2013

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Neurorehabilitation of congenital mirror movements enhanced by stroke: a case report with fMRI study.
Yi-Ching Huang, Kai-Hua Chen, Mei-Yu Yeh, Yuan-Hsiung Tsai, Yu-Fang Cheng

Clin Neurol Neurosurg· October 2013

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The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.
Chuang Wang, Xue-Mei Yang, Ye-Ye Zhuo, Heng Zhou, Huan-Bing Lin, Yu-Fang Cheng

Int J Neuropsychopharmacol· July 2012

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Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease.
Bing-Tian Bi, Huan-Bing Lin, Yu-Fang Cheng, Heng Zhou, Ting Lin

Neurochem Int· February 2012

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Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats.
Ling-Xia Li, Yu-Fang Cheng, Huan-Bing Lin, Chuang Wang, Jiang-Ping Xu

Metab Brain Dis· March 2011

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Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling.
Yun-Feng Li, Yu-Fang Cheng, Ying Huang, Marco Conti, Steven P Wilson

J Neurosci· January 2011

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Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats.
Yu-Fang Cheng, Chuang Wang, Huan-Bing Lin, Yun-Feng Li, Ying Huang

Psychopharmacology (Berl)· October 2010

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