Publications by authors named "Chengyu Prince"

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Systemic T-cell activation and IFN-γ activity in indeterminate severe hepatitis are reminiscent of hemophagocytic lymphohistiocytosis: Implications for T-cell- and IFN-γ-directed therapies.
Thinh H Nguyen, Prakash Satwani, Deepak Kumar, Urvi Kapoor, Sakshi Malik, Chengyu Prince

J Allergy Clin Immunol· January 2025

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Frequency of HLA-DRCD38 T cells identifies and quantifies T-cell activation in hemophagocytic lymphohistiocytosis, hyperinflammation, and immune regulatory disorders.
Thinh H Nguyen, Deepak Kumar, Chengyu Prince, Dylan Martini, Jocelyn R Grunwell

J Allergy Clin Immunol· January 2024

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Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis.
Jenny Shim, Sunita Park, Suresh Venkateswaran, Deepak Kumar, Chengyu Prince

Blood· December 2023

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mTOR inhibition attenuates cTfh cell dysregulation and chronic T-cell activation in multilineage immune cytopenias.
Deepak Kumar, Thinh H Nguyen, Carolyn M Bennett, Chengyu Prince, Laura Lucas

Blood· January 2023

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HSCT using carrier donors for CD40L deficiency results in excellent immune function and higher CD40L expression in cTfh.
Shanmuganathan Chandrakasan, Sharat Chandra, Chengyu Prince, Lisa J Kobrynski, Laura Lucas

Blood Adv· June 2022

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Thrombopoietin-based CAR-T cells demonstrate in vitro and in vivo cytotoxicity to MPL positive acute myelogenous leukemia and hematopoietic stem cells.
Jaquelyn T Zoine, Chengyu Prince, Jamie Y Story, Gianna M Branella, Allison M Lytle

Gene Ther· May 2022

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Distinguishing immune activation and inflammatory signatures of multisystem inflammatory syndrome in children (MIS-C) versus hemophagocytic lymphohistiocytosis (HLH).
Deepak Kumar, Christina A Rostad, Preeti Jaggi, D Sofia Villacis Nunez, Chengyu Prince

J Allergy Clin Immunol· May 2022

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T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome.
Deepak Kumar, Chengyu Prince, Carolyn M Bennett, Michael Briones, Laura Lucas

Blood· January 2022

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Non-genotoxic conditioning facilitates hematopoietic stem cell gene therapy for hemophilia A using bioengineered factor VIII.
Athena L Russell, Chengyu Prince, Taran S Lundgren, Kristopher A Knight, Gabriela Denning

Mol Ther Methods Clin Dev· June 2021

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Lentiviral Gene Therapy for Familial Hemophagocytic Lymphohistiocytosis Type 3, Caused by Genetic Defects.
Sarah E Takushi, Na Yoon Paik, Andrew Fedanov, Chengyu Prince, Christopher B Doering

Hum Gene Ther· June 2020

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Hypogammaglobulinemia with decreased class-switched B-cells and dysregulated T-follicular-helper cells in IPEX syndrome.
Oded Shamriz, Kiran Patel, Rebecca A Marsh, Jacob Bleesing, Avni Y Joshi, Chengyu Prince

Clin Immunol· December 2018

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Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.
Guiying Cui, Kazi S Rahman, Daniel T Infield, Christopher Kuang, Chengyu Z Prince

J Gen Physiol· August 2014

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Two salt bridges differentially contribute to the maintenance of cystic fibrosis transmembrane conductance regulator (CFTR) channel function.
Guiying Cui, Cody S Freeman, Taylor Knotts, Chengyu Z Prince, Christopher Kuang

J Biol Chem· July 2013

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The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention.
Susan K Peirce, Harry W Findley, Chengyu Prince, Anindya Dasgupta, Todd Cooper

Cancer Chemother Pharmacol· August 2011

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HRT1 modulates vascular smooth muscle cell proliferation and apoptosis.
Wenli Wang, Chengyu Z Prince, Xing Hu, Matthew J Pollman

Biochem Biophys Res Commun· August 2003

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Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation. Resistance to Fas ligand-induced apoptosis.
Wenli Wang, Chengyu Z Prince, Yongshan Mou, Matthew J Pollman

J Biol Chem· June 2002

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Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK.
Wenli Wang, Alexandre H Campos, Chengyu Z Prince, Yongshan Mou, Matthew J Pollman

J Biol Chem· June 2002

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