Publications by authors named "Chester A Mathis"

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First-in-human PET neuroimaging of [F]OXD-2314.
Emily Murrell, Lucas Narciso, Kimberly L Desmond, Caitlin Chow, Anton Lindberg, Chester A Mathis

Eur J Nucl Med Mol Imaging· December 2025

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An inverse association of cerebral amyloid-β deposition and serum docosahexaenoic acid levels in cognitively normal older adults in Japan.
Akira Sekikawa, Aya Higashiyama, Brian J Lopresti, Masafumi Ihara, Chendi Cui, Chester A Mathis

J Alzheimers Dis· July 2025

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Discovery of -(6-Methoxypyridin-3-yl)quinoline-2-amine Derivatives for Imaging Aggregated α-Synuclein in Parkinson's Disease with Positron Emission Tomography.
Haiyang Zhao, Tianyu Huang, Dhruva D Dhavale, Jennifer Y O'Shea, Zsofia Lengyel-Zhand, Chester A Mathis

Cells· July 2025

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The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease.
Gui-Long Tian, Chia-Ju Hsieh, Dinahlee Saturnino Guarino, Thomas J A Graham, Zsofia Lengyel-Zhand, Chester A Mathis

RSC Med Chem· June 2025

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Radiosynthesis, Characterization, and PET Neuroimaging of [F]F-4 for Tau Protein: A First-in-Human PET Study.
Anton Lindberg, Junchao Tong, Chao Zheng, Andre Mueller, Heiko Kroth, Chester A Mathis

ACS Chem Neurosci· March 2025

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Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1-indoles as Tauopathy Positron Emission Tomography Radiotracers.
Jeffrey S Stehouwer, Guofeng Huang, Dinahlee Saturnino Guarino, Manik L Debnath, Ashok Polu, Chester A Mathis

J Med Chem· March 2025

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F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy.
Michael L Alosco, Jhony Mejía Pérez, Julia E Culhane, Ranjani Shankar, Christopher J Nowinski, Chester A Mathis

Mol Neurodegener· February 2025

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Kinetic modeling of the monoamine oxidase-B radioligand [F]SMBT-1 in human brain with positron emission tomography.
Brian J Lopresti, Jeffrey Stehouwer, Alexandria C Reese, Neale S Mason, Sarah K Royse, Chester A Mathis

J Cereb Blood Flow Metab· November 2024

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Implementation and Assessment of Tau Thresholds in Non-Demented Individuals as Predictors of Cognitive Decline in Tau Imaging Studies.
Alexandra Gogola, Ann D Cohen, Beth Snitz, Davneet Minhas, Dana Tudorascu, Chester A Mathis

J Alzheimers Dis· August 2024

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Ligand-based design of [F]OXD-2314 for PET imaging in non-Alzheimer's disease tauopathies.
Anton Lindberg, Emily Murrell, Junchao Tong, N Scott Mason, Daniel Sohn, Chester A Mathis

Nat Commun· June 2024

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Development of Pyridothiophene Compounds for PET Imaging of α-Synuclein.
Anna Pees, Junchao Tong, Saritha Birudaraju, Yogeshkumar S Munot, Steven H Liang, Chester A Mathis

Chemistry· April 2024

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In vitro evaluation of [H]PI-2620 and structural derivatives in non-Alzheimer's tauopathies.
Cassis Varlow, Chester A Mathis, Neil Vasdev

Nucl Med Biol· March 2024

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Characterizing the emergence of amyloid and tau burden in Down syndrome.
Matthew D Zammit, Tobey J Betthauser, Andrew K McVea, Charles M Laymon, Dana L Tudorascu, Chester A Mathis

Alzheimers Dement· January 2024

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Association Between β-Amyloid Accumulation and Incident Dementia in Individuals 80 Years or Older Without Dementia.
Oscar L Lopez, Victor L Villemagne, Yue-Fang Chang, Ann D Cohen, William E Klunk, Chester A Mathis

Neurology· January 2024

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Biostatistical Estimation of Tau Threshold Hallmarks (BETTH) Algorithm for Human Tau PET Imaging Studies.
Alexandra Gogola, Brian J Lopresti, Dana Tudorascu, Beth Snitz, Davneet Minhas, Chester A Mathis

J Nucl Med· November 2023

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A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Ho Young Kim, Wai Kit Chia, Chia-Ju Hsieh, Dinahlee Saturnino Guarino, Thomas J A Graham, Chester A Mathis

J Med Chem· September 2023

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Low thalamic activity during a digit-symbol substitution task is associated with symptoms of subjective cognitive decline.
Akiko Mizuno, Helmet Talib Karim, Maria J Ly, Brian J Lopresti, Ann D Cohen, Chester A Mathis

Front Psychiatry· September 2023

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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.
Bieneke Janssen, Guilong Tian, Zsofia Lengyel-Zhand, Chia-Ju Hsieh, Marshall G Lougee, Chester A Mathis

Mol Imaging Biol· August 2023

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Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers.
Thomas J A Graham, Anton Lindberg, Junchao Tong, Jeffrey S Stehouwer, Neil Vasdev, Chester A Mathis

J Med Chem· August 2023

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Beyond monoamines: I. Novel targets and radiotracers for Positron emission tomography imaging in psychiatric disorders.
Brian J Lopresti, Sarah K Royse, Chester A Mathis, Savannah A Tollefson, Rajesh Narendran

J Neurochem· February 2023

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Beyond monoamines: II. Novel applications for PET imaging in psychiatric disorders.
Sarah K Royse, Brian J Lopresti, Chester A Mathis, Savannah Tollefson, Rajesh Narendran

J Neurochem· February 2023

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In Pre-Clinical AD Small Vessel Disease is Associated With Altered Hippocampal Connectivity and Atrophy.
Minjie Wu, Noah Schweitzer, Bistra E Iordanova, Edythe Halligan-Eddy, Dana L Tudorascu, Chester A Mathis

Am J Geriatr Psychiatry· February 2023

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Low untreated systolic blood pressure over 18 years is associated with survival free of dementia age 90.
Lewis H Kuller, Beth E Snitz, Timothy M Hughes, Yuefang Chang, Ann D Cohen, Chester A Mathis

Alzheimers Dement· November 2022

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Prefrontal and Striatal Dopamine Release Are Inversely Correlated in Schizophrenia.
W Gordon Frankle, Michael Himes, N Scott Mason, Chester A Mathis, Rajesh Narendran

Biol Psychiatry· November 2022

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11C-PiB PET can underestimate brain amyloid-β burden when cotton wool plaques are numerous.
Eric E Abrahamson, Julia K Kofler, Carl R Becker, Julie C Price, Kathy L Newell, Chester A Mathis

Brain· June 2022

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