Publications by authors named "Chih-Lin Hsieh"

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On the mechanism of NPM1 mutations in acute myeloid leukemia.
Michael R Lieber, Chih-Lin Hsieh

Leukemia· October 2025

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Analysis of Naturally Occurring Somatic Insertions in the Human Genome.
Chih-Lin Hsieh, Zarko Manojlovic, Timothy Okitsu, Cindy Okitsu, Jordan Wlodarczyk

bioRxiv· October 2025

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High-depth Whole Genome Sequencing of Single Human Colon Crypts Uncovers New View on Crypt Clonality.
Zarko Manojlovic, Cindy Okitsu, Timothy Okitsu, Jordan Wlodarczyk, Michael R Lieber, Chih-Lin Hsieh

bioRxiv· September 2025

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The RNA tether model for human chromosomal translocation fragile zones.
Di Liu, Chih-Lin Hsieh, Michael R Lieber

Trends Biochem Sci· May 2024

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Construction of high coverage whole-genome sequencing libraries from single colon crypts without DNA extraction or whole-genome amplification.
Zarko Manojlovic, Jordan Wlodarczyk, Cindy Okitsu, Yuxin Jin, David Van Den Berg, Chih-Lin Hsieh

BMC Res Notes· April 2023

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Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.
Heather A Ogana, Samantha Hurwitz, Chih-Lin Hsieh, Huimin Geng, Markus Müschen

Front Cell Dev Biol· March 2023

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The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutation and class switch recombination.
Di Liu, Myron F Goodman, Phuong Pham, Kefei Yu, Chih-Lin Hsieh

DNA Repair (Amst)· February 2022

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Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.
Yongsheng Ruan, Hye Na Kim, Heather A Ogana, Zesheng Wan, Samantha Hurwitz, Chih-Lin Hsieh

Front Oncol· December 2021

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Mechanistic basis for chromosomal translocations at the E2A gene and its broader relevance to human B cell malignancies.
Di Liu, Yong-Hwee Eddie Loh, Chih-Lin Hsieh, Michael R Lieber

Cell Rep· July 2021

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Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer.
Daniel J Schaid, Shannon K McDonnell, Liesel M FitzGerald, Lissa DeRycke, Zachary Fogarty, Chih-Lin Hsieh

Eur Urol· March 2021

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Temporally uncoupled signal and coding joint formation in human V(D)J recombination.
Chih-Lin Hsieh, Cindy Y Okitsu, Michael R Lieber

Mol Immunol· December 2020

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Derivation of induced pluripotent stem cells from ferret somatic cells.
Jinghui Gao, Sophia Petraki, Xingshen Sun, Leonard A Brooks, Thomas J Lynch, Chih-Lin Hsieh

Am J Physiol Lung Cell Mol Physiol· April 2020

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DNA-PKcs chemical inhibition versus genetic mutation: Impact on the junctional repair steps of V(D)J recombination.
Z Anne Esguerra, Go Watanabe, Cindy Y Okitsu, Chih-Lin Hsieh, Michael R Lieber

Mol Immunol· April 2020

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Data-adaptive multi-locus association testing in subjects with arbitrary genealogical relationships.
Gail Gong, Wei Wang, Chih-Lin Hsieh, David J Van Den Berg, Christopher Haiman

Stat Appl Genet Mol Biol· April 2019

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Novel Lines of Evidence for the Asymmetric Strand Displacement Model of Mitochondrial DNA Replication.
Chih-Lin Hsieh

Mol Cell Biol· January 2019

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gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels.
Nicholas B Larson, Shannon McDonnell, Lisa Cannon Albright, Craig Teerlink, Janet Stanford, Chih-Lin Hsieh

Genet Epidemiol· May 2017

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REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants.
Nilah M Ioannidis, Joseph H Rothstein, Vikas Pejaver, Sumit Middha, Shannon K McDonnell, Chih-Lin Hsieh

Am J Hum Genet· October 2016

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Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies.
Nicholas B Larson, Shannon McDonnell, Lisa Cannon Albright, Craig Teerlink, Janet Stanford, Chih-Lin Hsieh

Genet Epidemiol· September 2016

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Effect of CpG dinucleotides within IgH switch region repeats on immunoglobulin class switch recombination.
Zheng Z Zhang, Chih-Lin Hsieh, Cindy Yen Okitsu, Li Han, Kefei Yu

Mol Immunol· August 2015

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Human lymphoid translocation fragile zones are hypomethylated and have accessible chromatin.
Zhengfei Lu, Michael R Lieber, Albert G Tsai, Carolina E Pardo, Markus Müschen, Chih-Lin Hsieh

Mol Cell Biol· April 2015

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Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.
Zheng Z Zhang, Nicholas R Pannunzio, Chih-Lin Hsieh, Kefei Yu, Michael R Lieber

BMC Res Notes· April 2015

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Sensitivity and specificity of immunoprecipitation of DNA containing 5-Methylcytosine.
Cindy Y Okitsu, Chih-Lin Hsieh

BMC Res Notes· March 2015

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The role of G-density in switch region repeats for immunoglobulin class switch recombination.
Zheng Z Zhang, Nicholas R Pannunzio, Chih-Lin Hsieh, Kefei Yu, Michael R Lieber

Nucleic Acids Res· December 2014

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The strength of an Ig switch region is determined by its ability to drive R loop formation and its number of WGCW sites.
Zheng Z Zhang, Nicholas R Pannunzio, Li Han, Chih-Lin Hsieh, Kefei Yu

Cell Rep· July 2014

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DNA ligase I is not essential for mammalian cell viability.
Li Han, Shahnaz Masani, Chih-Lin Hsieh, Kefei Yu

Cell Rep· April 2014

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