Publications by authors named "Ching-Fa Yao"

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Synthesis of 4-Indolylquinoline Bis-Heterocycles from the Reactions of Enone-Tethered Imines with Indoles: Michael/Mannich/Aromatization Sequence.
Weiting Chiu, Sundaram Suresh, Bo-Xun Du, Chia-Yen Kuang, Ching-Fa Yao

J Org Chem· August 2025

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Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells.
Shun-Tzu Chi, Pei-Cih Wei, Ya-Jen Chiu, Te-Hsien Lin, Chih-Hsin Lin, Ching-Fa Yao

J Neurochem· January 2025

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Green Synthesis of Tetrahydropyrazino[2,1-a:5,4-a']diisoquinolines as SARS-CoV-2 Entry Inhibitors.
Sowndarya Palla, Srinivasa Rao Palla, Jia-Jin Liu, Tai-Ling Chao, Ting-Hui Lee, Ching-Fa Yao

ACS Omega· January 2025

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Catalyst-free reactions of anilines with β-chloroenones: synthesis of α-chloroenaminones and 1,4-benzodiazepines.
Sundaram Suresh, Sowndarya Palla, Dai-Ru Chung, Hung-Sheng Chien, Bo-Xun Du, Ching-Fa Yao

Org Biomol Chem· November 2024

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Small Molecules Inducing Autophagic Degradation of Expanded Polyglutamine Protein through Interaction with Both Mutant ATXN3 and LC3.
Te-Hsien Lin, Wan-Ling Chen, Shao-Fan Hsu, I-Cheng Chen, Chih-Hsin Lin, Ching-Fa Yao

Int J Mol Sci· October 2024

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Pd(II)-catalyzed hydroarylations/hydroalkenylations of terminal alkynes: regioselective synthesis of allylic, homoallylic, and 1,3-diene systems.
Jivan Shinde, Sundaram Suresh, Veerababurao Kavala, Ching-Fa Yao

Chem Commun (Camb)· April 2024

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Iodine-Catalyzed Regioselective Synthesis of Diphenyl-Substituted Carbazoles via [4 + 2] Annulation of β-Formyl Ketones with Indoles.
Sundaram Suresh, Hung-Sheng Chien, Chao-Hua Chen, Hao-Yu Tsai, Dai-Ru Chung, Ching-Fa Yao

J Org Chem· December 2023

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Pd-Catalyzed Regioselective (Markovnikov) Addition of Aryl Boronic Acids to Terminal Alkynes of 1,3-Dicarbonyl Compounds and Cyclization/Debenzoylation of Olefinic Dicarbonyl: Access to Arylated Pyran and ()-4-Methylene-1,6-diphenylhex-5-en-1-one.
Jivan Shinde, Veerababurao Kavala, Ching-Fa Yao

Org Lett· September 2023

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Coumarin-chalcone hybrid LM-021 and indole derivative NC009-1 targeting inflammation and oxidative stress to protect BE(2)-M17 cells against α-synuclein toxicity.
Pei-Ning Yang, Wan-Ling Chen, Jun-Wei Lee, Chih-Hsin Lin, Yi-Ru Chen, Ching-Fa Yao

Aging (Albany NY)· August 2023

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One-Pot Knoevenagel/Imination/6π-Azaelectrocyclization Sequence for the Synthesis of Disubstituted Nicotinonitriles.
Li-Chun Lin, Sundaram Suresh, Kun-Wu Lin, Veerababurao Kavala, Ching-Fa Yao

J Org Chem· July 2023

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Iodine-Catalyzed Annulation Reaction of -Formylarylketones with Indoles: A General Strategy for the Synthesis of Indolylbenzo[]carbazoles.
Sundaram Suresh, Veerababurao Kavala, Ching-Fa Yao

J Org Chem· March 2023

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Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson's Disease.
Ya-Jen Chiu, Chih-Hsin Lin, Chung-Yin Lin, Pei-Ning Yang, Yen-Shi Lo, Ching-Fa Yao

Int J Mol Sci· January 2023

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Synthesis of Unsymmetrical Urea Derivatives via Cu-Catalyzed Reaction of Acylazide and Secondary Amine.
Jivan Shinde, Prakash Bhimrao Patil, Veerababurao Kavala, Ching-Fa Yao

Chem Biodivers· August 2022

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A Water-Soluble Rhenium(I) Catalyst for the Regio- and Stereoselective C(sp)-H Alkenylation of -Pyridyl-/-Pyrimidylindole and the N-H Alkenylation of -Pyrimidylaniline Derivatives with Ynamides.
Sundaramoorthi Sarathkumar, Veerababurao Kavala, Ching-Fa Yao

Org Lett· March 2021

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Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation.
Ya-Jen Chiu, Shu-An Lin, Wan-Ling Chen, Te-Hsien Lin, Chih-Hsin Lin, Ching-Fa Yao

Aging (Albany NY)· November 2020

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Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models.
Pei-Cih Wei, Guey-Jen Lee-Chen, Chiung-Mei Chen, Yih-Ru Wu, Yi-Jing Chen, Ching-Fa Yao

Oxid Med Cell Longev· April 2020

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Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer's Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement.
Yi-Chun Chen, Ya-Jen Chiu, Chih-Hsin Lin, Wen-Chuin Hsu, Jia-Lu Wu, Ching-Fa Yao

J Alzheimers Dis· March 2020

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Copper-catalysed synthesis of 3-hydroxyisoindolin-1-ones from benzylcyanide 2-iodobenzamides.
Veerababurao Kavala, Chen-Yu Wang, Cheng-Chuan Wang, Prakash Bhimrao Patil, ChiaChi Fang, Ching-Fa Yao

Org Biomol Chem· February 2020

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A Synthetic Strategy for the Construction of Functionalized Triphenylene Frameworks via Palladium Catalyzed Intramolecular Annulation/Decyanogenative C-H Bond Alkenylation.
Sachin S Ichake, Bharath Kumar Villuri, Sabbasani Rajasekhara Reddy, Veerababurao Kavala, Ching-Fa Yao

Org Lett· April 2019

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Synthesis of Polysubstituted Cyclopentene and Cyclopenta[ b]carbazole Analogues from Unsymmetrical 4-Arylidene-3,6-diarylhex-2-en-5-ynal and Indole Derivatives via an Iodine Mediated Electrocyclization Reaction.
Vijayalakshmi Bandi, Veerababurao Kavala, Ashok Konala, Che-Hao Hsu, Bharath Kumar Villuri, Ching-Fa Yao

J Org Chem· March 2019

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Copper-Catalyzed Cascade Synthesis of 2-Aryl-3-cyanobenzofuran and Dibenzo[ b, f]oxepine-10-carbonitrile Derivatives.
Bharath Kumar Villuri, Sachin S Ichake, Sabbasani Rajasekhara Reddy, Veerababurao Kavala, Vijayalakshmi Bandi, Ching-Fa Yao

J Org Chem· September 2018

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The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice.
Chiung-Mei Chen, Wan-Ling Chen, Chen-Ting Hung, Te-Hsien Lin, Chih-Ying Chao, Ching-Fa Yao

Neurotoxicology· July 2018

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A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells.
Chang-Heng Hsieh, Jing-Ping Wang, Chien-Chih Chiu, Chun-Yen Liu, Ching-Fa Yao

Apoptosis· January 2018

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A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres.
Yu-Ling Ni, Chang-Hung Hsieh, Seung-Hun Kim, Jing-Ping Wang, Chun-Li Su, Ching-Fa Yao

Apoptosis· October 2017

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Synthesis of Benzopyridoindolone Derivatives via a One-Pot Copper Catalyzed Tandem Reaction of 2-Iodobenzamide Derivatives and 2-Iodobenzylcyanides.
Veerababurao Kavala, Zonghan Yang, Ashok Konala, Chia-Yu Huang, Chun-Wei Kuo, Ching-Fa Yao

J Org Chem· July 2017

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