Publications by authors named "Ching-Ju Tsai"

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Dynamic Interactions in the Human βAR Signalling Complex with Mini-G Revealed by NMR.
Philip Rößler, Marco M Ruckstuhl, Arnelle Löbbert, Timo T Stühlinger, Ching-Ju Tsai

J Mol Biol· December 2025

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Tool antibody fragments reveal multiple conformations of the rhodopsin-Gi signaling complex.
Filip Pamula, Oliver Tejero, Jonas Mühle, Ralf Thoma, Gebhard F X Schertler, Ching-Ju Tsai

Biophys J· September 2025

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Active state structures of a bistable visual opsin bound to G proteins.
Oliver Tejero, Filip Pamula, Mitsumasa Koyanagi, Takashi Nagata, Pavel Afanasyev, Ching-Ju Tsai

Nat Commun· October 2024

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Activating an invertebrate bistable opsin with the all-trans 6.11 retinal analog.
Matthew J Rodrigues, Oliver Tejero, Jonas Mühle, Filip Pamula, Ishita Das, Ching-Ju Tsai

Proc Natl Acad Sci U S A· July 2024

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Ultrafast structural changes direct the first molecular events of vision.
Thomas Gruhl, Tobias Weinert, Matthew J Rodrigues, Christopher J Milne, Giorgia Ortolani, Ching-Ju Tsai

Nature· March 2023

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Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
Marc Emmenegger, Elena De Cecco, David Lamparter, Raphaël P B Jacquat, Julien Riou, Ching-Ju Tsai

iScience· February 2023

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Preparation of a stable CCL5·CCR5·G signaling complex for Cryo-EM analysis.
Polina Isaikina, Ching-Ju Tsai, Ivana Petrovic, Marco Rogowski, Alexandra Meng Dürr

Methods Cell Biol· May 2022

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Versatile microporous polymer-based supports for serial macromolecular crystallography.
Isabelle Martiel, John H Beale, Agnieszka Karpik, Chia Ying Huang, Laura Vera, Ching Ju Tsai

Acta Crystallogr D Struct Biol· September 2021

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Biochemical Characterization of GPCR-G Protein Complex Formation.
Filip Pamula, Ching-Ju Tsai

Methods Mol Biol· August 2021

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High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs.
Na Wu, Agnieszka M Olechwier, Cyrill Brunner, Patricia C Edwards, Ching-Ju Tsai

Proc Natl Acad Sci U S A· August 2021

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Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist.
Polina Isaikina, Ching-Ju Tsai, Nikolaus Dietz, Filip Pamula, Anne Grahl

Sci Adv· June 2021

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GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy.
Philip Rößler, Daniel Mayer, Ching-Ju Tsai, Dmitry B Veprintsev, Gebhard F X Schertler

Molecules· December 2020

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Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization.
Filip Pamula, Jonas Mühle, Alain Blanc, Rony Nehmé, Patricia C Edwards, Ching-Ju Tsai

J Vis Exp· March 2020

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Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to Nanofibers.
Jesús Del Barrio, Ji Liu, Ryan A Brady, Cindy S Y Tan, Stefano Chiodini, Ching-Ju Tsai

J Am Chem Soc· September 2019

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Chinese Herbal Medicine Displays Potential Anti-Cancer Efficacy on Metastatic Prostate Cancer Cells.
Wen-Chin Huang, Meng-Shiun Chang, Shih-Yin Huang, Ching-Ju Tsai, Pin-Hung Kuo

Int J Mol Sci· September 2019

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Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit.
Ching-Ju Tsai, Jacopo Marino, Ricardo Adaixo, Filip Pamula, Jonas Muehle

Elife· June 2019

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Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals.
Cecilia M Casadei, Karol Nass, Anton Barty, Mark S Hunter, Celestino Padeste, Ching-Ju Tsai

IUCrJ· January 2019

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Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity.
Ching-Ju Tsai, Filip Pamula, Rony Nehmé, Jonas Mühle, Tobias Weinert

Sci Adv· September 2018

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Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals.
Cecilia M Casadei, Ching-Ju Tsai, Anton Barty, Mark S Hunter, Nadia A Zatsepin

IUCrJ· January 2018

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Structural biology: Signalling under the microscope.
Ching-Ju Tsai, Joerg Standfuss, Robert M Glaeser

Nature· June 2017

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Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor.
Shin Isogai, Xavier Deupi, Christian Opitz, Franziska M Heydenreich, Ching-Ju Tsai

Nature· February 2016

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Time-resolved structural studies with serial crystallography: A new light on retinal proteins.
Valérie Panneels, Wenting Wu, Ching-Ju Tsai, Przemek Nogly, Jan Rheinberger

Struct Dyn· July 2015

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7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source.
Bill Pedrini, Ching-Ju Tsai, Guido Capitani, Celestino Padeste, Mark S Hunter

Philos Trans R Soc Lond B Biol Sci· July 2014

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Femtosecond X-ray diffraction from two-dimensional protein crystals.
Matthias Frank, David B Carlson, Mark S Hunter, Garth J Williams, Marc Messerschmidt, Ching-Ju Tsai

IUCrJ· March 2014

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Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes.
Yi Li, Stephen Hsueh-Jeng Lu, Ching-Ju Tsai, Christopher Bohm, Seema Qamar

Structure· January 2014

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