Publications by authors named "Chris Freeden"

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Solvent-Casted Films to Assist Polymer Selection for Amorphous Solid Dispersions During Preclinical Studies: In-vitro and In-vivo Exploration.
Laura I Mosquera-Giraldo, Maria Donoso, Kevin Stefanski, Kimberly Foster, Christoph Gesenberg, Chris Freeden

Pharm Res· May 2021

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Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone.
Yaofeng Cheng, Shenjue Chen, Chris Freeden, Weiqi Chen, Yueping Zhang

J Pharmacol Exp Ther· September 2017

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Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
Yaofeng Cheng, Chris Freeden, Yueping Zhang, Pamela Abraham, Hong Shen

Biopharm Drug Dispos· July 2016

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Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species.
Hong Shen, Jun Dai, Tongtong Liu, Yaofeng Cheng, Weiqi Chen, Chris Freeden

J Pharmacol Exp Ther· May 2016

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Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.
Pratik Devasthale, Wei Wang, James Mignone, Kishore Renduchintala, Sridhar Radhakrishnan, Chris Freeden

Bioorg Med Chem Lett· October 2015

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Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup.
Pratik Devasthale, Wei Wang, Andres S Hernandez, Fang Moore, Kishore Renduchintala, Chris Freeden

Bioorg Med Chem Lett· July 2015

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Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats.
Murali Subramanian, Vishwanath Kurawattimath, Krishna Pocha, Chris Freeden, Indranil Rao

Xenobiotica· December 2014

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Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate.
William N Washburn, Mark Manfredi, Pratik Devasthale, Guohua Zhao, Saleem Ahmad, Chris Freeden

J Med Chem· September 2014

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