Publications by authors named "Chris Luscombe"

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BRADSHAW: a system for automated molecular design.
Darren V S Green, Stephen Pickett, Chris Luscombe, Stefan Senger, David Marcus

J Comput Aided Mol Des· July 2020

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Correction to: BRADSHAW: a system for automated molecular design.
Darren V S Green, Stephen Pickett, Chris Luscombe, Stefan Senger, David Marcus

J Comput Aided Mol Des· July 2020

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The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition.
Daniel F Price, Chris N Luscombe, Peter J Eddershaw, Chris D Edwards, Mark Gumbleton

Pharm Res· December 2017

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Development of a Novel Quantitative Structure-Activity Relationship Model to Accurately Predict Pulmonary Absorption and Replace Routine Use of the Isolated Perfused Respiring Rat Lung Model.
Chris D Edwards, Chris Luscombe, Peter Eddershaw, Edith M Hessel

Pharm Res· November 2016

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Evaluation of an in silico cardiac safety assay: using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge.
Kylie A Beattie, Chris Luscombe, Geoff Williams, Jordi Munoz-Muriedas, David J Gavaghan

J Pharmacol Toxicol Methods· February 2014

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Quantitative relationship between rat intestinal absorption and Abraham descriptors.
Yuan H Zhao, Michael H Abraham, Anne Hersey, Chris N Luscombe

Eur J Med Chem· August 2004

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Bile salt/lecithin mixed micelles optimized for the solubilization of a poorly soluble steroid molecule using statistical experimental design.
Gavin A Magee, Jane French, Bob Gibbon, Chris Luscombe

Drug Dev Ind Pharm· April 2003

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Evaluation of rat intestinal absorption data and correlation with human intestinal absorption.
Yuan H Zhao, Michael H Abraham, Joelle Le, Anne Hersey, Chris N Luscombe

Eur J Med Chem· March 2003

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Rate-limited steps of human oral absorption and QSAR studies.
Yuan H Zhao, Michael H Abraham, Joelle Le, Anne Hersey, Chris N Luscombe

Pharm Res· October 2002

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