Publications by authors named "Chris Tarling"

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Potent Human α-Amylase Inhibition by the β-Defensin-like Protein Helianthamide.
Christina Tysoe, Leslie K Williams, Robert Keyzers, Nham T Nguyen, Chris Tarling

ACS Cent Sci· March 2016

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Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones.
Georg Schitter, Andreas J Steiner, Gerit Pototschnig, Elisabeth Scheucher, Martin Thonhofer, Chris A Tarling

Chembiochem· September 2010

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Synthesis and biological evaluation of novel biotin-iminoalditol conjugates.
Gerit Pototschnig, Christian Morales De Csáky, Jose R Montenegro Burke, Georg Schitter, Arnold E Stütz, Chris A Tarling

Bioorg Med Chem Lett· July 2010

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Chitinase inhibition by chitobiose and chitotriose thiazolines.
James M Macdonald, Chris A Tarling, Edward J Taylor, Rebecca J Dennis, David S Myers

Angew Chem Int Ed Engl· March 2010

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Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors.
Georg Schitter, Elisabeth Scheucher, Andreas J Steiner, Arnold E Stütz, Martin Thonhofer, Chris A Tarling

Beilstein J Org Chem· March 2010

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2-Acetamino-1,2-dideoxynojirimycin-lysine hybrids as hexosaminidase inhibitors.
Andreas J Steiner, Georg Schitter, Arnold E Stütz, Tanja M Wrodnigg, Chris A Tarling

Tetrahedron Asymmetry· May 2009

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1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.
Andreas J Steiner, Georg Schitter, Arnold E Stütz, Tanja M Wrodnigg, Chris A Tarling

Bioorg Med Chem· December 2008

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High-throughput screening of cell lysates for ganglioside synthesis.
Susan M Hancock, Chris A Tarling, Stephen G Withers

Anal Biochem· November 2008

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Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Douglas A Kuntz, Chris A Tarling, Stephen G Withers, David R Rose

Biochemistry· September 2008

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Glycosidase profiling with immobilised glycosidase-inhibiting iminoalditols--a proof-of-concept study.
Andreas J Steiner, Arnold E Stütz, Tanja M Wrodnigg, Chris A Tarling, Stephen G Withers

Bioorg Med Chem Lett· March 2008

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The search for novel human pancreatic alpha-amylase inhibitors: high-throughput screening of terrestrial and marine natural product extracts.
Chris A Tarling, Kate Woods, Ran Zhang, Harry C Brastianos, Gary D Brayer

Chembiochem· February 2008

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Iminoalditol-amino acid hybrids: synthesis and evaluation as glycosidase inhibitors.
Andreas J Steiner, Arnold E Stütz, Chris A Tarling, Stephen G Withers, Tanja M Wrodnigg

Carbohydr Res· September 2007

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The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
Matthew E C Caines, Susan M Hancock, Chris A Tarling, Tanja M Wrodnigg, Robert V Stick

Angew Chem Int Ed Engl· September 2007

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Recruitment of both uniform and differential binding energy in enzymatic catalysis: xylanases from families 10 and 11.
Jacqueline Wicki, Johann Schloegl, Chris A Tarling, Stephen G Withers

Biochemistry· June 2007

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Probing electrostatic interactions along the reaction pathway of a glycoside hydrolase: histidine characterization by NMR spectroscopy.
Mario Schubert, David K Y Poon, Jacqueline Wicki, Chris A Tarling, Emily M Kwan

Biochemistry· June 2007

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Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms.
Matthew E C Caines, Mark D Vaughan, Chris A Tarling, Susan M Hancock, R Antony J Warren

J Biol Chem· May 2007

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Fine tuning of beta-glucosidase inhibitory activity in the 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) system.
Tanja M Wrodnigg, Arnold E Stütz, Chris A Tarling, Stephen G Withers

Carbohydr Res· July 2006

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X-ray crystal structures of rabbit N-acetylglucosaminyltransferase I (GnT I) in complex with donor substrate analogues.
Roni D Gordon, Prashanth Sivarajah, Malathy Satkunarajah, Dengbo Ma, Chris A Tarling

J Mol Biol· June 2006

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Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.
Peter Greimel, Herwig Häusler, Inge Lundt, Karen Rupitz, Arnold E Stütz, Chris A Tarling

Bioorg Med Chem Lett· April 2006

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Fluorescently tagged iminoalditol glycosidase inhibitors as novel biological probes and diagnostics.
Inge Lundt, Andreas J Steiner, Arnold E Stütz, Chris A Tarling, Stefan Ully

Bioorg Med Chem· March 2006

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Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification.
Wendy Offen, Carlos Martinez-Fleites, Min Yang, Eng Kiat-Lim, Benjamin G Davis, Chris A Tarling

EMBO J· March 2006

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Evaluation of a new system for developing particulate enzymes based on the surface (S)-layer protein (RsaA) of Caulobacter crescentus: fusion with the beta-1,4-glycanase (Cex) from the cellulolytic bacterium Cellulomonas fimi yields a robust, catalytically active product.
Gillian Duncan, Chris A Tarling, Wade H Bingle, John F Nomellini, Mat Yamage

Appl Biochem Biotechnol· November 2005

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Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases.
Tracey M Gloster, James M Macdonald, Chris A Tarling, Robert V Stick, Stephen G Withers

J Biol Chem· November 2004

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The synthesis of a series of modified mannotrisaccharides as probes of the enzymes involved in the early stages of mammalian complex N-glycan formation.
Chris A Tarling, Stephen G Withers

Carbohydr Res· October 2004

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Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A.
Tracey M Gloster, Spencer J Williams, Shirley Roberts, Chris A Tarling, Jacqueline Wicki

Chem Commun (Camb)· August 2004

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