Publications by authors named "Christian Haass"

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Basic Science and Pathogenesis.
Pablo Zaragoza-Ballester, Briggitte Nuscher, Daniel Alcolea, Álex Fernández-León, Íñigo Rodríguez-Baz, Christian Haass

Alzheimers Dement· December 2025

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"The DESCRIBE-ALS-FTD study: a prospective multicenter observational study of the ALS-FTD spectrum".
Andreas Hermann, Johannes Prudlo, Elisabeth Kasper, Matthis Synofzik, Oliver Peters, Christian Haass

Amyotroph Lateral Scler Frontotemporal Degener· November 2025

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Image-Derived Blood Normalization of Antibody-Based TREM2 PET in Mouse Models of Amyloidosis and Myocardial Infarction.
Rebecca Schaefer, Lea H Kunze, Marlies Haertel, Yeqian Zhu, Kai Schlepckow, Christian Haass

J Nucl Med· September 2025

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Early intervention anti-Aβ immunotherapy attenuates microglial activation without inducing exhaustion at residual plaques.
Lis de Weerd, Selina Hummel, Stephan A Müller, Iñaki Paris, Thomas Sandmann, Christian Haass

Mol Neurodegener· August 2025

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The late-onset Alzheimer's disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis.
Georg Jocher, Gozde Ozcelik, Stephan A Müller, Hung-En Hsia, Miranda Lastra Osua, Christian Haass

Life Sci Alliance· May 2025

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The regulatory rollercoaster continues-EMA refuses donanemab.
Bart De Strooper, Christian Haass, John Hardy, Henrik Zetterberg

Lancet· May 2025

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Monoallelic TYROBP deletion is a novel risk factor for Alzheimer's disease.
Henna Martiskainen, Roosa-Maria Willman, Päivi Harju, Sami Heikkinen, Mette Heiskanen, Christian Haass

Mol Neurodegener· April 2025

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The protective PLCγ2-P522R variant mitigates Alzheimer's disease-associated pathologies by enhancing beneficial microglial functions.
Mari Takalo, Heli Jeskanen, Taisia Rolova, Inka Kervinen, Marianna Hellén, Christian Haass

J Neuroinflammation· March 2025

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Female sex is linked to a stronger association between sTREM2 and CSF p-tau in Alzheimer's disease.
Davina Biel, Marc Suárez-Calvet, Anna Dewenter, Anna Steward, Sebastian N Roemer, Christian Haass

EMBO Mol Med· February 2025

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Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Seiji Kaji, Stefan A Berghoff, Lena Spieth, Lennart Schlaphoff, Andrew O Sasmita, Christian Haass

Immunity· January 2025

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Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Seiji Kaji, Stefan A Berghoff, Lena Spieth, Lennart Schlaphoff, Andrew O Sasmita, Christian Haass

Immunity· November 2024

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Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice.
Wenli Liu, Brian D Hardaway, Eunyoung Kim, Jessica Pauli, Justus Leonard Wettich, Christian Haass

J Clin Invest· November 2024

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Divisions over the regulation of lecanemab.
Bart De Strooper, Christian Haass, John Hardy, Henrik Zetterberg

Lancet· November 2024

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GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA).
Sabrina Katzdobler, Georg Nübling, Martin Klietz, Urban M Fietzek, Carla Palleis, Christian Haass

J Neurol· October 2024

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Correction to: Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
Kohji Mori, Thomas Arzberger, Friedrich A Grässer, Ilse Gijselinck, Stephanie May, Christian Haass

Acta Neuropathol· October 2024

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PET imaging of microglia in Alzheimer's disease using copper-64 labeled TREM2 antibodies.
Monireh Shojaei, Rebecca Schaefer, Kai Schlepckow, Lea H Kunze, Felix L Struebing, Christian Haass

Theranostics· October 2024

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Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Christian Haass

Nat Neurosci· September 2024

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Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease.
Artem Zatcepin, Johannes Gnörich, Boris-Stephan Rauchmann, Laura M Bartos, Stephan Wagner, Christian Haass

Mol Neurodegener· September 2024

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Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
Henrick Riemenschneider, Qiang Guo, Jakob Bader, Frédéric Frottin, Daniel Farny, Christian Haass

EMBO Rep· July 2024

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Physiological roles of α-synuclein serine-129 phosphorylation - not an oxymoron.
Nagendran Ramalingam, Christian Haass, Ulf Dettmer

Trends Neurosci· July 2024

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Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration.
Marvin Reich, Matthew J Simon, Beate Polke, Iñaki Paris, Georg Werner, Christian Haass

Sci Transl Med· June 2024

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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
Yiying Hu, Alexander Hruscha, Chenchen Pan, Martina Schifferer, Michael K Schmidt, Christian Haass

Mol Neurodegener· June 2024

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Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging.
Katalin Todorov-Völgyi, Judit González-Gallego, Stephan A Müller, Nathalie Beaufort, Rainer Malik, Christian Haass

Nat Aging· April 2024

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Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2.
Chen Yu, Eleonora M Lad, Rose Mathew, Nobuhiko Shiraki, Sejiro Littleton, Christian Haass

J Exp Med· March 2024

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TREM2 protects from atherosclerosis by limiting necrotic core formation.
Marie Piollet, Florentina Porsch, Giuseppe Rizzo, Frederieke Kapser, Dirk J J Schulz, Christian Haass

Nat Cardiovasc Res· March 2024

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