Publications by authors named "Daniel Farny"

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Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
Ali Rezaei, Virág Kocsis-Jutka, Zeynep I Gunes, Qing Zeng, Georg Kislinger, Daniel Farny

Nat Commun· April 2025

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Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
Henrick Riemenschneider, Qiang Guo, Jakob Bader, Frédéric Frottin, Daniel Farny

EMBO Rep· July 2024

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Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Henrick Riemenschneider, Francesca Simonetti, Udit Sheth, Eszter Katona, Stefan Roth, Daniel Farny

Acta Neuropathol Commun· July 2023

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Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
Henrick Riemenschneider, Qiang Guo, Jakob Bader, Frédéric Frottin, Daniel Farny

EMBO Rep· June 2022

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Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (GC) expression in C9orf72 ALS/FTD.
Mareike Czuppa, Ashutosh Dhingra, Qihui Zhou, Carina Schludi, Laura König, Daniel Farny

Cell Rep· June 2022

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Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill, Daniel Farny

Acta Neuropathol· August 2020

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Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Bahram Khosravi, Kathrine D LaClair, Henrick Riemenschneider, Qihui Zhou, Frédéric Frottin, Daniel Farny

EMBO J· April 2020

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Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl, Daniel Farny

EMBO Mol Med· February 2020

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Proteomics and neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
Hannelore Hartmann, Daniel Hornburg, Mareike Czuppa, Jakob Bader, Meike Michaelsen, Daniel Farny

Life Sci Alliance· May 2018

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Antibodies inhibit transmission and aggregation of poly-GA dipeptide repeat proteins.
Qihui Zhou, Carina Lehmer, Meike Michaelsen, Kohji Mori, Dominik Alterauge, Daniel Farny

EMBO Mol Med· May 2017

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