Publications by authors named "Christian Hildmann"

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Assessing the cooling potential of climate change adaptation measures in rural areas.
Beate Zimmermann, Sarah Kruber, Claas Nendel, Henry Munack, Christian Hildmann

J Environ Manage· August 2024

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Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases.
Daniel Riester, Christian Hildmann, Patricia Haus, Antonia Galetovic, Andreas Schober

Bioorg Med Chem Lett· July 2009

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HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells.
Dennis Wegener, Hedwig E Deubzer, Ina Oehme, Till Milde, Christian Hildmann

Anticancer Drugs· October 2008

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Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.
Dennis Wegener, Christian Hildmann, Daniel Riester, Andreas Schober, Franz-Josef Meyer-Almes

Biochem J· July 2008

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Inhibitor-mediated stabilization of the conformational structure of a histone deacetylase-like amidohydrolase.
Stefanie Kern, Daniel Riester, Christian Hildmann, Andreas Schwienhorst, Franz-Josef Meyer-Almes

FEBS J· July 2007

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Histone deacetylase inhibitors--turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases.
Daniel Riester, Christian Hildmann, Andreas Schwienhorst

Appl Microbiol Biotechnol· June 2007

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Histone deacetylases--an important class of cellular regulators with a variety of functions.
Christian Hildmann, Daniel Riester, Andreas Schwienhorst

Appl Microbiol Biotechnol· June 2007

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Factors affecting the substrate specificity of histone deacetylases.
Daniel Riester, Christian Hildmann, Sylvia Grünewald, Thomas Beckers, Andreas Schwienhorst

Biochem Biophys Res Commun· June 2007

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Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor.
Tine Kragh Nielsen, Christian Hildmann, Daniel Riester, Dennis Wegener, Andreas Schwienhorst

Acta Crystallogr Sect F Struct Biol Cryst Commun· April 2007

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Histone deacetylase inhibitor assay based on fluorescence resonance energy transfer.
Daniel Riester, Christian Hildmann, Andreas Schwienhorst, Franz-Josef Meyer-Almes

Anal Biochem· March 2007

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An active site tyrosine residue is essential for amidohydrolase but not for esterase activity of a class 2 histone deacetylase-like bacterial enzyme.
Kristin Moreth, Daniel Riester, Christian Hildmann, René Hempel, Dennis Wegener

Biochem J· February 2007

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Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases.
Christian Hildmann, Dennis Wegener, Daniel Riester, René Hempel, Andreas Schober

J Biotechnol· June 2006

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Crystal structure of a bacterial class 2 histone deacetylase homologue.
Tine Kragh Nielsen, Christian Hildmann, Achim Dickmanns, Andreas Schwienhorst, Ralf Ficner

J Mol Biol· November 2005

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Recent progress in the development of assays suited for histone deacetylase inhibitor screening.
Dennis Wegener, Christian Hildmann, Andreas Schwienhorst

Mol Genet Metab· November 2004

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Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates.
Daniel Riester, Dennis Wegener, Christian Hildmann, Andreas Schwienhorst

Biochem Biophys Res Commun· November 2004

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A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases.
Christian Hildmann, Milena Ninkovic, Rüdiger Dietrich, Dennis Wegener, Daniel Riester

J Bacteriol· April 2004

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Directed evolution towards protease-resistant hirudin variants.
Frank Wirsching, Martina Keller, Christian Hildmann, Daniel Riester, Andreas Schwienhorst

Mol Genet Metab· December 2003

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Improved fluorogenic histone deacetylase assay for high-throughput-screening applications.
Dennis Wegener, Christian Hildmann, Daniel Riester, Andreas Schwienhorst

Anal Biochem· October 2003

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