Publications by authors named "Christian Loch"

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Necroptosis blockade prevents lung injury in severe influenza.
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Christian Loch

Nature· April 2024

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Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Chinnaswamy Tiruppathi, Dong-Mei Wang, Mohammad Owais Ansari, Shabana Bano, Yoshikazu Tsukasaki, Christian Loch

Nat Commun· October 2023

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Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining.
Maria Jose Cabello-Lobato, Matthew Jenner, Metztli Cisneros-Aguirre, Kira Brüninghoff, Zac Sandy, Christian M Loch

Nucleic Acids Res· May 2022

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Synthesis and pharmacological evaluation of [F]PBR316: a novel PET ligand targeting the translocator protein 18 kDa (TSPO) with low binding sensitivity to human single nucleotide polymorphism rs6971.
Filomena Mattner, Andrew Katsifis, Thomas Bourdier, Christian Loc'h, Paula Berghofer

RSC Med Chem· July 2021

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The newly established bovine endometrial gland cell line (BEGC) forms gland acini in vitro and is only IFNτ-responsive (MAPK42/44 activation) after E and P-pre-incubation.
Jan-Dirk Haeger, Christian Loch, Christiane Pfarrer

Placenta· July 2018

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Simulation of drug distribution in the vitreous body after local drug application into intact vitreous body and in progress of posterior vitreous detachment.
Christian Loch, Malte Bogdahn, Sandra Stein, Stefan Nagel, Rudolf Guthoff

J Pharm Sci· February 2014

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A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate.
Christian M Loch, James E Strickler

Biochim Biophys Acta· November 2012

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Ubiquitin drug discovery and diagnostics.
Christian Loch, Michael Eddins

Biochim Biophys Acta· November 2012

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PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy.
Stefanie Dedeurwaerdere, Paul D Callaghan, Tien Pham, Gita L Rahardjo, Halima Amhaoul

EJNMMI Res· November 2012

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Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes.
Christian Loch, Simon Zakelj, Albin Kristl, Stefan Nagel, Rudolf Guthoff

Eur J Pharm Sci· August 2012

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Radiation dosimetry of the translocator protein ligands [18F]PBR111 and [18F]PBR102.
Jordan D Verschuer, Jocelyn Towson, Stefan Eberl, Andrew Katsifis, David Henderson

Nucl Med Biol· July 2012

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Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and lysosomal targeting of plasma membrane KCa3.1.
Corina M Balut, Christian M Loch, Daniel C Devor

FASEB J· November 2011

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Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates.
Christian M Loch, Michael J Eddins, James E Strickler

Cell Biochem Biophys· June 2011

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Deubiquitylase, deSUMOylase, and deISGylase activity microarrays for assay of substrate preference and functional modifiers.
Christian M Loch, Charles L Cuccherini, Craig A Leach, James E Strickler

Mol Cell Proteomics· January 2011

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A rapid solid-phase extraction method for measurement of non-metabolised peripheral benzodiazepine receptor ligands, [(18)F]PBR102 and [(18)F]PBR111, in rat and primate plasma.
Andrew Katsifis, Christian Loc'h, David Henderson, Thomas Bourdier, Tien Pham

Nucl Med Biol· January 2011

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Use of a single-chain antibody library for ovarian cancer biomarker discovery.
Arturo B Ramirez, Christian M Loch, Yuzheng Zhang, Yan Liu, Xiaohong Wang

Mol Cell Proteomics· July 2010

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Discovery of [18F]N-(2-(diethylamino)ethyl)-6-fluoronicotinamide: a melanoma positron emission tomography imaging radiotracer with high tumor to body contrast ratio and rapid renal clearance.
Ivan Greguric, Stephen R Taylor, Delphine Denoyer, Patrice Ballantyne, Paula Berghofer

J Med Chem· September 2009

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In-vivo imaging characteristics of two fluorinated flumazenil radiotracers in the rat.
Stefanie Dedeurwaerdere, Marie-Claude Gregoire, Lucy Vivash, Peter Roselt, David Binns

Eur J Nucl Med Mol Imaging· June 2009

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Synthesis and evaluation of novel radioiodinated nicotinamides for malignant melanoma.
Xiang Liu, Tien Q Pham, Paula Berghofer, Janette Chapman, Ivan Greguric

Nucl Med Biol· October 2008

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Synthesis and biological evaluation of substituted [18F]imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography.
Christopher J R Fookes, Tien Q Pham, Filomena Mattner, Ivan Greguric, Christian Loc'h

J Med Chem· July 2008

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Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery.
Nathalie Scholler, Jennifer A Gross, Barbara Garvik, Lance Wells, Yan Liu, Christian M Loch

J Transl Med· July 2008

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Intrapartum fever and chorioamnionitis as risks for encephalopathy in term newborns: a case-control study.
Heidi K Blume, Christopher I Li, Christian M Loch, Thomas D Koepsell

Dev Med Child Neurol· January 2008

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Use of high density antibody arrays to validate and discover cancer serum biomarkers.
Christian M Loch, Arturo B Ramirez, Yan Liu, Cassandra L Sather, Jeffrey J Delrow

Mol Oncol· December 2007

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Preparation and biologic evaluation of a novel radioiodinated benzylpiperazine, 123I-MEL037, for malignant melanoma.
Tien Q Pham, Paula Berghofer, Xiang Liu, Ivan Greguric, Branko Dikic

J Nucl Med· August 2007

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Neonatal encephalopathy and socioeconomic status: population-based case-control study.
Heidi K Blume, Christian M Loch, Christopher I Li

Arch Pediatr Adolesc Med· July 2007

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