Publications by authors named "Michael Eddins"

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Structural Characterization of Linker Shielding in ADC Site-Specific Conjugates.
Maru Jaime-Garza, Andrew Waight, Manish Hudlikar, Michael J Eddins, Elnaz S Rasti

Pharmaceutics· December 2025

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Highly Diastereoselective Access to Densely Functionalized Piperidine Cores of Influenza Endonuclease Inhibitors via a Metal-Free S1 Approach.
Yonglian Zhang, Chunrui Sun, Liangqin Guo, Kake Zhao, Frank Bennett, Michael J Eddins

J Org Chem· January 2025

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Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
Xiao Xiao, Zhiyun Wen, Qing Chen, Jennifer M Shipman, James Kostas, Michael J Eddins

J Virol· December 2023

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Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.
Scott A Hollingsworth, Cameron L Noland, Karin Vroom, Anasuya Saha, Miranda Sam, Michael Eddins

Sci Rep· August 2023

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Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins

Commun Biol· June 2023

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Profiling of hMPV F-specific antibodies isolated from human memory B cells.
Xiao Xiao, Arthur Fridman, Lu Zhang, Pavlo Pristatsky, Eberhard Durr, Michael J Eddins

Nat Commun· May 2022

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Discovery of a new class of integrin antibodies for fibrosis.
Ji Zhang, Tao Wang, Ashmita Saigal, Josephine Johnson, Jennifer Morrisson, Michael J Eddins

Sci Rep· January 2021

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A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Aimin Tang, Zhifeng Chen, Kara S Cox, Hua-Poo Su, Cheryl Callahan, Michael Eddins

Nat Commun· September 2019

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The modern Fontan operation shows no increase in mortality out to 20 years: a new paradigm.
Robert J Dabal, James K Kirklin, Manisha Kukreja, Robert N Brown, David C Cleveland, Michael C Eddins

J Thorac Cardiovasc Surg· December 2014

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Comprehensive ubiquitin E2 profiling of ten ubiquitin E3 ligases.
Jeffrey G Marblestone, Samir Butt, Devin M McKelvey, David E Sterner, Michael R Mattern, Michael J Eddins

Cell Biochem Biophys· September 2013

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Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases.
Steven J Orcutt, Jian Wu, Michael J Eddins, Craig A Leach, James E Strickler

Biochim Biophys Acta· November 2012

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Ubiquitin drug discovery and diagnostics.
Christian Loch, Michael Eddins

Biochim Biophys Acta· November 2012

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Targeting the ubiquitin E3 ligase MuRF1 to inhibit muscle atrophy.
Michael J Eddins, Jeffrey G Marblestone, K G Suresh Kumar, Craig A Leach, David E Sterner

Cell Biochem Biophys· June 2011

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Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates.
Christian M Loch, Michael J Eddins, James E Strickler

Cell Biochem Biophys· June 2011

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Novel approach for characterizing ubiquitin E3 ligase function.
Jeffrey G Marblestone, K G Suresh Kumar, Michael J Eddins, Craig A Leach, David E Sterner

J Biomol Screen· December 2010

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Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH.
Michael J Eddins, Ranjani Varadan, David Fushman, Cecile M Pickart, Cynthia Wolberger

J Mol Biol· March 2007

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Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
Michael J Eddins, Candice M Carlile, Kamila M Gomez, Cecile M Pickart, Cynthia Wolberger

Nat Struct Mol Biol· October 2006

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Ubiquitin: structures, functions, mechanisms.
Cecile M Pickart, Michael J Eddins

Biochim Biophys Acta· November 2004

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A conserved catalytic residue in the ubiquitin-conjugating enzyme family.
Pei-Ying Wu, Mary Hanlon, Michael Eddins, Colleen Tsui, Richard S Rogers

EMBO J· October 2003

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Crystallization and low-resolution structure of an effector-caspase/P35 complex: similarities and differences to an initiator-caspase/P35 complex.
Michael J Eddins, Donna Lemongello, Paul D Friesen, Andrew J Fisher

Acta Crystallogr D Biol Crystallogr· February 2002

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