Publications by authors named "Kake Zhao"

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Highly Diastereoselective Access to Densely Functionalized Piperidine Cores of Influenza Endonuclease Inhibitors via a Metal-Free S1 Approach.
Yonglian Zhang, Chunrui Sun, Liangqin Guo, Kake Zhao, Frank Bennett

J Org Chem· January 2025

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Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties.
Petr Vachal, Joseph L Duffy, Louis-Charles Campeau, Rupesh P Amin, Kaushik Mitra, Kake Zhao

J Med Chem· September 2021

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, Pravien Abeywickrema, Vijayalakshmi Agnani, Kake Zhao

Cell Chem Biol· February 2021

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, Pravien Abeywickrema, Vijayalakshmi Agnani, Kake Zhao

Cell Chem Biol· January 2020

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Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach.
Jonathan E Wilson, Ravi Kurukulasuriya, Mikhail Reibarkh, Maud Reiter, Aaron Zwicker, Kake Zhao

ACS Med Chem Lett· March 2016

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Design of potent and selective GPR119 agonists for type II diabetes.
Jason W Szewczyk, John Acton, Alan D Adams, Gary Chicchi, Stanley Freeman, Kake Zhao

Bioorg Med Chem Lett· May 2011

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Substituted indanylacetic acids as PPAR-alpha-gamma activators.
Derek B Lowe, Neil Bifulco, William H Bullock, Thomas Claus, Philip Coish, Kake Zhao, Qian Zhao

Bioorg Med Chem Lett· January 2006

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Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic.
Kake Zhao, Dong Sung Lim, Takashi Funaki, John T Welch

Bioorg Med Chem· January 2003

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