Publications by authors named "Christian Scheerans"

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Polycystic ovary syndrome and elevated body mass index independently increase type 2 diabetes risk with obesity-mediated risk dominating: a real-world data analysis of US patients.
Konstantin Sharafutdinov, Jan Hilpert, Rolf Burghaus, Christian Diedrich, Jörg Lippert, Christian Scheerans

Fertil Steril· September 2025

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Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men.
Christian Friedrich, Dave Singh, Klaus Francke, Stefan Klein, Terence Hetzel, Christian Scheerans

Br J Clin Pharmacol· August 2024

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Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis.
Jan Hilpert, Esther Groettrup-Wolfers, Hristiyan Kosturski, Laura Bennett, Catriona L K Barnes, Christian Scheerans

Drugs R D· September 2023

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Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study.
Isabella Gashaw, Stefanie Reif, Herbert Wiesinger, Andreas Kaiser, Frank S Zollmann, Christian Scheerans

Eur J Endocrinol· July 2023

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Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study.
Christian Friedrich, Klaus Francke, Isabella Gashaw, Christian Scheerans, Stefan Klein

Clin Pharmacokinet· August 2022

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Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.
Vijayalakshmi Chelliah, Georgia Lazarou, Sumit Bhatnagar, John P Gibbs, Marjoleen Nijsen, Christian Scheerans

Clin Pharmacol Ther· March 2021

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Proposal for defining the relevance of drug accumulation derived from single dose study data for modified release dosage forms.
Christian Scheerans, Roland Heinig, Wolfgang Mueck

Biopharm Drug Dispos· March 2015

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Concentration-response studies and modelling of the pharmacodynamics of linezolid: Staphylococcus aureus versus Enterococcus faecium.
Christian Scheerans, Sebastian G Wicha, Julia Michael, Hartmut Derendorf, Charlotte Kloft

Int J Antimicrob Agents· January 2015

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Pharmacokinetics of the soluble guanylate cyclase activator cinaciguat in individuals with hepatic impairment.
Reiner Frey, Christian Scheerans, Martin Blunck, Wolfgang Mück, Mark Jean Gnoth

J Clin Pharmacol· November 2012

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Assessment of the effects of renal impairment on the pharmacokinetics of the soluble guanylate cyclase activator cinaciguat after a single intravenous dose.
John T Lettieri, Christian Scheerans, Martin Blunck, Arthur L Mazzu, Reiner Frey

J Clin Pharmacol· August 2012

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Compliance assessment of ambulatory Alzheimer patients to aid therapeutic decisions by healthcare professionals.
Oliver Schwalbe, Christian Scheerans, Ines Freiberg, Andrea Schmidt-Pokrzywniak, Andreas Stang

BMC Health Serv Res· August 2010

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In vitro pharmacodynamic models to determine the effect of antibacterial drugs.
Julia Gloede, Christian Scheerans, Hartmut Derendorf, Charlotte Kloft

J Antimicrob Chemother· February 2010

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Proposal for a standardised identification of the mono-exponential terminal phase for orally administered drugs.
Christian Scheerans, Hartmut Derendorf, Charlotte Kloft

Biopharm Drug Dispos· April 2008

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