Publications by authors named "Christoph Scheich"

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Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.
Frank Herrmann, Manuela Hessmann, Sabine Schaertl, Karola Berg-Rosseburg, Christopher J Brown, Christoph Scheich

Sci Rep· September 2021

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[C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins.
Longbin Liu, Peter D Johnson, Michael E Prime, Vinod Khetarpal, Matthew R Lee, Christoph Scheich

J Med Chem· August 2021

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Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.
Longbin Liu, Michael E Prime, Matt R Lee, Vinod Khetarpal, Christopher J Brown, Christoph Scheich

J Med Chem· August 2020

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Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Michael F Mesleh, Jason B Cross, Jing Zhang, Jan Kahmann, Ole A Andersen, Christoph Scheich

Bioorg Med Chem Lett· February 2016

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Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen.
Christoph Scheich, Zoltán Szabadka, Beáta Vértessy, Vera Pütter, Vince Grolmusz

PLoS One· July 2012

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Structure and function of the human sperm-specific isoform of protein kinase A (PKA) catalytic subunit Cα2.
Tuva H Hereng, Paul H Backe, Jan Kahmann, Christoph Scheich, Magnar Bjørås

J Struct Biol· June 2012

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Novel small molecule inhibitors of MDR Mycobacterium tuberculosis by NMR fragment screening of antigen 85C.
Christoph Scheich, Vera Puetter, Markus Schade

J Med Chem· December 2010

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High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand.
Robert Cheng, Brunella Felicetti, Shilpa Palan, Ian Toogood-Johnson, Christoph Scheich

Protein Sci· January 2010

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Novel MK2 inhibitors by fragment screening.
Oliver Keminer, Joachim Kraemer, Jan Kahmann, Ina Sternberger, Christoph Scheich

Comb Chem High Throughput Screen· August 2009

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Structural and functional characterization of human Iba proteins.
Jörg O Schulze, Claudia Quedenau, Yvette Roske, Thomas Adam, Herwig Schüler, Christoph Scheich

FEBS J· September 2008

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Vectors for co-expression of an unrestricted number of proteins.
Christoph Scheich, Daniel Kümmel, Dimitri Soumailakakis, Udo Heinemann, Konrad Büssow

Nucleic Acids Res· May 2007

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Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold.
Babu A Manjasetty, Konrad Büssow, Martin Fieber-Erdmann, Yvette Roske, Johan Gobom, Christoph Scheich

Protein Sci· April 2006

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X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Babu A Manjasetty, Frank H Niesen, Christoph Scheich, Yvette Roske, Frank Goetz

BMC Struct Biol· December 2005

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Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones.
Konrad Büssow, Christoph Scheich, Volker Sievert, Ulrich Harttig, Jörg Schultz

Microb Cell Fact· July 2005

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A catalog of human cDNA expression clones and its application to structural genomics.
Konrad Büssow, Claudia Quedenau, Volker Sievert, Janett Tischer, Christoph Scheich

Genome Biol· May 2005

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Crystal structure of Homo sapiens protein hp14.5.
Babu A Manjasetty, Heinrich Delbrück, Dinh-Trung Pham, Uwe Mueller, Martin Fieber-Erdmann, Christoph Scheich

Proteins· March 2004

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Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis.
Christoph Scheich, Dietmar Leitner, Volker Sievert, Martina Leidert, Brigitte Schlegel

BMC Struct Biol· March 2004

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An automated in vitro protein folding screen applied to a human dynactin subunit.
Christoph Scheich, Frank H Niesen, Robert Seckler, Konrad Büssow

Protein Sci· February 2004

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An automated method for high-throughput protein purification applied to a comparison of His-tag and GST-tag affinity chromatography.
Christoph Scheich, Volker Sievert, Konrad Büssow

BMC Biotechnol· July 2003

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