Publications by authors named "Markus Schade"

Claim this Profile
L
Lessons learned in linking PROTACs from discovery to the clinic.
Andy Pike, Esther C Y Lee, Iacovos N Michaelides, Markus Schade, Ankit Sharma

Nat Rev Chem· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool.
J Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, Ulf Börjesson, Mark J Bostock, Markus Schade

J Med Chem· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Property-based optimisation of PROTACs.
James S Scott, Iacovos N Michaelides, Markus Schade

RSC Med Chem· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural and Physicochemical Features of Oral PROTACs.
Markus Schade, James S Scott, Thomas G Hayhow, Andy Pike, Ina Terstiege

J Med Chem· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Negative cooperativity in the formation of H-bond networks involving primary anilines.
Fergal E Hanna, Alexander J Root, Markus Schade, Christopher A Hunter

Chem Sci· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC.
Thomas G Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L Braybrooke, Markus Schade

Commun Biol· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1.
David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, Kevin Embrey, Philip B Rawlins, Markus Schade

Proc Natl Acad Sci U S A· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In-Cell Quantification of Drugs by Magic-Angle Spinning Dynamic Nuclear Polarization NMR.
Andrea Bertarello, Pierrick Berruyer, Markus Artelsmair, Charles S Elmore, Sepideh Heydarkhan-Hagvall, Markus Schade

J Am Chem Soc· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Q
Quantification of magic angle spinning dynamic nuclear polarization NMR spectra.
Andrea Bertarello, Pierrick Berruyer, Urban Skantze, Samiksha Sardana, Malvika Sardana, Markus Schade

J Magn Reson· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors.
Markus Schade, Beatrix Merla, Bernhard Lesch, Markus Wagener, Simone Timmermanns

J Med Chem· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors.
Jo Alen, Markus Schade, Markus Wagener, Frank Christian, Sonja Nordhoff

J Med Chem· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.
Carolyn Vargas, Gerald Radziwill, Gerd Krause, Anne Diehl, Sandro Keller, Markus Schade

ChemMedChem· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen.
Christoph Scheich, Zoltán Szabadka, Beáta Vértessy, Vera Pütter, Vince Grolmusz, Markus Schade

PLoS One· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis.
Thulasi Warrier, Marielle Tropis, Jim Werngren, Anne Diehl, Martin Gengenbacher, Markus Schade

Antimicrob Agents Chemother· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and structure of stapled peptides binding to estrogen receptors.
Chris Phillips, Lee R Roberts, Markus Schade, Richard Bazin, Andrew Bent

J Am Chem Soc· June 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel small molecule inhibitors of MDR Mycobacterium tuberculosis by NMR fragment screening of antigen 85C.
Christoph Scheich, Vera Puetter, Markus Schade

J Med Chem· December 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Mangesh Joshi, Carolyn Vargas, Prisca Boisguerin, Annette Diehl, Gerd Krause, Markus Schade

Angew Chem Int Ed Engl· June 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NMR fragment screening: Advantages and applications.
Markus Schade

IDrugs· February 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NMR fragment screening: tackling protein-protein interaction targets.
Markus Schade, Hartmut Oschkinat

Curr Opin Drug Discov Devel· May 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro.
Jan D Kahmann, Diana A Wecking, Vera Putter, Ky Lowenhaupt, Yang-Gyun Kim, Markus Schade

Proc Natl Acad Sci U S A· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis