Publications by authors named "Christophe Boldron"

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Every Compound a Candidate: experience-led risk-taking approaches to accelerate small-molecule drug discovery.
Dermot F McGinnity, Jerome Meneyrol, Christophe Boldron, Craig Johnstone

Drug Discov Today· May 2025

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Real-World Applications and Experiences of AI/ML Deployment for Drug Discovery.
Will R Pitt, Jonathan Bentley, Christophe Boldron, Lionel Colliandre, Carmen Esposito

J Med Chem· January 2025

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A Stereocontrolled Total Synthesis of Lipoxin B4 and its Biological Activity as a Pro-Resolving Lipid Mediator of Neuroinflammation.
C Frank Lee, Carla E Brown, Alexander J Nielsen, Changmo Kim, Izhar Livne-Bar, Christophe Boldron

Chemistry· June 2022

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N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Christophe Boldron, Angélina Besse, Marie-Françoise Bordes, Stéphanie Tissandié, Xavier Yvon

J Med Chem· September 2014

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Preparation and study of new poly-8-hydroxyquinoline chelators for an anti-Alzheimer strategy.
Céline Deraeve, Christophe Boldron, Alexandrine Maraval, Honoré Mazarguil, Heinz Gornitzka

Chemistry· March 2008

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New approach for the preparation of efficient DNA cleaving agents: ditopic copper-platinum complexes based on 3-Clip-Phen and cisplatin.
Paul de Hoog, Christophe Boldron, Patrick Gamez, Karen Sliedregt-Bol, Isabelle Roland

J Med Chem· June 2007

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Selective oxidative para C-C dimerization of 2,6-dimethylphenol.
Christophe Boldron, Guillem Aromí, Ger Challa, Patrick Gamez, Jan Reedijk

Chem Commun (Camb)· December 2005

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Preparation of cyclo-phen-type ligands: chelators of metal ions as potential therapeutic agents in the treatment of neurodegenerative diseases.
Christophe Boldron, Ingrid Van der Auwera, Céline Deraeve, Heinz Gornitzka, Stefaan Wera

Chembiochem· November 2005

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Selective copper(II)-mediated oxidative coupling of a nucleophilic reagent to the para-methyl group of 2,4,6-trimethylphenol.
Christophe Boldron, Seniz Ozalp-Yaman, Patrick Gamez, Duncan M Tooke, Anthony L Spek

Dalton Trans· November 2005

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Copper-mediated selective oxidation of a C-H bond.
Christophe Boldron, Patrick Gamez, Duncan M Tooke, Anthony L Spek, Jan Reedijk

Angew Chem Int Ed Engl· June 2005

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Cytostatic activity of 1,10-phenanthroline derivatives generated by the clip-phen strategy.
Marguerite Pitié, Alain Croisy, Danièle Carrez, Christophe Boldron, Bernard Meunier

Chembiochem· April 2005

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Complexes of a novel multinucleating poly-beta-diketonate ligand.
Guillem Aromi, Christophe Boldron, Patrick Gamez, Olivier Roubeau, Huub Kooijman

Dalton Trans· November 2004

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Acridine conjugates of 3-clip-phen: influence of the linker on the synthesis and the DNA cleavage activity of their copper complexes.
Christophe Boldron, Steven A Ross, Marguerite Pitié, Bernard Meunier

Bioconjug Chem· June 2003

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